Clinical trials: Premenopause
Menopause, Perimenopause
Effects of Hemp-Derived Cannabinoids on Menopause Symptoms
The purpose of the study is to examine the impact of hemp-derived minor cannabinoids on symptoms of menopause/perimenopause.
- Trial name
- NCT07393672
- Testing
- Hemp-derived cannabinoids
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Washington State University
Perimenopause, Menopause
Our Transitions: Improving the Path to Menopause With Personal Digital Health Technologies
The goal of this observational study is to build knowledge about the path to menopause using subjective, self-reported and objectively measured information from multiple wearable study devices and a smartphone app.
- Trial name
- NCT07597915
- Volunteers
- 1,250 people
- Sponsor
- 4YouandMe
Physical Exercise
The Effect of Exercise on Ovarian Reserve
The purpose of this study is to examine how different levels of physical activity impact the ovarian reserve during the pre-menopausal period
- Trial name
- NCT02999568
- Testing
- Physical exercise
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Menopausal Complaints, Vaginal Atrophy
Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV
This is a research study about the effects of vaginal estradiol compared to moisturizer on vaginal symptoms of menopause and the microbiome in women with HIV.
- Conditions
- Menopausal Complaints, Vaginal Atrophy, Genitourinary Symptoms, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07526948
- Testing
- Vaginal estradiol tablets, Vaginal moisturizer
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Muscle Mass and Strength, Obesity & Overweight
Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment
This study aims to investigate the effect that a structured, progressive resistance exercise program may have on maintaining the muscle mass and physical function of overweight/ obese females whilst they experience a tirzepatide…
- Conditions
- Muscle Mass and Strength, Obesity & Overweight, Physical Function
- Trial name
- FLEX (NCT07457437)
- Testing
- Progressive Resistance Exercise Training Program, Habitual physical activity guidelines
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Perimenopause, Postmenopause
Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause
This study will evaluate the effects of a plant extract-based dietary supplement on menopausal symptoms and health indicators in women with late perimenopause or early postmenopause.
- Conditions
- Perimenopause, Postmenopause, Hot Flashes
- Trial name
- NCT07863973
- Testing
- Plant Extract-Based Dietary Supplement
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Hormone, Cardiovascular
Cardiometabolic and Hormonal Adaptations to 4-Month Zumba Training in Overweight/Obese Women
This study aims to evaluate the effects of a 4 month Zumba training program on cardiometabolic, hormonal, inflammatory, hepatic, renal, and functional parameters in overweight and obese women.
- Conditions
- Hormone, Cardiovascular, Obesity & Overweight
- Trial name
- NCT07264348
- Testing
- Zumba training
- Volunteers
- 73 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Healthy Women
GLOW Study: Effects of Triple Protein in Women
This single-site, randomized, blinded, placebo-controlled study will evaluate whether 4 weeks of daily Triple Support Protein powder improves glycemic control and overall well-being in healthy women aged 30-60 years.
- Trial name
- NCT07526571
- Testing
- Triple protein support
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Perimenopause-Related Depression
Estrogen Receptor Beta and Mood
Background: Our previous studies have found that women who had depression during the perimenopause may have mood symptoms again if they stop estrogen therapy.
- Trial name
- NCT03689543
- Testing
- Estradiol, ER Beta Agonist, Provera
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- National Institute of Mental Health (NIMH)
Quality of Life, Depression
Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women
This study aims to evaluate the effect of Jin Shin Jyutsu-based hand application guided by the Transactional Model of Stress and Coping on quality of life and psychosocial status in perimenopausal women.
- Conditions
- Quality of Life, Depression, Anxiety, Stress
- Trial name
- NCT07376395
- Testing
- General Health Education, Jin Shin Jyutsu®-Based Hand Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Insomnia, Menopause
No More Sleepless Nights in Perimenopause
The goal of the clinical trial is to learn if Hormone Replacement Therapy (HRT) and Cognitive Behavioral Therapy (CBT-I) can treat insomnia in menopausal women.
