Clinical trials: Preoxygenation
Anesthesia, ASA Physical Status I
Descriptive Observational Study of Patient-performed Pre-oxygenation
The aim of this research would be to determine the efficacy and effects of preoxygenation when performed by the patient (mask held by the patient). This is the concept of "self-preoxygenation".
- Conditions
- Anesthesia, ASA Physical Status I, ASA Physical Status II
- Trial name
- ApréOx (NCT06361693)
- Testing
- Auto-preoxygenation, APAIS scale, Visual analog anxiety scale (VAS-A)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Hypoxemic Respiratory Failure
Benefits of Optiflow® Device for Preoxygenation Before Intubation in Acute Hypoxemic Respiratory Failure : The PREOXYFLOW Study
Oro-tracheal intubation in intensive unit care(ICU) in acute hypoxemic respiratory failure after crash induction remains a critical event.
- Trial name
- PREOXYFLOW (NCT01747109)
- Testing
- PREOXYFLOW, STANDARD FACE MASK
- Where
- 6 sites in France
- Volunteers
- 122 people
- Sponsor
- Nantes University Hospital
Hypoxia
Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation
This is a prospective randomized cross over study of healthy volunteers comparing end-tidal oxygen concentration among subjects undergoing continuous positive airway pressure ventilation via a noninvasive ventilation (NIV) mask…
- Trial name
- NCT03093662
- Testing
- Ventilation with nasal cannula, Ventilation without nasal cannula
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Respiratory Failure
Bag Valve Mask vs Non-rebreather at Flush Rate
Healthy volunteers will participate in a crossover trial comparing preoxygenation with a non-rebreather mask to a bag-valve mask (with and without a simulated mask leak) at the flush rate of oxygen (fully opening standard oxygen…
- Trial name
- NCT02798302
- Testing
- Flush rate oxygen using a standard flowmeter (Precision Medical, 8MFA). See description for details. This is specific.
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Time to Reach 90% Endtidal Oxygen During Preoxygenation
The Comparison of the Methods Applied in Bariatric Surgery in Terms of Preoxygenation Time
The aim of the study was to evaluate the preoxygenation time by observing patients undergoing preoxygenation with CPAP (Continuous Positive Airway Pressure) and Mask Ventilation in the clinic.
- Trial name
- NCT03807375
- Testing
- CPAP preoxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Diskapi Training and Research Hospital
Intubation Complication
End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients
Recent studies have shown that end tidal oxygen (ETO2) monitoring can be useful to determine the adequacy of preoxygenation. No study has assessed the correlation between ETO2 values obtained during preoxygenation to predict the…
- Trial name
- NCT03842306
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- New York City Health and Hospitals Corporation
Preoxygenation, Intubation
Impact of Preoxygenation Time on End-tidal Oxygen Concentration and on Hypoxic Events Occurring After Intubation in the Intensive Care Unit.
Preoxygenation is recommended before performing tracheal intubation. In intensive care units (ICU) patients, there is no specific recommendation regarding the duration of preoxygenation, which usually is applied for 3 to 5…
- Conditions
- Preoxygenation, Intubation, Intensive Care Unit
- Trial name
- IMPROVE (NCT04148443)
- Testing
- Preoxygenation, Preoxygenation (longer)
- Where
- 3 sites in France
- Sponsor
- Centre Hospitalier Régional d'Orléans
General Anesthesia
Safe Use of CPAP and PEEP During Induction of General Anesthesia
The study compares the safety of using pressure controlled ventilation with a positive end-expiratory pressure (PEEP) during induction of general anaesthesia immediately after apnoea to a standard method starting ventilation…
- Trial name
- NCT04271683
- Testing
- Pressure controlled ventilation with PEEP, Manual ventilation without PEEP
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Region Västmanland
Hypoxemia During Surgery
Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy
To investigate the independent effects and interaction of pre-oxygenation position (left lateral vs left lateral with 30° head-up tilt) and examination position (left lateral vs left lateral with 30° head-up tilt) on hypoxemia…
- Trial name
- NCT07673042
- Testing
- Pre-oxygenation Position （left lateral position）, Examination Position（left lateral position ）, Pre-oxygenation Position（ left lateral head elevation in a 30-degree position）
- Where
- China
- Volunteers
- 208 people
- Sponsor
- General Hospital of Ningxia Medical University
Preoxygenation
Preoxygenation Before Prehospital Tracheal Intubation With NIV Versus Balloon
Recent studies reports feasibility, effectiveness and even less complications of using NIV for preoxygenation during tracheal intubation in ICU and in Operating Room.
