Clinical trials: Preoperative Patients
Anxiety, Anesthesia, General
Nurse Anesthesist Assessment of Patient Preoperative Anxiety
Preoperative anxiety is a major concern for patients who undergo surgery. To accurately identify anxious patient is therefore crucial to improve perioperative patient care.
- Trial name
- EVALANXI (NCT04752423)
- Testing
- Pre operative assessment
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
SARS CoV 2 Infection, Cancer
Mortality of Cancer Surgery During SARS CoV2 Pandemic
The impact of cancer surgery during covid epidemic is not clear. The published reports show contradictory findings that extend from no change in mortality to increased mortality, further no data on exposure and outcome of health…
- Trial name
- NCT05240378
- Testing
- Surgery
- Where
- India
- Volunteers
- 1,576 people
- Sponsor
- Banaras Hindu University
Total Knee Arthroplasty
Personalized Information Before and After Total Knee Arthroplasty: PAK-study
Despite positive results following total knee arthroplasty (TKA), some patients are dissatisfied after recovery. Unfulfilled expectations is a key predictor of dissatisfaction.
- Trial name
- PAK (NCT05266482)
- Testing
- Personal report
- Where
- Netherlands
- Volunteers
- 461 people
- Sponsor
- Kliniek ViaSana
Preoperative, Sleep Disturbance
Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
Previous studies have indicated a high incidence of sleep disturbances and anxiety symptoms in individuals with colorectal cancers prior to undergoing surgery, leading to worsened postoperative pain, slower recovery, and higher…
- Conditions
- Preoperative, Sleep Disturbance, Anxiety, Midazolam
- Trial name
- POMPPR (NCT06407518)
- Testing
- Midazolam oral solution
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Ventricular Dysfunction, Left, Hip Fracture
Preoperative levosimendán and Hip Fracture
The purpose of this study is to evaluate whether preoperative optimization with levosimendan in heart failure patients undergoing hip fracture surgery improves haemodynamic and tissue perfusion parameters.
- Trial name
- OPL (NCT02972918)
- Testing
- Levosimendan
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Hospital Universitario de Canarias
Gastric Cancer
Combination Chemotherapy and Surgery in Treating Patients With Locally Advanced Stomach Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery may kill more tumor cells.
- Trial name
- NCT00005060
- Testing
- Taxotere-Cisplatin-5FU, Immediate surgery
- Where
- 3 sites in Italy, Switzerland
- Volunteers
- 240 people
- Sponsor
- Swiss Cancer Institute
Breast Cancer
Efficacy of Preoperative Pectoral Nerve Block for Intraoperative Opioid Sparing Effect and Postoperative Analgesia
The purpose of this study is to determine whether pectoral nerves blocks（PECS） would reduces the opioid consumption during the surgery and postoperative pain after breast cancer surgery.
- Trial name
- NCT03210220
- Testing
- Pecs II block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Gachon University Gil Medical Center
Breast Cancer
A Pilot Study of a Brief Pre-Operative Intervention for Patients Undergoing Breast Surgery
This study is to assess the feasibility of using a positive activities intervention, Positive Piggy Bank, in newly diagnosed women with breast cancer who will soon undergo surgery.
- Trial name
- NCT02939040
- Testing
- Positive Activities
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Aspiration Pneumonia, Gastric Volume
Gastric Ultrasound for Preoperative Assessment of Gastric Content in Diabetic Patients
ASA fasting guidelines are only applicable to healthy elective surgery patients. Measuring gastric volume now is not easy, and scintigraphy has remained the gold standard technique for many years.
- Trial name
- NCT04181814
- Testing
- Ultrasound
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy
Association of Preoperative Sarcopenia and Intraoperative Hypotension in Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy : Prospective Observational Study
The aim of this study is to determine whether preoperative sarcopenia (low muscle strength/muscle mass) is correlated with time weighted average intraoperative hypotension in patients undergoing minimally invasive pylorus…
- Trial name
- NCT05320978
- Testing
- Hand grip test, computed tomography
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yonsei University
Endometrial Cancer, Serous Adenocarcinoma
Niraparib in High-grade Endometrial Cancer Trial
The study will investigate the effect of niraparib on tumor tissue in chemotherapy naïve, newly diagnosed, high-grade endometrial cancer patients.
