Clinical trials: Prematurity
PreTerm Birth
New Tool to Predict Risk of Spontaneous Preterm Birth in Asymptomatic High-risk Women
The QUIPP tool integrates information of obstetrical history, quantitative fetal fibronectin (qfFN) and cervical length to predict the risk of sPTB in asymptomatic high-risk women.
- Trial name
- NCT03062020
- Testing
- QUIPP
- Where
- 2 sites in Spain
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Neonatal Sepsis
Outcomes and Predictors of Mortality Among Preterm Infants With Neonatal Sepsis
A prospective cross-sectional study of outcomes and predictors of mortality among preterm infants with neonatal sepsis admitted in NICU of Assiut University Children's Hospital
- Trial name
- NCT06113653
- Testing
- Prospective study
- Volunteers
- 50 people
- Sponsor
- Assiut University
Early Interventions, Preterm Infants
Effects of Early Behavioral and Transaction Interventions on Preterm Infants' and Parents' Biopsychosocial Well-being
This randomized controlled trial will use a longitudinal repeated-measures design to examine the effects of two interventions, behavioral support interventions and a parent-infant transactional program, on parents' stress, PPD…
- Conditions
- Early Interventions, Preterm Infants, Parent-Child Relations
- Trial name
- NCT03013023
- Testing
- BS, Routine care, PITP
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Ventricular Tachycardia, Premature Ventricular Contraction
DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation
The purpose of this study is to learn if taking a drug called direct oral anticoagulant after an ablation procedure keeps blood clots from forming and lowers the chance of having a stroke in patients with ventricular tachycardia…
- Conditions
- Ventricular Tachycardia, Premature Ventricular Contraction, Stroke
- Trial name
- STROKE-VT (NCT02666742)
- Testing
- DOAC, Aspirin
- Where
- 5 sites in United States, India
- Volunteers
- 246 people
- Sponsor
- Kansas City Heart Rhythm Institute
Preterm, Premature
Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants
This study aimed to evaluate the effects of kinesio taping on blood gas parameters, respiratory rate, heart rate, oxygen saturation, and pressure limits in preterm infants with RDS who are on NIV.
- Conditions
- Preterm, Premature, Infant, Newborn, Diseases, Respiratory Distress Syndrome
- Trial name
- NCT06285669
- Testing
- kinesiotaping application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ondokuz Mayıs University
Preterm Birth, Asymptomatic Bacteriuria in Pregnancy
Screening and Treating Asymptomatic Bacteriuria Every Trimester and Preterm Birth
This study is evaluating whether screening of a pregnant woman for asymptomatic bacteriuria in each trimester for early detection and treatment of bacteriuria will reduce the incidence of preterm birth in Harare.
- Trial name
- Pretermbirth (NCT03274960)
- Testing
- Griess,
- Where
- Zimbabwe
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Preterm Delivery.
Utility of Tocolytic Therapy for Maintenance Tocolysis in the Management of Threatened Preterm Delivery
Hypothesis: Both nifedipine or progesterone are widely used in clinical practice as maintenance tocolytic therapy after an episode of threatened preterm delivery.
- Trial name
- UTM/2012 (NCT01796522)
- Testing
- progesterone 200 mg / day vaginally, nifedipine (60 mg / day orally)
- Where
- Spain
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Analgesia
Analgesic Efficacy of Oral Glucose in Preterm Neonates During Suctioning
Nasopharyngeal suctioning is a painful procedure that often becomes necessary in the care of preterm infants under CPAP therapy several times a day.
- Trial name
- Glucose FG (NCT00761059)
- Testing
- Glucose 20%, Aqua
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Cologne
Rupture of Fetal Membranes
Clinical Evaluation of the AmniSure ROM Test
To show that having less qualified personnel (non-Laboratory trained professionals) perform the test yields the same result as if a Laboratory trained professional performed the test.
