Clinical trials: Pregnancy Related
Heart Failure With Preserved Ejection Fraction (HFPEF)
Association of Heterogeneous Circulating Biomarkers and Anamnestic Factors of Pregnancy Adverse Course and Outcomes With the Prognosis of Heart Failure With Preserved Ejection Fraction
The primary purpose of this study is to evaluate possible association of some heterogeneous circulating biomarkers and anamnestic factors of pregnancy adverse course and outcomes with the prognosis of heart failure with preserved…
- Trial name
- CARPO-HF (NCT06803849)
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Endometrioma, Inflammation
Anti-inflammatory Markers in Endometrioma
Investigators aimed to measure the serum levels of adropin, salusin-α, netrin-1, and nesfatin-1, anti-inflammatory effects of which have been demonstrated previously, in endometriosis patients and to find out any association of…
- Trial name
- NCT04371133
- Testing
- Adropin (ng/L)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Overweight and Obesity, Weight Loss
PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Copenhagen
The study is a single site parallel randomized controlled study. The study will be assessing the effect of approximately 10% weight loss intervention vs a control group among healthy females/couples where the prospective mother…
- Conditions
- Overweight and Obesity, Weight Loss, Pregnancy Related
- Trial name
- PREPARE CHILD (NCT05621109)
- Testing
- Weight loss intervention
- Where
- Denmark
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Christian Mølgaard
Affective; Reaction, Pregnancy Related
Developing and Validating Digital Affective Patient Experience/Outcome Measure
The aim of the research project is to develop and validate a new digital measure of affective patient experience in maternal care.
- Conditions
- Affective; Reaction, Pregnancy Related, Validation Studies
- Trial name
- ETVa (NCT03337321)
- Where
- Finland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Twin; Pregnancy, Affecting Fetus or Newborn
Birth Weight-discordance in Twins Pregnancy: a Multicenter Retrospective Study
The rate of twin pregnancies in China has increased by 50 percent over the past decade and now stands at about 3 percent. This is significantly higher than the European and American countries.
- Trial name
- NCT05674214
- Where
- China
- Volunteers
- 13,440 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Ovarian Reserve, Endometrioma
Endometrioma Per se Versus Treatment Related Reduction in Ovarian Reserve (ERROR-2 Trial)
The present multi-center study aimed to evaluate whether endometrioma-associated decline in ovarian reserve is progressive in the absence of an intervention and is greater in magnitude than the natural decline over time.
- Trial name
- ERROR2 (NCT03620838)
- Testing
- oral contraceptive pill, oral progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Renal Cell Carcinoma (RCC)
Tertiary Lymphoid Structures Related Genes Predicting Prognosis in Clear Cell Renal Cell Carcinoma: a Retrospective Cohort Study
The purpose of this research was to uncover the prognostic significance of tertiary lymphoid structures related genes from ccRCC patients with respect to clinical characteristics and outcomes.
- Trial name
- NCT06883565
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Ding-Wei Ye
Preeclampsia
ECLAXIR:Search for an Association Between CX3CR1 V249I Polymorphism, Preeclampsia and Endothelial Injury
The study hypothesis is the involvement of the couple CX3CR1/CX3CL1 in occurrence of endothelial injury in preeclampsia. According to this hypothesis, Carriers of the I249 allele who express less CX3CR1 shoud be protected against…
- Trial name
- NCT00190177
- Where
- France
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Systolic Hypertension, Pregnancy Related
Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy
The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy.
- Conditions
- Systolic Hypertension, Pregnancy Related, Diastolic Hypertension, Cardiac Output, Low
- Trial name
- NCT04755764
- Testing
- Labetalol, Atenolol, Nifedipine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marshall University
Substance Abuse
Family Spirit Study
The goals of this study are to evaluate the effects of an in-home parenting education program, called Family Spirit, on parenting knowledge and skills and decreasing alcohol and substance use compared to a breast-feeding…
- Trial name
- NCT00356551
- Testing
- Family Spirit curriculum
- Where
- 5 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Kidney Disease, Hemodialysis Vascular Access
Transforming Hemodialysis-Related Vascular Access Education
The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis…
- Trial name
- THRiVE (NCT05997875)
- Testing
- Educational Materials, Motivational Interviewing, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 360 people
- Sponsor
- University of Pennsylvania
Anxiety, Depression
CALM for Pregnant and Post-Partum Women
Anxiety and depression is common along pregnant mothers and has been found to increase risk for negative outcomes in both mothers and infants.
