Clinical trials: Pregnancy Anemia
BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype
Study With Trabectedin in BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Ovarian Cancer
This is a multicenter phase II study on trabectedin in advanced or recurrent ovarian cancer patients with BRCA mutation and BRCAness phenotype.
- Trial name
- MITO15 (NCT01772979)
- Testing
- Trabectedin
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy
Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women
The clinical study aims to evaluate the effect of iron supplementation in preventing the onset of Iron Deficiency Anemia during pregnancy.
- Trial name
- NCT07884617
- Testing
- Iron plus folic acid, Folic acid
- Where
- Italy
- Volunteers
- 162 people
- Sponsor
- IBSA Farmaceutici Italia Srl
Anemia of Prematurity, Necrotizing Enterocolitis
Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates
Despite many advances in neonatal care, necrotizing enterocolitis (NEC) remains a leading cause of morbidity and mortality among premature infants.
- Trial name
- NCT01735552
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Postpartum Period
Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care
Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are…
- Trial name
- NCT06963047
- Testing
- Ultrasound, Standard care
- Where
- Israel
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Anaemia
4 Week Correction Study in Subjects With Anemia Associated With Chronic Kidney Disease Who Are Not Undergoing Dialysis
This is a four-week Phase IIa, randomized, double-blind, placebo-controlled, parallel-group, multi-center study to evaluate the safety, efficacy and pharmacokinetics of GSK1278863 in approximately 68 subjects with anemia…
- Trial name
- NCT01587898
- Testing
- GSK1278863
- Where
- 55 sites in United States, Canada and 1 more
- Volunteers
- 72 people
- Sponsor
- GlaxoSmithKline
Postpartum Hemorrhage, Uterine Atony
Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Trial name
- NCT02229513
- Testing
- Uterine Cooling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Renal Failure Chronic, Anemia
Predictors of Response to Iron and Erythropoietin Stimulating Agents
The purpose of the study is to identify predictors of treatment response. This involves collected baseline clinical parameters and bloods for biochemical parameters prior to administering the study treatment.
- Trial name
- PRIME (NCT03658876)
- Testing
- Iron Sucrose Solution for Injection, Epoetin Beta
- Volunteers
- 197 people
- Sponsor
- Imperial College London
Iron Deficiency Anaemia in Childbirth
EFFICACY OF IV VERSUS ORAL IRON IN THE TREATMENT OF IRON DEFICIENCY ANEMIA DURING PREGNANCY
This study was planned to compare outcomes of IV versus oral iron in the treatment of iron deficiency anemia during pregnancy. This study was used to investigate the efficacy of two new formulations of iron both in IV and oral…
- Trial name
- NCT07384663
- Testing
- Iron Carboxymaltose, Iron Polymaltose Complex
- Where
- Pakistan
- Volunteers
- 112 people
- Sponsor
- Dr Salaha Azam
Anemia, Renal Insufficiency, Chronic
A Prospective Interventional Study Assessing the Clinical and Operational Effectiveness of Transitioning From Mircera to Daprodustat for the Treatment of Anemia in End Stage Kidney Disease
Investigator-initiated, interventional, prospective study to assess the clinical and operational effectiveness of daprodustat in adult patients receiving in center hemodialysis or peritoneal home dialysis who are transitioning…
- Conditions
- Anemia, Renal Insufficiency, Chronic, Renal Anemia
- Trial name
- ROQ-IT (NCT05951192)
- Testing
- Daprodustat
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- USRC Kidney Research
Breast Cancer, Gynecologic Cancer
Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies
The main purpose of this study is to evaluate the impact of food supplements (herbal remedies) on sign and symptoms induced by cancer therapies: Nettle will be administered for improvement of anemia and fatigue; Peppermint will…
- Trial name
- GALENO 1 (NCT04474951)
- Testing
- Stinging Nettle, Peppermint
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic
Studies on Adsorption International Learning Initiative Global
Use of sorption technologies in patients undergoing maintenance hemodialysis with inflammatory syndrome and clinical manifestations of uremia
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic, Uremic; Toxemia, Inflammation Chronic
- Trial name
- SAILING (NCT07123909)
- Testing
- Patients will undergo a combined hemodialysis and hemosorption procedure. The study cartridge for hemosorption by Jafron HA130 contains the original adsorbing material.