- Trial name
- NCT01847820
- Testing
- AmniSure ROM test
- Where
- 4 sites in United States
- Volunteers
- 383 people
- Sponsor
- QIAGEN Gaithersburg, Inc
Premature Birth
Three-Part Program for Parents With Premature Infants
This study evaluated the efficacy of a comprehensive, three-part program for parents of premature infants. This program was designed to improve development in preterm children and includes an educational video, tests to evaluate…
- Trial name
- NCT00056680
- Testing
- Psychoeducational video, Infant massage, Brazelton Neonatal Behavioral Assessment Scale
- Where
- 5 sites in United States
- Volunteers
- 173 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hypotension
Avoiding Hypotension in Preterm Neonates
Objectives Firstly to examine in preterm neonates, whether it is possible to reduce number of hypotensive episodes and use of catecholamines by applying cerebral/peripheral near infrared spectroscopy in combination with…
- Trial name
- AHIP (NCT01910467)
- Testing
- NIRS visible and predefined interventions, NIRS not visible and treatment as usual
- Where
- Austria
- Volunteers
- 98 people
- Sponsor
- Medical University of Graz
Preterm Birth
The Effect Of Risk Factors Considered Together With Preterm Birth History on Development
This thesis was planned to examine the effects of risk factors seen with a history of preterm birth on sensory and motor development in preschool children.
- Trial name
- NCT05087511
- Testing
- motor and sensory development assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
Growth of Airways and Lung Tissues in Premature and Healthy Infants
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00419588
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Indiana University
Preterm Delivery, Neonatal Complications
Progestagens for the Tertiary Prophylaxis of Preterm Delivery
Objective: This trial would evaluate the clinical effectiveness of Progesterone(P) and 17-hydroxy Progesterone (17P) in reducing PTD, in symptomatic women at risk because of cervical shortening, in the present pregnancy.
- Trial name
- PROTECT (NCT01178788)
- Testing
- 17 alpha-hydroxy progesterone caproate, micronized Progesterone, Control
- Where
- Italy
- Volunteers
- 254 people
- Sponsor
- University of Modena and Reggio Emilia
Bronchopulmonary Dysplasia, Neurally Adjusted Ventilatory Assist
NAVA vs. CMV Crossover in Severe BPD
This prospective, unblinded, pilot randomized cross-over trial of 2 modes of mechanical ventilation will compare measures of pulmonary mechanics, respiratory gas exchange, and patient comfort between conventional flow triggered…
- Conditions
- Bronchopulmonary Dysplasia, Neurally Adjusted Ventilatory Assist, Mechanical Ventilation
- Trial name
- NCT04821453
- Testing
- NAVA, CMV
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Philadelphia
Mental Health Wellness 1, Preterm Birth
Reducing Pregnancy Risks: The Mastery Lifestyle Intervention
This randomized controlled trial will test an intervention called the Mastery Lifestyle Intervention (the MLI) that was developed from data of 1000+pregnant Hispanic women related to risks of preterm birth.
- Trial name
- MLI (NCT05012072)
- Testing
- The Mastery Lifestyle Intervention
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- Microgen LLC
Obstetric Labour, Premature
A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor
The study's primary objective is to demonstrate the superiority of retosiban to prolong pregnancy and improve neonatal outcomes compared with placebo.
- Trial name
- NEWBORN-1 (NCT02377466)
- Testing
- Retosiban IV infusion
- Where
- 50 sites in United States, Canada and 3 more
- Volunteers
- 25 people
- Sponsor
- GlaxoSmithKline
Growth
Preterm Infants Fed a Human Milk Fortifier
This is a double-blind, randomized, multi-center, controlled, parallel study to evaluate the growth and tolerance of preterm infants fed human milk fortifier (HMF).
- Trial name
- NCT05551975
- Testing
- Control Product, Experimental Product 1, Experimental Product 2
- Where
- 14 sites in United States
- Volunteers
- 321 people
- Sponsor
- Abbott Nutrition
PPROM, Preterm
Preterm Rupture of Membranes Optimising Antibiotics Trial
The goal of this clinical trial is to learn which antibiotic regimen works best to prevent infection in pregnant women whose waters break early (preterm, pre-labour rupture of membranes, or PPROM) and assess the health outcomes…
- Trial name
- PROMOAT (NCT06906757)
- Testing
- Erythromycin 250mg and Amoxicillin 500mg
- Volunteers
- 3,900 people
- Sponsor
- University of Melbourne
Premature Newborn, Nurse
The Effect of Massage, Wipe Bathing and Tub Bathing on Physiological Measurements of Late Premature Newborns
Purpose: This randomized experimental study aimed to analyze the effect of massage, wipe bathing and tub bathing of late premature newborns on their physiological measurements. Design and Methods: .
- Conditions
- Premature Newborn, Nurse, Physiological Measurements
- Trial name
- NCT04602130
- Testing
- Control, Massage, Sponge Bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Inonu University