Clinical trials: Pregestational Diabetes
Pregnancy, Pregestational Diabetes
Safety of Metformin in Pregnancy
This study aims to better characterize the risk linked to metformin use during pregnancy, using a prospective multicentric cohort design enabling a large sample size, in evaluating the rate of birth defects after first trimester…
- Conditions
- Pregnancy, Pregestational Diabetes, Polycystic Ovary Syndrom
- Trial name
- NCT02793505
- Testing
- metformin, any drug not known as a major teratogen or major fetotoxicant
- Volunteers
- 950 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Type 1 Diabetes (T1D), Pregnancy
Automated Insulin for Management of Intrapartum Glycemia
The goal of this clinical trial is learn if automated insulin delivery (AID) systems can be used for glucose management during labor/delivery for pregnant people with type 1 diabetes (T1D).
- Conditions
- Type 1 Diabetes (T1D), Pregnancy, Pre-Gestational Diabetes
- Trial name
- AIMING (NCT06883344)
- Testing
- Automated insulin delivery (AID) system, Intravenous (IV) insulin
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Pregestational Diabetes, Pregnancy
Once-Daily vs Twice-Daily Insulin Glargine in Pregestational Diabetes Management
The purpose of this study is to determine if taking insulin glargine twice a day instead of once a day will better manage pregestational diabetes in pregnant patients.
- Trial name
- NCT07224893
- Testing
- Use of insulin glargine once daily, Use of insulin glargine twice daily
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eastern Virginia Medical School
Type 1 Diabetes, Type 2 Diabetes
Comparison of Insulin Pump and MDI for Pregestational Diabetes During Pregnancy
This study is investigating whether insulin treatment with the insulin pump or with multiple daily injections (MDI) gives better outcomes for mother and baby in pregnant women with pregestational diabetes.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Pregnancy
- Trial name
- NCT02064023
- Testing
- insulin pump, multiple daily insulin injection
- Where
- 2 sites in Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Diabetes in Pregnancy
Telocytes in Placental Tissues of Patients With Gestational and Pre-gestational Diabetes
Examining the expression of telocytes in the placental tissues and umbilical cord of patients with gestational or pregestational diabetes during pregnancy compared to control.
- Trial name
- NCT05305326
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Gestational Diabetes, Diabetes
The Belgian Diabetes in Pregnancy Study: BEDIP-N Study
The General hypothesis is that the IADPSG screening strategy for gestational diabetes (GDM) will lead to an important increase in the work load and the prevalence of GDM in Belgium but that this might not be cost effective…
- Trial name
- BEDIP-N (NCT02036619)
- Where
- 7 sites in Belgium
- Volunteers
- 2,006 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gestational Diabetes, Pre-Gestational Diabetes
the Efficacy of Fetal Arterial and Venous Doppler Indices in Predicting Perinatal Outcome
To determine and evaluate the diagnostic performance of Doppler sonography of umbilical artery (UA), fetal middle cereberal artery (MCA), ductus venosus (VD) and umbilical vein (UV) for prediction of adverse perinatal outcome…
- Conditions
- Gestational Diabetes, Pre-Gestational Diabetes, IUGR, Macrosomia, Fetal
- Trial name
- NCT05410080
- Testing
- Fasting blood sugar, 2 hours postprandial, HBA1C ,Ultrasound and Doppler study
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Gestational Diabetes, Pregestational Diabetes
Permissive Intrapartum Glucose Control
The purpose of this study is to assess whether permissive intrapartum glycemic control compared to usual care would lead to similar rate of neonatal hypoglycemia among people with diabetes.
- Trial name
- NCT05553275
- Testing
- Usual Care, Permissive intrapartum glucose control
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pre-Gestational Diabetes, Type2diabetes
Successfully Achieving and Maintaining Euglycemia During Pregnancy for Type 2 Diabetes Through Technology and Coaching
The ACHIEVE RCT will measure the effect of the intervention (mHealth app with CGM, provider dashboard, and care team coaching) compared to current standard care (prenatal visits, self-monitored blood glucose, and certified…
- Conditions
- Pre-Gestational Diabetes, Type2diabetes, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT05662462
- Testing
- DEXCOM G7 PRO Continuous Glucose Monitor, Patient mHealth app linked to a provider dashboard, Care team coaching for medical and social needs (HUB)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Ohio State University
Diabetes Mellitus in Pregnancy
Efficacy of FGM in Pregestational Diabetes
Diabetes is the most common metabolic disease complicating pregnancy, and the number of women in childbearing age facing this problem is rising worldwide.
- Trial name
- FlashMom (NCT04666818)
- Testing
- Use of Flash Glucose Monitoring
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Catania
Gestational Diabetes Mellitus in Pregnancy, Pregestational Diabetes Mellitus
Intrapartum Glucose Control and Risk of Neonatal Hypoglycemia
The purpose of this study is to assess whether a liberal intrapartum glycemic target range compared to usual care standard control ranges will lead to a decrease in the rate of neonatal hypoglycemia among pregnant patients in…
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Pregestational Diabetes Mellitus, Neonatal Hypoglycemia
- Trial name
- NCT06643351
- Testing
- Standard Intrapartum Glucose Target Range, Liberalized Intrapartum Glucose Target Range
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- University of Pittsburgh
Pregnancy in Diabetics, Placenta
Fetal Growth and Placental Function in Pregnancies Complicated by Diabetes
Diabetic pregnancies are often complicated by placental dysfunction with reduced transfer of oxygen from the mother to the fetus, which may compromise fetal growth and organ development.
- Conditions
- Pregnancy in Diabetics, Placenta, Fetal Growth, Magnetic Resonance Imaging
- Trial name
- FaPDi (NCT04801121)
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sidsel Linneberg Rathcke