- Trial name
- NCT06497894
- Testing
- Cognitive Behavioural Therapy for Insomnia (CBT-I), Hormone Replacement Therapy (HRT), Sleep Hygiene
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Perimenopause, Postmenopause
Effect of Lifestyle Intervention on Menopausal Symptoms, Sleep Quality, and Anxiety in Peri- and Postmenopausal Women
Menopause is a biological process characterized by the permanent cessation of menstruation, often accompanied by vasomotor symptoms, sleep disturbances, anxiety, and impaired quality of life.
- Conditions
- Perimenopause, Postmenopause, Menopause
- Trial name
- NCT07860645
- Testing
- Structured Lifestyle Education, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Premenopause, Healthy
Effect of Race on Gonadotropin Responses
The purpose of this study is to attempt to determine why estrogen levels are increased in African-American women as compared to Caucasian women by evaluating estrogen feedback on the brain.
- Trial name
- NCT00455962
- Testing
- Estradiol steroid infusion, Progesterone steroid infusion
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Perimenopause, Subjective Cognitive Complaints
Exercise in Perimenopause to Improve Cognitive Health
Perimenopause is now considered a possible risk factor for dementia and may contribute to the fact that 2/3 of those living with Alzheimer's disease are females.
- Trial name
- EPIC (NCT07272174)
- Testing
- Progressive Resistance Training, Balance, Flexibility, and Tone Exercises
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Menopausal and Other Perimenopausal Disorders
Mirena and Estrogen for Control of Perimenopause Symptoms and Ovulation Suppression
Hormonal treatment of perimenopausal women has frequently utilized oral contraceptive pills (OCPs). Because of their ability to suppress ovulation and establish cycle control, OCPs have become a popular option, and one that is…
- Trial name
- NCT01613131
- Testing
- Mirena, Estradiol
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Colorado, Denver
Mental Health, Perimenopause
Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women
This study will explore how intermittent fasting (specifically the 16/8 method) affects the mental health of women who are in the perimenopause stage.
- Conditions
- Mental Health, Perimenopause, Intermittent Fasting
- Trial name
- NCT07481513
- Testing
- Intermittent fasting (16/8)
- Where
- Lebanon
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Menopause, Perimenopause
Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women
The purpose of this study is to integrate Traditional Chinese Medicine (TCM) theory and therapeutic methods with modern low-level laser stimulation on corresponding acupoints, applying this combined approach to the field of…
- Conditions
- Menopause, Perimenopause, Obesity, Overweight
- Trial name
- NCT07472881
- Testing
- Multi-acupoint low-level laser therapy, Diet and exercise guidance
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Perimenopause, Depression
Effectiveness and Safety of Electro-acupuncture for Mild-to-moderate Perimenopausal Depression
Main objective: to compare the effects of electro-acupuncture and escitalopram oxalate tablets on mild-to-moderate perimenopausal depression, and to evaluate the safety of electroacupuncture stimulation.
- Trial name
- NCT02423694
- Testing
- electro-acupuncture, escitalopram oxalate tablets
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Menopause Symptoms
The Impact of Concurrent Training on Women Experiencing Symptoms of Menopause
The aim of this study is to examine the impact of a concurrent training exercise intervention on menopausal symptoms and key physical and mental health outcomes.
- Trial name
- NCT07417228
- Testing
- Concurrent training
- Where
- Ireland
- Volunteers
- 90 people
- Sponsor
- University College Dublin
Menopause, Postmenopause
Midlife Cholesterol Study
The postmenopausal state is associated with an increase risk for heart disease. Much of this increase in risk may be due to the loss of estrogen (the main female hormone) and the effect of this loss on lipids (blood fats).
- Conditions
- Menopause, Postmenopause, Premenopause, Cardiovascular Disease
- Trial name
- NCT00361075
- Testing
- transdermal estradiol patch (Vivelle), oral estrogen (Estrace), progesterone (Prometrium)
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Northwestern University