- Conditions
- Anxiety, Depression, Depression, Postpartum, Pregnancy Related
- Trial name
- NCT03351465
- Testing
- Coordinated Anxiety Learning and Management
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Birth, First, Pregnancy Related
The Effect of the Continuous Midwifery Care Model on Birth Outcomes
It is the right of both the mother and her baby to receive the best care and give birth in the best way possible for every pregnant woman.
- Conditions
- Birth, First, Pregnancy Related, Newborn; Fit, Trauma, Psychological
- Trial name
- NCT06020339
- Testing
- The midwife-led continuous care model (MLCC)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tarsus University
HIV Infections, Cervix, Dysplasia
Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors
The purpose of this study is to see if it is safe and effective to give isotretinoin to HIV-infected women with cervical tumors to prevent these tumors from becoming cancerous.
- Trial name
- NCT00001073
- Testing
- Isotretinoin
- Where
- 40 sites in United States, Puerto Rico and 1 more
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Drug Abuse
Indirect Assessment and Intervention for Perinatal Drug Use
The purpose of this study is to assess the validity of an indirect computer-delivered screener for drug use and assess the efficacy of a computer-delivered brief intervention with urban post-partum women at-risk for substance…
- Trial name
- NCT01650675
- Testing
- WIDUS computer-delivered, indirect brief intervention
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Gestatiaonl Diabetes Mellitus, Early Pregnancy
Biomarkers for Early Screening of Gestational Diabetes Mellitus
Gestational Diabetes Mellitus (GDM) refers to the abnormal glucose metabolism first detected during pregnancy. It is estimated that approximately 7% of pregnant women worldwide and their offspring are affected by GDM.
- Trial name
- NCT05142020
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Gynecologic Neoplasms, Cognition Disorders
Emerging From the Haze for Gynecologic Cancer Survivors
At Cedars-Sinai Medical Center, the investigators have developed a novel curriculum for a 6-week psycho-educationally-based, cognitive behavioral program to help patients with subjective cognitive complaints after cancer…
- Trial name
- NCT02918461
- Testing
- Emerging from the Haze class
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cedars-Sinai Medical Center
Covid19
COVID-19 Pregnancy Related Immunological, Clinical and Epidemiological Factors and Perinatal Outcomes
This is a prospective cohort study of pregnant patients at an urban academic center diagnosed with perinatal COVID-19 infection, followed up to 6 weeks postpartum.
- Trial name
- COVID-PRICE (NCT04659759)
- Testing
- COVID-19 exposure, COVID-19 vaccine
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Thomas Jefferson University
Fibromuscular Dysplasia
Cohort Follow-up of Patients With Renal or Craniocervical Fibromuscular Dysplasia
PROFILE is a cohort study evaluating the progression of fibromuscular dysplasia lesions. This study is the prospective dimension of ARCADIA registry (ClinicalTrials.gov Identifier: NCT02884141), which aims to document phenotypic…
- Trial name
- PROFILE (NCT02961868)
- Testing
- Abdominal and supra-aortic trunks vascular imaging, Blood sampling (genetic), Blood sampling (biomarkers)
- Where
- 17 sites in Belgium, France
- Volunteers
- 340 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome, Infertility, Female
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue under Ultrasound Guidance in Women with Infertility due to Polycystic Ovary Syndrome
- Trial name
- NCT06206746
- Testing
- May Health System
- Where
- 19 sites in United States
- Volunteers
- 93 people
- Sponsor
- May Health
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