Clinical trials: Prediabetes
PreDiabetes
Effects of Allium Hookeri on Blood Glucose
The researchers investigated the anti-diabetic effects of Allium hookeri root extract for Korean prediabetic participants.
- Trial name
- NCT03330366
- Testing
- Allium hookeri extract
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Diabetes Mellitus, Type 2, Pre-diabetes
Models of Nutrition From Continuous Glucose Monitors
With this study, researchers want to conduct ambulatory studies in which people (healthy, with T2D, or at-risk of T2D) will consume a variety of pre-set and conventional meals in free-living conditions while wearing one or more…
- Conditions
- Diabetes Mellitus, Type 2, Pre-diabetes, Diet Habit, Diet, Healthy
- Trial name
- NCT04991142
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Polycystic Ovary Syndrome, Resistance, Insulin
Effects of Myo-inositol in Women With Polycystic Ovary Syndrome
The study will be carried out at the hospital of the medical school of sao paulo (HC-FMUSP) and the goal is to compare the effects of the administration of myo-inositol in relation to the effects of metformin in women with…
- Conditions
- Polycystic Ovary Syndrome, Resistance, Insulin, Glucose Intolerance
- Trial name
- NCT04892186
- Testing
- Myo-inositol, Metformin
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Heart Disease, Acute Coronary Syndrome
Acarbose Cardiovascular Evaluation Trial
The purpose of this study is to determine whether acarbose therapy can reduce cardiovascular-related morbidity and mortality in patients with impaired glucose tolerance (IGT) who have established coronary heart disease (CHD) or…
- Conditions
- Coronary Heart Disease, Acute Coronary Syndrome, Impaired Glucose Tolerance, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- ACE (NCT00829660)
- Testing
- Acarbose
- Where
- 177 sites in China, Hong Kong
- Volunteers
- 6,526 people
- Sponsor
- University of Oxford
Pre Diabetes, Weight Loss
Integrated Community-Clinical Linkage Model to Promote Weight Loss Among South Asians With Pre-Diabetes
The study "Integrated Community-Clinical Linkage Model to Promote Weight Loss among South Asians with Pre-Diabetes" is a two-arm randomized control trial that analyzes the implementation and effectiveness of a multi-component…
- Trial name
- NCT03188094
- Testing
- CHW-Led Health Coaching, EHR Alerts
- Where
- United States
- Volunteers
- 974 people
- Sponsor
- NYU Langone Health
Coronary Heart Disease Complicated With Impaired Glucose Tolerance
Can Platelets/Lymphocytes Rate Be New Serological Index for Prognosis of Coronary Heart Disease Complicated With Impaired Glucose Tolerance: Basic Principles and Experimental Design
Background About 2/3 patients of coronary heart disease (CHD) are complicated with disorder of carbohydrate metabolism which results in hyperglycemia and subsequent abnormality of coagulation system and inflammation.
- Trial name
- NCT02149056
- Testing
- observation, Impaired Glucose Tolerance
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Hebei University
Prediabetes, Metabolic Diseases
The Effects of Freshwater Clam Extract on Blood Sugar, and Lipid Profile in Prediabetes Patients
The purpose of this study is to determine whether the freshwater clam extract and its combination is effective on the improvement of glucose and lipid metabolism, also evaluate its ability to postpone prediabetes patients to…
- Conditions
- Prediabetes, Metabolic Diseases, Glucose Metabolism Disorders, Dietary Supplement
- Trial name
- NCT04429737
- Testing
- clam protein capsules, Clam peptide plus Chlorella capsules
- Where
- 2 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- Chang Gung Memorial Hospital
Healthy, Impaired Glucose Tolerance
Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability
The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors…
- Trial name
- NCT05493553
- Testing
- Dietary supplement regimen, Dietary supplement and intermittent fasting regimen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unicity International, Inc.
Diabetes, Prediabetes
Meta-analyses of the Effect of Dietary Pulses on Acute Postprandial Metabolic Control
Dietary pulses (beans, peas, chickpeas, and lentils), more commonly known as "legumes", are generally recognized as healthy components of the diet.
