Clinical trials: Prediabetes
Nutritional and Metabolic Diseases, Prediabetes
LIfestyle MEtabotype Study A
Glycemic responses vary significantly among individuals, even when consuming identical foods or meals, but the factors predicting individual glucose response to food intake remain poorly investigated.
- Conditions
- Nutritional and Metabolic Diseases, Prediabetes, Type 2 Diabetes
- Trial name
- LIME-A (NCT07868601)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Chronic Kidney Diseases, Hypertension
Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease
Real clinical practice register of Albuminuria detection in patients with previously undiagnosed chronic kidney disease
- Conditions
- Chronic Kidney Diseases, Hypertension, Chronic Heart Failure, Ischemic Heart Disease
- Trial name
- AURA (NCT05690009)
- Where
- Russia
- Volunteers
- 4,580 people
- Sponsor
- Eurasian Association of Therapists
Pre Diabetes
Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle?
Briefly, participants will be assessed for their eligibility for the study using an oral glucose tolerance test, which involves drinking a sugary drink followed by a series of small blood samples.
- Trial name
- NCT03804892
- Testing
- Body Composition, Maximal aerobic fitness test, Oral glucose tolerance test
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Liverpool John Moores University
Type 1 Diabetes (T1D), Pre Diabetes
INNODIA Family & Friends Early-Stage T1D Detection Protocol
The purpose of INNODIA DETECT is to identify people who are at increased risk of developing T1D. Investigators are doing this by testing for markers in the blood (autoantibodies) that tell them an individuals risk of getting T1D…
- Trial name
- INNODIA DETECT (NCT07118098)
- Where
- 21 sites in Austria, Belgium and 6 more
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- INNODIA iVZW
PreDiabetes, Circadian Dysregulation
Morning Light Treatment to Improve Glucose Metabolism
The primary purpose of this pilot study is to test a novel head worn light device (Re-Timer®) as an intervention to improve glucose metabolism in people with prediabetes.
- Trial name
- ML (NCT03188263)
- Testing
- Bright Light, Dim Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obesity, Pre-diabetes
SGLT2 Inhibitor Effects on Inflammation and Heart Disease in Obesity Pilot
Obesity is associated with increased cardiometabolic disease risk due, in part, to heightened chronic inflammation arising from adipose tissue.
- Trial name
- NCT04907214
- Testing
- Empagliflozin 25 MG
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Vanderbilt University Medical Center
Stroke Recurrence, Type 2 Diabetes
Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes
Objectives: This study aims to test whether a mobile app called PortionSize Ed can help adults who have had a recent stroke and also have prediabetes or type 2 diabetes improve their diet.
- Conditions
- Stroke Recurrence, Type 2 Diabetes, Prediabetes
- Trial name
- NCT07120334
- Testing
- PortionSize Ed + MedDiet Support, Standard of care for Stroke and Prediabetes or T2D
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Hawaii
Weight Loss, Blood Pressure
Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
This prospective study aims to assess the feasibility and implementation of a plant-based, weight-loss program in an office setting.
- Conditions
- Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes
- Trial name
- NCT04091516
- Testing
- Low-fat plant-based diet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Diabetes Mellitus, Glucose Intolerance
Prevalence of Glucose Intolerance and Risk Factors in Ethiopian Immigrants in Israel; Follow-up Study.
High risk population: Screening for impaired glucose tolerance.
- Trial name
- NCT01402362
- Where
- Israel
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Diabetes Mellitus Risk, PreDiabetes
The Impact of a Mobile Application Designed for Adults at Risk of Developing Diabetes
Aim: The aim of this study is to determine whether a prediabetes mobile application (PREDIABE-TR) designed in Turkish to inform and advise individuals at risk of developing diabetes about healthy eating and physical exercise can…
- Trial name
- MobileApp (NCT05592288)
- Testing
- PREDIABE-TR mobile app.
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Akdeniz University
PreDiabetes
Screening for Risk Factors of Prediabetes Among Adult Patients at Sohag University Hospital
Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above normal but below the diabetes threshold.. during the average 3 years of follow-up Prediabetes is diagnosed based on laboratory tests: fasting…
- Trial name
- NCT05864183
- Testing
- HbA1c, lipid profile, CBC
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Type 2 Diabetes, Muscular Atrophy
Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
The purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest in older adults with pre-diabetes and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise
- Trial name
- RECOVER (NCT04057677)
- Testing
- Bed Rest Intervention, Exercise Program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Diabetes, Metabolic Diseases
The Fasting II Study
This study will determine whether an intensive fasting protocol alters hemoglobin A1c measurements or other markers of metabolic and cardiovascular risk by performing a 5-week clinical trial of fasting among 12 pre-diabetic…
- Trial name
- NCT01792986
- Testing
- water-only 24-hour fasting once per week for 6 weeks
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intermountain Health Care, Inc.
Overweight, Obesity
Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)
Type 2 diabetes and prediabetes, which are mainly caused by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obesity, Type 2 Diabetes, Prediabetes
- Trial name
- SHAPE3 (NCT00928005)
- Testing
- Weight loss diet, Weight loss diet plus exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Type 2 Diabetes, PreDiabetes
Effect of Selenium Supplementation on Glycemic Control in Patients With Type 2 Diabetes or Prediabetes
Although it has been suggested that selenium (Se) increases the risk of T2DM, most evidence comes from observational studies that cannot prove causality.
- Trial name
- NCT05320510
- Testing
- Se-yeast
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Diabetes Mellitus, Type 2, Prediabetic State
Finding the Patient's Voice Diabetes Prevention Programs
This study uses patient engagement to develop a diabetes prevention program focused on adolescents and families.
- Trial name
- NCT02700503
- Testing
- Encourage 2.0
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Indiana University
Prediabetic State
Pilot Stair Climbing Study
This pilot study seeks to demonstrate feasibility to conduct data collection and illustrate potential for effect of fractionalized bouts of stair climbing on glucose control in adults at risk for type 2 diabetes.
- Trial name
- NCT02827383
- Testing
- Stair Climbing Frequency
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jennifer Gay
Food Insecurities, Cardiometabolic Comorbidities
Human Immunodeficiency Virus (HIV) Food Insecurities
The objectives of this study are to better understand how FI (food insecurities) contributes to the development of cardiometabolic comorbidities among PWH (People with HIV) and to test a novel bilingual FI intervention designed…
- Conditions
- Food Insecurities, Cardiometabolic Comorbidities, HIV, PreDiabetes
- Trial name
- NCT04943861
- Testing
- weCare/Secure, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University Health Sciences
Vitamin D Deficiency, Glucose Intolerance
Impact of Correction of Vitamin D Deficiency in Oxidative Stress in Patients With Prediabetes (VICOX)
The investigators aim to determine the effect of the correction of vitamin D in vitamin D deficient patients (<15ng/ml) in oxidative stress and insulin resistance in patients with impaired glucose tolerance.
- Conditions
- Vitamin D Deficiency, Glucose Intolerance, Oxidative Stress, Insulin Resistance
- Trial name
- VICOX (NCT03356873)
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 31 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Prediabetes
Exploring Unconventional Plant-Derived Metabolites for Glycemic Control: the Case of Pomegranate
The EXPLORER study will investigate whether supplementation with a pomegranate extract rich in ellagitannins is able to improve well-being and metabolic health in individuals without diabetes.
- Trial name
- EXPLORER (NCT06659523)
- Testing
- EPS supplement intervention
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Regina Menezes