Clinical trials: Preoperative Patients
Esophageal Cancer, Gastric Cancer
Radiation Therapy and Paclitaxel, Carboplatin, and Fluorouracil Followed by Esophagectomy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy, such as paclitaxel, carboplatin, and fluorouracil, work in different ways to stop tumor cells from dividing so they stop…
- Trial name
- NCT00022139
- Testing
- carboplatin, fluorouracil, paclitaxel
- Where
- 35 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Rectal Cancer
Preoperative Combined Radiochemotherapy for Patients With Rectal Carcinoma
Rate of T-downstaging (Reduction of the T-stadium) at the time of final surgery following the preoperative combined radiochemotherapy (chemotherapy: Oxaliplatin, Capecitabine) Evaluation of the toxicity grade III and IV of the…
- Trial name
- NCT00297141
- Testing
- Capecitabine, Oxaliplatin
- Where
- 8 sites in Austria
- Volunteers
- 60 people
- Sponsor
- Austrian Breast & Colorectal Cancer Study Group
Pancreaticoduodenectomy, Antibiotherapy
Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent
The main objective of the study is to compare 2 broad-spectrum antibiotic (Piperacillin / Tazobactam) treatment modalities, following pancreaticoduodenectomy in patients with preoperative biliary stent, to demonstrate the…
- Trial name
- FRENCH24 ANIS (NCT06123169)
- Testing
- Antibioprophylaxis (Piperacillin-tazobactam), 5 days Antibiotherapy (Piperacillin-tazobactam)
- Where
- France
- Volunteers
- 326 people
- Sponsor
- University Hospital, Rouen
Abdominal Aortic Aneurysm
Prognostic Impact of NLR, PLR, and MPV in Patients Undergoing AAA Open Repair
Abdominal aortic aneurysm (AAA) is a multifactorial degenerative disorder, which if untreated might lead to catastrophic complications.
- Trial name
- NCT05031195
- Testing
- 1st tertile, 2nd tertile, 3rd tertile
- Where
- South Korea
- Volunteers
- 334 people
- Sponsor
- Gangnam Severance Hospital
Skin Cancer, Skin Wound
Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery
This research study aims to understand whether visual and written education on wound appearance can improve patients' experience and understanding of what their wound will look like following dermatologic surgery.
- Trial name
- NCT05643755
- Testing
- Preoperative image-based education
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Lung Neoplasms, Thoracoscopic Lung Resection
Patient-Specific 3D Model-Assisted Preoperative Consultation for Thoracoscopic Lung Resection
This study is a single-center, cluster randomized controlled trial evaluating whether lung three-dimensional model-assisted preoperative consultation can improve shared decision-making in adult patients undergoing thoracoscopic…
- Conditions
- Lung Neoplasms, Thoracoscopic Lung Resection, Shared Decision Making, Preoperative Counseling
- Trial name
- NCT07686549
- Testing
- Lung three-dimensional model and reconstruction-assisted preoperative consultation, Usual preoperative consultation
- Volunteers
- 132 people
- Sponsor
- Tongji Hospital
Locally Advanced Rectal Cancer
Development of a Genome-based Platform for Personalized Treatment in Locally Advanced Rectal Cancer Patients
This study is aimed to develop a genome-based platform to predict patients who can achieve pathologic complete response after neoadjuvant treatment in locally advanced rectal cancer.
- Trial name
- NCT04738214
- Testing
- Neoadjuvant CCRT+operation +/- adjuvant treatment
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Yonsei University
Cancer, Surgery
Protein Supplements in Association With Prehabilitation Program for Cancer Patients Before Surgery
The aim of study is to analyse the feasibility of the use of nutritionnal complements after exercices before surgery for cancer. Body composition, muscle function and muscle mass will be analyse too.
- Conditions
- Cancer, Surgery, Prehabilitation
- Trial name
- NCT04812704
- Testing
- Whey protein
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Difficult Airway, Difficult Laryngoscopy
Comparative Analysis of a Preoperative Airway Ultrasound Protocol and Direct Laryngoscopy in Oncologic Surgery Patients
This prospective observational study evaluated the predictive performance of the Difficult Airway Evaluation with Sonography (DARES) protocol for identifying difficult laryngoscopy and other airway management difficulties in…
- Conditions
- Difficult Airway, Difficult Laryngoscopy, Oncologic Surgery, Airway Management
- Trial name
- NCT07813104
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Heart Diseases, Atrial Fibrillation
Clinical Value of Remote Ischemic Preconditioning
Objectives: Despite utilization of available means for cardioprotection during cardiac surgery, myocardial injury still occurs. Further improvement of cardioprotection is therefore necessary.
