Clinical trials: Prehabilitation, open to volunteers
End-stage Liver Disease, Liver Cirrhosis
Nutrition and Exercise Prehabilitation in Patients Awaiting Liver Transplantation
This study aims to evaluate the effects of a diet with even protein distribution plus exercise (Group A) versus a diet with skewed protein distribution plus exercise (Group B) versus standard dietary and physical activity advice…
- Conditions
- End-stage Liver Disease, Liver Cirrhosis, Liver Transplantation, Malnutrition
- Trial name
- POWER-LT (NCT07561138)
- Testing
- Diet with even protein distribution plus exercise program, Diet with skewed protein distribution plus exercise program, Standard dietary and physical activity advice
- Where
- 2 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Kalliopi Anna Poulia
Peripheral Arterial Disease
Prehabilitation and Rehabilitation in PAD
To determine the effectiveness of pre and post-operative exercise therapy in patients undergoing peripheral artery stenting for peripheral arterial disease.
- Trial name
- PREPARE-IT (NCT06566976)
- Testing
- Exercise Intervention, VAPAHCS Rehabilitation Core Components
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Palo Alto Veterans Institute for Research
Cancer Surgery
Prehabilitation to Improve Heart Rate Variability (PRIME)
Cancer patients require chronic management and care. For those individuals living with cancer, a comprehensive approach that acknowledges the interdisciplinary nature of their condition can help guide appropriate care strategies…
- Trial name
- PRIME (NCT06744413)
- Testing
- Multimodal prehabilitation program
- Where
- 4 sites in Italy
- Volunteers
- 600 people
- Sponsor
- Università Vita-Salute San Raffaele
Colorectal Cancer, Older Adults (60 - 85 Years Old)
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin.
- Conditions
- Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
- Trial name
- CHEMOBRAIN (NCT07341217)
- Testing
- Exercise Prehabilitation, Multivitamins, Standard Care (in control arm)
- Where
- 4 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Dr. Chris Gaffney
Pancreatic Cancer, Pancreatic Neoplasms
Wearable-Supported Prehabilitation and Rehabilitation for Patients Undergoing Surgery for Pancreatic Cancer
The goal of this clinical trial is to evaluate whether a wearable-enabled prehabilitation and rehabilitation pathway can improve recovery and post-operative outcomes in adults undergoing surgery for pancreatic cancer or related…
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Periampullary Carcinoma, Pancreatic Surgery
- Trial name
- POWR-PaC (NCT07772258)
- Testing
- Corsano CardioWatch, Prehab4Cancer Programme
- Volunteers
- 120 people
- Sponsor
- Manchester University NHS Foundation Trust
Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Feasibility and Utility of a Prehabilitation Program for Use in Patients With Benign Prostatic Hyperplasia Who Have Elected to Undergo Holmium Laser Enucleation of the Prostate (HoLEP).
Benign prostatic hyperplasia (BPH) is a debilitating condition which is highly prevalent in older males, up to 45% of those over the age of 45 are affected and 80% of those over the age of 70 are affected.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Outflow Obstruction
- Trial name
- NCT07552961
- Testing
- Comprehensive Prehabilitation Programming
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Multiple Myeloma
Evaluation of a PREHABilitation Protocol Using Adapted Physical Activity (APA) for Multiple Myeloma Patients Eligible for Intensive Autologous Stem Cell Transplantation Treatment
Adapted physical activity for patients with haematological malignancies generally has positive effects on quality of life, fatigue and physical condition. However, some studies show little or no effect.
- Trial name
- PREHAB-APA (NCT06789003)
- Testing
- Adapted exercises, No intervention, Quality of Life questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Bariatric Surgery Candidate, Obesity
The Effect of Exercise in Patients Awaiting Bariatric Surgery
The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery.
- Trial name
- BariPrehab (NCT05235945)
- Testing
- Online exercise intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Malignant Female Reproductive System Neoplasm
Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients
This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment [NST]) to improve function in stage III-IVA gynecologic cancer…
- Trial name
- NCT07608445
- Testing
- Educational Intervention, Goal Setting, Interview
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Breast Cancer, Breast Neoplasms
Feasibility of a Preoperative, Multimodal Lifestyle Intervention in Patients With Breastcancer
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last…
- Trial name
- APRIORI (NCT06266312)
- Testing
- A multimodal prehabilitation programme
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Maastricht University Medical Center
Rehabilitation, Rotator Cuff
Prehabilitation Before Surgery: A Strategy To Accelerate Recovery After Rotator Cuff Repair?
