Clinical trials: Premature Ejaculation
Premature Ejaculation
Dorsal Penile Nerve Cryoneurolysis for Lifelong PE
The goal of this clinical trial was to learn whether adding dorsal penile nerve cryoneurolysis to medication and behavioral therapy helps men with lifelong premature ejaculation.
- Trial name
- NCT07879105
- Testing
- Percutaneous Dorsal Penile Nerve Cryoneurolysis, Sertraline (Oral Antidepressant), Tadalafil 5 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Biruni University
Premature Ejaculation, Erectile Dysfunction
Observational Study of Pharmacological Treatment for Premature Ejaculation Concurrent With Erectile Dysfunction
Premature ejaculation (PE) is a common disease in the andrology clinic. Currently, the effectiveness and outcome differences of drug treatment still need to be studied and demonstrated.
- Trial name
- NCT04361305
- Testing
- Dapoxetine, Tadalafil
- Volunteers
- 150 people
- Sponsor
- Yan-Ping Huang
Premature (Early) Ejaculation, Ejaculatory Dysfunction
Extracorporeal Magnetic Innervation Plus Pelvic Floor Muscle Training for Premature Ejaculation
This single-center, prospective, parallel-group randomized controlled trial evaluated whether extracorporeal magnetic innervation (ExMI) added to pelvic floor muscle training (PFMT) improves pelvic floor muscle function and…
- Conditions
- Premature (Early) Ejaculation, Ejaculatory Dysfunction, Sexual Dysfunction Male
- Trial name
- NCT07385222
- Testing
- Pelvic Floor Muscle Training, Extracorporeal Magnetic Innervation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Abant Izzet Baysal University
Premature Ejaculation, Erectile Dysfunction
The Efficacy and Safety of Dapoxetine/Sildenafil Combination Therapy
The purpose of this study is to evaluate the efficacy and safety of Dapoxetine/Sildenafil 30/50 mg film-coated tablet in the treatment of men with premature ejaculation and erectile dysfunction.
- Trial name
- DAP-SPEED (NCT02939495)
- Testing
- Dapoxetine/Sildenafil 30/50 mg film coated tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
Ejaculatory Dysfunction, Premature Ejaculation
Ejaculatory and Orgasmic Dysfunction Registry
The goal of this observational study is to evaluate the safety and efficacy of various therapies used to treat ejaculatory and/or orgasmic dysfunctions in men.
- Conditions
- Ejaculatory Dysfunction, Premature Ejaculation, Delayed Ejaculation, Anorgasmia
- Trial name
- NCT06605469
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Premature Ejaculation
Evaluation of the Safety and Effectiveness of the vPatch Device
Multi-center, international, prospective, randomized, double-blind, two-arms, sham-controlled, first-in-human clinical investigation.
- Trial name
- NCT03942367
- Testing
- Active Device (vPatch)
- Where
- 3 sites in Israel, Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virility Medical Ltd.
Ejaculation
Assessment Of Safety Of UK-390,957
To determine whether UK-390,957 is a safe treatment for premature ejaculation.
- Trial name
- NCT00219609
- Testing
- UK-390,957
- Where
- 82 sites in United States, Australia and 12 more
- Volunteers
- 1,058 people
- Sponsor
- Pfizer
Premature Ejaculation
Discontinuation of Dapoxetine Treatment in Patients With Premature Ejaculation
Premature ejaculation (PE) has been known as one of the most common male sexual dysfunction. Until now dapoxetine is the only approved medical treatment option and there is no second line therapy in case of no-response or refuse…
- Trial name
- NCT03018743
- Testing
- Dapoxetine
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Pusan National University Hospital
Erectile Dysfunction, Sexual Dysfunction
Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction
The purpose of this study is to evaluate the efficacy and safety of dapoxetine compared to placebo in men with premature ejaculation and erectile dysfunction who are currently being treated with a phosphodiesterase-5 inhibitor…
- Trial name
- COUPLE (NCT01063855)
- Testing
- Dapoxetine, PDE5I (phosphodiesterase-5 inhibitor)
- Where
- 69 sites in United States, Argentina and 11 more
- Volunteers
- 495 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Obstetric Labour, Premature, Premature Ejaculation
A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.
A study conducted on healthy volunteers to determine the safety, tolerability and affect on the human body by experimental drug GSK557296.