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Botkin Hospital
Maternal Anemia in Pregnancy, Before Birth, Maternal; Malnutrition, Affecting Fetus
Maternal Under-nutrition and Effect of Amaranth Grain Flat-bread on Anemia
Introduction: In Ethiopia, maternal malnutrition is a severe public health issue. Underweight and anaemia are the two most common nutritional problems in pregnant women, and they often coexist.
- Trial name
- NCT06536153
- Testing
- Amaranth grain flat bread
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Hawassa University
Intrapartum - Moderate and Severe Anaemia
World Maternal Antifibrinolytic Trial_2
Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, almost all of which occur in low and middle income countries.
- Trial name
- WOMAN-2 (NCT03475342)
- Testing
- Tranexamic Acid
- Where
- 41 sites in Nigeria, Pakistan and 2 more
- Volunteers
- 15,068 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Sickle Cell Disease, Pregnancy, High Risk
TAPS2 Transfusion Antenatally in Pregnant Women With SCD
Sickle Cell Disease (SCD) is a serious inherited blood disorder affecting red blood cells. When oxygen levels drop the red cells become abnormally shaped and unable to move through the blood vessels easily.
- Conditions
- Sickle Cell Disease, Pregnancy, High Risk, Blood Transfusion Complication
- Trial name
- TAPS2 (NCT03975894)
- Testing
- Serial prophylactic exchange blood transfusion (SPEBT).
- Where
- 6 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Alpha Thalassemia Major, Hemoglobinopathy; With Thalassemia
In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)
The investigators aims to evaluate the safety of in utero hematopoietic stem cell transplantation in fetuses with alpha-thalassemia major performed at the time of in utero transfusion of red blood cells.
- Conditions
- Alpha Thalassemia Major, Hemoglobinopathy; With Thalassemia, Hemoglobinopathies, Fetal Anemia
- Trial name
- NCT02986698
- Testing
- in utero hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Francisco
Infant, Newborn, Infant, Low Birth Weight
The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants
This study tested the safety and efficacy of transfusing erythropoietin (Epo) and iron in infants of <1,250g birth weight. For infants 401-1,000g birth weight, we tested whether early erythropoietin (Epo) and iron therapy would…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- EPO (NCT01203514)
- Testing
- Erythropoietin
- Where
- 9 sites in United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Kidney Failure, Chronic, Anemia
Study of the Effect of Synchronised Anaemia Management in Chronic Kidney Disease
Aims: 1. To establish an electronic process for CKD anaemia management using monthly synchronized dosing of erythrocyte stimulating agents (ESA). 2.
- Trial name
- EMAN-Anaemia (NCT01763242)
- Testing
- EMAN
- Where
- Australia
- Volunteers
- 102 people
- Sponsor
- Western Health, Australia
Anemia
Evaluation of the Conversion From Peginesatide to Epoetin Alfa in Patients Receiving Hemodialysis
The purpose of this study is to evaluate whether hemodialysis patients on peginesatide can be converted to epoetin alfa by using a predefined conversion table while achieving a stable hemoglobin.
- Trial name
- NCT01737879
- Testing
- Peginesatide, Epoetin alfa
- Where
- 23 sites in United States
- Volunteers
- 41 people
- Sponsor
- Amgen
Iron Deficiency Anemia, Chronic Kidney Disease
Endovenous Versus Liposomal Iron in CKD
Anemia is a common complication in patients with chronic kidney disease (CKD). In addition to erythropoietin deficiency, many studies have identified iron deficiency as a cause of anemia in CKD patients.
- Trial name
- NCT01864161
- Testing
- gluconate iron, Liposomal iron
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Malaria
Intermittent Preventive Treatment During Pregnancy in Benin
Malaria in pregnancy is one of the most important preventable causes of low birthweight worlwide and a major cause of severe maternal anaemia contributing to maternal mortality.
- Trial name
- NCT00274235
- Testing
- sulfadoxine-pyrimethamine / mefloquine
- Where
- Benin
- Volunteers
- 1,600 people
- Sponsor
- Institut de Recherche pour le Developpement