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01605422
- Testing
- Dietary pulses
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Diabetes Mellitus, Type 2
Nurse-led Continuum of Care for People With Diabetes and Pre-diabetes in Nepal
The study aims to improve diabetes prevention, access to care and advocacy through a novel cost-effective nurse-led continuum of care approach that incorporates diabetes prevention, awareness, screening and management for…
- Trial name
- NUCOD (NCT04131257)
- Testing
- Nurse-led Continuum of Care
- Volunteers
- 1,236 people, healthy volunteers welcome
- Sponsor
- Kathmandu University School of Medical Sciences
Obesity
Identification of Muscle-specific Biomarkers of Fatty Acid Beta-oxidation
Elevated fat levels within skeletal muscle cells (intramyocellular lipids) are highly correlated with muscle and whole-body insulin resistance, and more prevalent in obesity.
- Trial name
- FL-68 (NCT01494025)
- Testing
- Diet and Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Pre Diabetes
Asian Indian Prediabetes Study
Compared to other races, Indians have higher insulin resistance, poorer pancreatic function and a greater risk of developing diabetes, highlighting the importance of early strategies for improving insulin sensitivity and…
- Trial name
- AIPS (NCT04507685)
- Testing
- Lifestyle (Diet and Exercise)
- Where
- Singapore
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Pre Diabetes, Impaired Glucose Tolerance
Effect of F. Prausnitzii on Glycemic Control
The microbiota is associated with a wide spectrum of diseases including diabetes and non-alcoholic fatty liver disease. In this study we will investigate if the bacteria F.
- Conditions
- Pre Diabetes, Impaired Glucose Tolerance, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT04938843
- Testing
- F. prausnitzii and D. piger
- Where
- Sweden
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- MetaboGen AB
Pre Diabetes, Obesity
Community Based DPP Program for Hispanic/Latino Females
Is well known that obesity is increasing in the United States (US) and particularly among Hispanic/ especially in in socially disadvantaged groups.
- Trial name
- NCT04052815
- Testing
- Diabetes prevention program culturally tailored
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loyola University
PreDiabetes
Patient-centered Goal Setting in the National Diabetes Prevention Program
This is a cluster-randomized controlled trial of NDPP-Flex versus the standard NDPP to evaluate effects on glycemia, heterogeneity of treatment effects, and mechanisms of change.
- Trial name
- NDPP-Flex (NCT05559515)
- Testing
- NDPP-Flex, NDPP
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Denver Health and Hospital Authority
Glucose Intolerance
Carnitine Supplementation in Type 2 Diabetic Patients
the results from animal studies and preliminary human studies show that carnitine availability and acetylcarnitine concentrations are low in insulin resistant states such as with type 2 diabetes mellitus.
- Trial name
- NCT03230812
- Testing
- Carnitene (L-Carnitine or Levocarnitine)
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Maastricht University Medical Center
PreDiabetes, Type 2 Diabetes
Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep
The purpose of our study is to understand the impact of different meal timing alterations on blood sugars, metabolism, microbiome and sleep physiology in people with prediabetes and diabetes; and to study the temperature/heart…
- Conditions
- PreDiabetes, Type 2 Diabetes, Healthy
- Trial name
- NCT05413928
- Testing
- Time Restrictive Eating- late, Time Restrictive Eating- early, Time Restrictive Eating- early with early caloric intake
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Impaired Glucose Tolerance
Preliminary Safety and Efficacy Study of Extracellular Vesicle Infusion in the Intervention of Age-related Phenotypes With Impaired Glucose Tolerance.
The objective of this exploratory study was to evaluate the initial safety of human mesenchymal stem cell-derived extracellular vesicle infusion in an age-related phenotype with impaired glucose tolerance
- Trial name
- NCT06495437
- Testing
- Intravenous infusion of extracellular vesicle preparation derived from Wharton's jelly mesenchymal stem cells.
- Volunteers
- 20 people
- Sponsor
- BEAUTECH
Diabetes Mellitus
Prevent/Delay Development of Type 2 Diabetes in Subjects With Impaired Glucose Homeostasis Treated With Acarbose in Primary Care
The purpose of the study is to determine if the administration of small doses of Acarbose can prevent or delay the appearance of Type 2 Diabetes Mellitus in a population of subjects with prediabetes.
- Trial name
- NCT01010100
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- 23 sites in Spain
- Volunteers
- 204 people
- Sponsor
- Bayer
Impaired Glucose Tolerance, Cardiovascular Disease
The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial
The purpose of this study is to determine if ramipril and/or rosiglitazone prevent the onset of type 2 diabetes.
- Conditions
- Impaired Glucose Tolerance, Cardiovascular Disease, Glucose Metabolism Disorders
- Trial name
- NCT00095654
- Testing
- Ramipril, Rosiglitazone
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Gerstein, Hertzel, MD