- Trial name
- NCT00549211
- Testing
- GSK557296
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Effects of Proxelan Somministration in Patients With Chronic Prostatitis
The purpose of the study is to determinate the antinflammatory effects of the Proxelan on a cohort of patients affected by prostatitis'like symptoms and clinical evidence of abacterical prostatistis, trough a significative…
- Conditions
- Chronic Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Premature Ejaculation
- Trial name
- NCT03629769
- Testing
- Proxelan
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pisa
Premature Ejaculation
A Study On Concentrations Of 16448 In Blood And The Safety Of This Compound In Healthy Males With Premature Ejaculation
16448 is being investigated for the treatment of primary premature ejaculation (PE) using a novel mode of action. There are no approved therapies for premature ejaculation, and novel therapies are needed for this syndrome.
- Trial name
- NCT00537459
- Testing
- 16448
- Where
- Ireland
- Volunteers
- 18 people
- Sponsor
- GlaxoSmithKline
Premature Ejaculation, Ejaculation
Effect of Prostatic Urethra and Seminal Vesicle Morphometry on Ejaculation
The goal of this observational study is to learn whether the size and shape of the prostatic urethra and seminal vesicles - measured on multiparametric prostate MRI (mpMRI) - are related to premature ejaculation (PE) severity in…
- Trial name
- NCT07614854
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Premature Ejaculation
Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation
This study is designed to evaluate the efficacy and safety of DA-8031 and to decide the optimal dose of DA-8031 in male patients with premature ejaculation after oral administration on-demand.
- Trial name
- NCT01798667
- Testing
- DA-8031
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Sexual Dysfunction, Physiological, Ejaculation
An Observational Study of Men With Premature Ejaculation Who Are Treated With Dapoxetine Hydrochloride or Alternate Care Defined as Any Treatment Other Than Dapoxetine Hydrochloride
The purpose of the study is to collect information regarding the safety of dapoxetine hydrochloride when used in clinical practice to treat men with premature ejaculation.
- Trial name
- NCT01021670
- Testing
- Dapoxetine hydrochloride, Alternate care/non-dapoxetine hydrochloride treatment(s)
- Where
- 212 sites in Austria, Finland and 4 more
- Volunteers
- 10,027 people
- Sponsor
- Janssen Research & Development, LLC
Premature Ejaculation
Safety and Efficacy of Silodosin in the Treatment of Premature Ejaculation
The objectives of the present study aims to evaluate the safety and efficacy of Silodosin in a population of patients wih Premature Ejaculation (PE).
- Trial name
- NCT02581826
- Testing
- Silodosin
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Premature Ejaculation
Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation
The purpose of this study is to evaluate the effectiveness, safety and tolerability of the investigational drug, PSD502 in subjects with premature ejaculation (PE) The study drug, PSD02, is a metered dose (measured dose), topical…
- Trial name
- NCT00556478
- Testing
- PSD502, contains a mixture of lidocaine and prilocaine
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Plethora Solutions Ltd
Premature Ejaculation
A New Treatment for Premature Ejaculation?
The aim of study is to determine if they can produce increases in the IELT using a masturbator in subjects with premature ejaculation, producing improvements in the quality and satisfaction of the sexuality of the patient.
- Trial name
- NCT02297152
- Testing
- FLIP HOLE
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Instituto Sexológico Murciano
Erectile Dysfunction, Sexual Dysfunction
Erectile Dysfunction, Psychological Disorders, and Sexual Performance Among Men Seeking Medical Help for Fertility
According to the World Health Organization (WHO) and the World Association for Sexual Health (WAS), sexual health is directly related to everyone's mental health and quality of life.
- Conditions
- Erectile Dysfunction, Sexual Dysfunction, Premature Ejaculation, Infertile Men
- Trial name
- NCT04941690
- Testing
- A questionnaire method was used.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The First Hospital of Jilin University
Premature Ejaculation
Study to Evaluate Efficacy and Safety in Male Subjects With Premature Ejaculation
The purpose of this clinical trial is to test an experimental drug therapy called Tramadol Hydrochloride (HCl) Orally Disintegrating Tablets (ODT) ("Tramadol HCl ODT" or the "study drug").
- Trial name
- NCT00983736
- Testing
- Tramadol Hydrochloride
- Where
- 48 sites in Bulgaria, Czechia and 3 more
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.