- Trial name
- PREOXY (NCT01232153)
- Testing
- Non invasive ventilation
- Where
- France
- Sponsor
- Hopital of Melun
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anesthesia, Preoxygenation
Preoxygenation Before General Anesthesia
Rationale of the study: we aim to clarify the question (related to still unclear and not univocal response) about the protective or unnecessary role of preoxygenation in non-critically ill patients (otherwise with no high risk of…
- Trial name
- PREOX2018 (NCT03802643)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Parma
Pre-operative Exercise
Evaluation of the Effects of Preoperative Breathing Exercises on Preoxygenation Period
The aim of this observational study is to compare the effects of preoperative breathing exercises during the preoxygenation period in patients undergoing abdominal surgery.
- Trial name
- NCT06401096
- Testing
- Preoperative respiratory exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Hypoxemia
Pre-oxygenation in Sitting Position and Oxygen Reserve Index
This prospective, controlled and randomized study aims at comparing the effect of position on the oxygen reserve index alarm time which is considered as predictor of hypoxemia in prolonged apnea which might be faced during…
- Trial name
- NCT05964309
- Testing
- supine group, sitting group
- Where
- Saudi Arabia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Preoxygenation, Anaesthesia
Quality of Preoxygenation in Emergency Surgery
Preoxygenation prior to general anaesthesia prolongs safe apnea time. Proper preoxygenation is always a challenge in emergency surgery.
- Conditions
- Preoxygenation, Anaesthesia, Emergencies, Surgery
- Trial name
- NCT04070404
- Where
- Lithuania
- Volunteers
- 200 people
- Sponsor
- Vilnius University
Intraoperative Complications, Respiratory Complication
Lower Inspiratory Oxygen Fraction for Preoxygenation
During the induction period of general anesthesia, surgical patients are inevitably experienced a short period of apnea for endotracheal intubation or other airway manipulation.
- Conditions
- Intraoperative Complications, Respiratory Complication, Oxygen Toxicity, Oxygen Deficiency
- Trial name
- NCT03665259
- Testing
- Pure oxygen group, Lower oxygen group
- Where
- Taiwan
- Volunteers
- 304 people
- Sponsor
- E-DA Hospital
Sarcopenia, Handgrip Strength Test
Preoperative Performance Indicators, Preoxygenation and Oxygen Reserve Relationship
The goal of this observational study is to evaluate the relationship between preoperative cardiopulmonary performance indicators and preoxygenation efficiency along with oxygen reserve depletion in patients scheduled for elective…
- Conditions
- Sarcopenia, Handgrip Strength Test, Preoxygenation
- Trial name
- NCT07688941
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Preoxygenation
Verbal Breathing Coaching to Improve Preoxygenation and Extend Safe Apnea Time in Anesthesia
This study explores whether simply guiding patients to breathe slowly and calmly before anesthesia can help improve oxygen levels and keep them safe for longer during induction.
- Trial name
- NCT07565259
- Testing
- Verbal Breathing Coaching
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prince Sultan Military Medical City
Obesity, Anesthesia
Pre-oxygenation Methods in Bariatric Patients
The purpose of the study is to compare effectiveness of different methods of achieving pre-oxygenation in bariatric patients. The investigators intend to compare facemask pre-oxygenation with a high-flow humidified nasal oxygen.
- Conditions
- Obesity, Anesthesia, Bariatric Surgery Candidate
- Trial name
- NCT03428256
- Testing
- Optiflow and THRIVE technique, Standard anaesthetic face mask
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Acute Hypoxemic Respiratory Failure
Impact of End-tidal Oxygen Monitoring During Preoxygenation Before Intubation for Acute Hypoxemic Respiratory Failure in ICU Setting
The main objective of this pilot study is to determine if our protocole using EtO2 monitoring during preoxygenation before intubation is feasible in a population of critically ill patients in acute hypoxemic respirator failure…
- Trial name
- PFOX (NCT06198504)
- Testing
- Protocol using end-tidal oxygen monitoring during preoxygenation before intubation
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Grenoble