- Conditions
- Endometrial Cancer, Serous Adenocarcinoma, Uterine Neoplasm
- Trial name
- NIREC (NCT05289648)
- Testing
- Niraparib oral capsule
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Lung Diseases, Obstructive, Postoperative Complications
Preoperative Diagnostic Tests for Pulmonary Risk Assessment in COPD
This prospective study intends to investigate the incidence of postoperative pulmonary complications (PPC) or in-hospital mortality in patients with COPD or at risk for COPD undergoing high-risk noncardiac major surgery and to…
- Trial name
- PredicT (NCT02566343)
- Where
- Germany
- Volunteers
- 365 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Pain, Fracture Femur
Preoperative and Postoperative Comparison of Two Nerve Blocks in Intertrochanteric Fracture Surgery
Patients with intertrochanteric femur fractures experience significant perioperative and postoperative pain. Perioperative pain can complicate and prolong the anesthesia process for patients undergoing spinal anesthesia, leading…
- Trial name
- NCT07075432
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Erzincan University
Emergence Time
Effects of Preoperative Sleep Disorders on Perioperative Anesthesia Depth and Recovery Quality in Patients Undergoing Noncardiac Surgery
A Single-Center, Prospective Observational Cohort Study Comparing Perioperative Electroencephalographic Anesthesia Depth Parameters (Electroencephalographic Index, SE/RE Entropy, Burst Suppression Ratio) Between Patients With…
- Trial name
- NCT07675993
- Testing
- Exposed cohort (sleep disorder group), Control cohort (non-sleep disorder group)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Colostomy, Hirschsprung Disease - Pull Through
Bowel Preparation in Elective Pediatric Colorectal Surgery
Infections after elective intestinal surgery remain a significant burden for patients and for the health care system. The cost of treating a single surgical site infection is estimated at approximately $27,000.
- Conditions
- Colostomy, Hirschsprung Disease - Pull Through, Necrotizing Enterocolitis, Inflammatory Bowel Diseases
- Trial name
- NCT03593252
- Testing
- Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral
- Volunteers
- 81 people
- Sponsor
- McMaster University
Bariatric Surgery Candidate, Ketogenic Dieting
Ketogenic Diet Prior to Bariatric Surgery
Standard dietary regiments for bariatric are advised prior to surgery. The most used diet is a very low calorie diet (VLCD). These diets potentially have multiple pittfalls.
- Trial name
- NCT06850493
- Testing
- VLCKD (ketogenic diet), VLCD (Very-low-calorie-diet)
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Bariatric Surgery Candidate, Obesity
The Effect of Exercise in Patients Awaiting Bariatric Surgery
The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery.
- Trial name
- BariPrehab (NCT05235945)
- Testing
- Online exercise intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Pelvic Organ Prolapse
Centered Surgery - Preoperative Counseling and Patient Satisfaction
This study is a prospective cohort study which aims to assess patient satisfaction and preparedness for surgery through two methods of preoperative counseling: standard individual phone calls versus virtual group sessions called…
- Trial name
- NCT07471464
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- The Cleveland Clinic
Esophageal Carcinoma
Chemoradiation and Tetrathiomolybdate (TM) in Patients With Esophageal Carcinoma
Surgery has been the standard of care for esophageal cancer for many years, with limited success. At present, several studies are underway nationwide which utilize chemotherapy combined with radiation therapy prior to the usual…
- Trial name
- NCT00176800
- Testing
- Tetrathiomolybdate (TM), Radiation, Surgery
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Michigan Rogel Cancer Center
Glioblastoma Multiforme, Meningioma
Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients
In the proposed trial, patients will be administered ribociclib prior to surgical resection of their tumor. Patients will be enrolled in time-intervals sequentially (non-randomized).
- Trial name
- NCT02933736
- Testing
- Ribociclib
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nader Sanai