- Trial name
- NCT01740102
- Testing
- RIPC
- Where
- Norway
- Volunteers
- 92 people
- Sponsor
- Norwegian University of Science and Technology
Gingival Recession, Dental Anxiety
Impact of Preoperative Anxiety on Postoperative Quality of Life After Free Gingival Graft Surgery
This study investigates the effect of free gingival graft (FGG) surgery on patients' oral health-related quality of life (QoL) during the first postoperative month and evaluates the role of preoperative anxiety on postoperative…
- Conditions
- Gingival Recession, Dental Anxiety, Quality of Life
- Trial name
- FGG-QoL (NCT07258472)
- Testing
- Free Gingival Graft (FGG) Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Hysterectomy, Informed Consent
Informed Consent for Hysterectomy: Effectiveness of Audio-visual Presentations on Patient Comprehension
To determine whether the addition of audio-visual presentations to standard physician interaction improves patient comprehension as it relates to the information provided during the informed consent process in patients undergoing…
- Trial name
- NCT01933139
- Testing
- Audio-visual presentation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Delirium in Old Age, Neurocognitive Disorders
Preoperative Cognitive Impairment Predicts Postoperative Delirium
Preoperative cognitive impairment (PCI) may increase the incidence of postoperative delirium (POD), yet screening for cognitive impairment is rarely performed.
- Conditions
- Delirium in Old Age, Neurocognitive Disorders, Cognitive Impairment
- Trial name
- NCT05798767
- Testing
- Neuropsychological tests
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Henan Provincial People's Hospital
Cardiac Arrhythmias, Hemorrhage
Tapered Warfarin or Interrupted Warfarin With Heparin Bridging for Pacemaker or Defibrillator Implantation
Approximately 2 million patients in North America are currently treated with the blood thinner warfarin. These patients have every year more than 200,000 invasive procedures, for which warfarin must be stopped to avoid bleeding…
- Conditions
- Cardiac Arrhythmias, Hemorrhage, Thromboembolism
- Trial name
- PACEBRIDGE (NCT02094157)
- Testing
- Tapered warfarin regimen, Bridged regimen Low-molecular-weight heparin
- Where
- 2 sites in Canada
- Volunteers
- 173 people
- Sponsor
- McMaster University
Gastric Cancer, Gastroesophageal-junction Cancer
Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma
The purpose of this study is to evaluate the efficacy of Tislelizumab in the neoadjuvant (prior to surgery) or adjuvant (after surgery) treatment of previously untreated adults with gastric and gastroesophageal junction (GEJ)…
- Trial name
- NCT05687357
- Testing
- Tislelizumab, S-1, Oxaliplatin
- Where
- 3 sites in China
- Volunteers
- 140 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Pancreatic Carcinoma
Preoperative Biliary Drainage in Resectable Pancreatic or Periampullary Cancer
The purpose of this study is to demonstrate that preoperative biliary drainage using self-expanding metal stents (SEMS) does not negatively impact overall surgical outcomes in patients undergoing pancreaticoduodenectomy for…
- Trial name
- NCT01774019
- Testing
- WallFlex™ Biliary RX Fully Covered/Uncovered Stent System
- Where
- 11 sites in United States, Australia and 7 more
- Volunteers
- 284 people
- Sponsor
- Boston Scientific Corporation
Dental Anxiety
Comparing Binaural Beats and 432Hz Music for Reduction of Preoperative Anxiety in Root Canal Patients
Many patients suffer from dental anxiety and don't go to dentists for regular checkups. This can lead to the initiation and progression of dental caries, which, if not controlled at the right time, can lead to the loss of the…
- Trial name
- NCT06349200
- Testing
- 432 Hz music, Binaural beats, White noise
- Where
- Pakistan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Gastric Cancer
Prognostic Values of Inflammation-based Indices in Gastric Cancer
This study aims to evaluate the prognostic values of preoperative inflammation-based indices in patients undergoing potentially curative resection of gastric cancer.
- Trial name
- NCT05075421
- Testing
- Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Gulhane Training and Research Hospital
Breast Cancer
Preoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breast Cancer
This study evaluates the acute toxicity and feasibility of repeat breast conserving therapy with preoperative accelerated partial breast re-irradiation (PAPBI) in female patients aged 51 years or older with ipsilateral recurrent…
- Trial name
- PAPBI-3 (NCT06362616)
- Testing
- Preoperative accelerated partial breast irradiation, Breast conserving surgery, Sentinel node procedure
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- The Netherlands Cancer Institute
Colorectal Cancer
An Observational Study of Xeloda (Capecitabine) and Oxaliplatin Prior and Concurrent To Preoperative Pelvic Radiotherapy in Patients With Locally Advanced Rectal Cancer
This observational study is a follow-up study of protocol ML18280. Survival data of patients who took part in and concluded study ML18280 will be collected for up to 5 years after LPLV of ML18270.
- Trial name
- NCT01339832
- Where
- 5 sites in Switzerland
- Volunteers
- 51 people
- Sponsor
- Hoffmann-La Roche