A rotator cuff tear is a structural injury to one or more tendons of the rotator cuff, ranging from degenerative changes to partial or complete tears.
- Conditions
- Rehabilitation, Rotator Cuff, Prehabilitation
- Trial name
- PREHAB (NCT07820592)
- Testing
- Prehabilitation
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Laura Castillo Vejar
Colorectal Cancer, Colorectal Neoplasms
PRIORITY-CONNECT 2 Trial
Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal…
- Trial name
- PC2 (NCT06976710)
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 31 sites in Australia
- Volunteers
- 564 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Knee Arthroplasty, Total
Impact of Exercise Access on Physio Outcomes Post Knee Replacement
To stay strong, patients should do some strength training at least twice a week. However arthritic pain can limit walking and activity. The wait for knee surgery can be long, which can lead to loss of muscle strength.
- Trial name
- KEMTAI (NCT07502040)
- Testing
- Kemtai Digital App, NHS standard care
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Lung Cancer, Surgery
Nutritional Therapy Enriched With Omega-3 in Patients With Lung Resection
The aim of this study is to analyze the effect of enriched formula with omega-3 in the 30-day incidence infection and inflammatory response following lung resection surgery in lung cancer patients.
- Trial name
- NCT06531460
- Testing
- Fish oil enteral supplementation, Fish oil oral supplementation, Enteral nutrition without fish oil
- Where
- Mexico
- Volunteers
- 310 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Kidney Transplantation, Frailty
Prehabilitation for Kidney Transplant Candidates
This interventional trial seeks to determine the feasibility of wearable sensors to provide data from patients while undergoing supervised exercise.
- Conditions
- Kidney Transplantation, Frailty, Chronic Kidney Insufficiency
- Trial name
- NCT06886256
- Testing
- Polar H10 Heart Rate Monitor, Empatica EmbracePlus, Apple Watch Ultra 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Methodist Hospital Research Institute
Surgery--Complications
Does Prehabilitation Improve Outcome in Coloncancer Surgery?
The study aims to find out if complications after surgery for large bowel (colon) cancer can be reduced or avoided in the most frail and elderly by letting them go through an exercise- and diet regime prior to the surgical…
- Trial name
- PRIO (NCT04199208)
- Testing
- Prehabilitation and Immunonutrition, Standard Care Arm
- Volunteers
- 160 people
- Sponsor
- Region Skane
Stomach Neoplasms, Neoadjuvant Therapy
Family-Supervised Prehabilitation to Reduce Postoperative Complications After Neoadjuvant Chemotherapy in Gastric Cancer
This study evaluates whether a family-supervised exercise-nutrition-psychology program can reduce complications after stomach-cancer surgery. Eligible patients are adults who will receive chemotherapy before surgery.
- Trial name
- NCT07183358
- Testing
- Family-supervised Multimodal Prehabilitation, Standard Care
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Locally Advanced Breast Cancer (LABC), Postoperative Inflammation
Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy
This study evaluates whether preoperative shoulder range-of-motion exercises influence postoperative inflammatory response, pain, shoulder function, and quality of life in patients with locally advanced breast cancer undergoing…
- Conditions
- Locally Advanced Breast Cancer (LABC), Postoperative Inflammation, Prehabilitation
- Trial name
- NCT07420335
- Testing
- Preoperative shoulder exercise, Standard preoperative care
- Where
- Indonesia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cardiovascular Diseases (CVD), Cardiovascular Surgery
The Effects of a 6-week Pre-operative Administration of a Microbiome Modulator "WellBiome" Versus Placebo on Cardiac Surgical Outcomes and NHS Cost Savings.
More than 7.4 million people in the UK are currently waiting for surgery. Behind that number are real people-patients preparing mentally and physically for procedures ranging from joint replacements to major heart and abdominal…
- Trial name
- NCT07483502
- Testing
- 5g of prebiotic fibre and 300mg of magnesium (WellBiome), 5g of maltodextrin
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Prehabilitation
Cognitive and Physical Optimization in Prevention of Postoperative Cognitive Deficit in Elderly With Lung Resection
Postoperative cognitive deficit and its connection with surgery and general anesthesia were first mentioned in the literature in 1955 by Bradford.
- Trial name
- COGNITION (NCT06339268)
- Testing
- Cognitive training, CogniFit App
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Military Medical Academy, Belgrade, Serbia