Clinical trials: Pre-operative Assessment, open to volunteers
Head and Neck Cancer
A Phase II Study to Evaluate the Efficacy and Safety of Salvage Preoperative PD-1 Inhibitor Combined with Chemotherapy Neoadjuvant Therapy in Recurrent and Metastatic LPSCC/HPSCC
A prospective, multicenter, randomized controlled phase II study; Patients who met the inclusion criteria were divided into groups according to whether they had received radical radiotherapy or postoperative radiotherapy in the…
- Trial name
- NCT06793761
- Testing
- Pembrolizumab, Cisplatin, Nab-paclitaxel
- Volunteers
- 260 people
- Sponsor
- Beijing Tongren Hospital
Hormone Receptor Positive HER-2 Negative Breast Cancer
Impact of Endocrine Therapy, Menstrual Cycle, PAM50, Ki67 on Treatment Decisions in HR+ and HER2- Breast Cancer
PEAK is a prospective, multicenter, non-interventional investigator-initiated trial (IIT) that aims to investigate the influence of the menstrual cycle phase on Ki67 in patients who either receive Tamoxifen, Aromatase inhibitors…
- Trial name
- NCT05878314
- Where
- Germany
- Volunteers
- 504 people
- Sponsor
- University Hospital Tuebingen
Anxiety
The Assessment of Preoperative Anxiety in Cancer Patients: Validation, Observational, Descriptive Study.
The study stems from the need to have available effective tools for detecting the anxiety of the cancer patient who has to undergo surgery.
- Trial name
- V-ANXIETY (NCT07517458)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia
Ride-On Toy Car Use During Operating Room Transfer in Preschool Children
The goal of this clinical trial is to determine whether the method of transfer to the operating room can reduce preoperative anxiety and postoperative emergence delirium in male children aged 3 to 7 years undergoing elective…
- Trial name
- NCT07403747
- Testing
- Toy car, Standard Transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain, Laparoscopic Cholecystectomy
Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy
This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid…
- Trial name
- NCT07653490
- Testing
- Erector Spinae Plane Block, Low Fresh Gas Flow (0.5 L/min), Standard Fresh Gas Flow (3 L/min)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Perioperative Cardiovascular Risk, Postoperative Complications (Cardiopulmonary)
AI-ECG for Preoperative Cardiovascular Risk Stratification Before General Surgery
This randomized controlled trial evaluates whether an artificial intelligence-enhanced electrocardiography (AI-ECG)-based strategy for preoperative cardiovascular risk stratification is noninferior to usual care in patients…
- Conditions
- Perioperative Cardiovascular Risk, Postoperative Complications (Cardiopulmonary), Preoperative Care
- Trial name
- NCT07774689
- Testing
- AI-ECG-based preoperative risk stratification (ECG Buddy)
- Where
- South Korea
- Volunteers
- 3,200 people
- Sponsor
- Seoul National University Bundang Hospital
Elective Surgery, Frail Elderly
Hybrid III Trial of Automated Referral to Comprehensive Geriatric Assessment for Frail Older Surgical Patients
The goal of this observational study is to learn about automated referrals to Perioperative Optimization of Senior Health (POSH).
- Trial name
- NCT07836959
- Testing
- Automated referral, Usual Care Group
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Wisconsin, Madison
Awareness, Anesthesia
Anesthesia Awareness on YouTube: Content and Quality Analysis
This study aims to evaluate the quality and reliability of YouTube videos related to "anesthesia awareness." Using the search terms "anesthesia awareness" and "waking up during surgery," the first 100 videos from each search…
- Trial name
- NCT07323537
- Volunteers
- 200 people
- Sponsor
- Mentese State Hospital
Breast Cancer, Early-stage Breast Cancer
SABER Study for Selected Early Stage Breast Cancer
The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.
- Trial name
- SABER (NCT04360330)
- Testing
- Stereotactic Ablative Breast Radiotherapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Radar, Surgical Procedures, Operative
Millimeter Wave Radar-Based Non-Contact Cardiac Function Monitoring
This research will develop and clinically validate a system that enables continuous and non-invasive monitoring of cardiac function in surgical patients during the pre- and post-operative periods using contactless radar sensor…
- Trial name
- NCT07684222
- Testing
- Radar-based non-contact cardiac function monitoring.
- Volunteers
- 30 people
- Sponsor
- Rukiye Kokkiz
Delayed Gastric Emptying, Diabetes Mellitus
HbA1c Levels and Gastric Emptying Assessed by Gastric Ultrasound
Delayed gastric emptying increases the risk of pulmonary aspiration during general anesthesia. Diabetes mellitus and poor long-term glycemic control have been associated with impaired gastric motility.
- Conditions
- Delayed Gastric Emptying, Diabetes Mellitus, Pulmonary Aspiration
- Trial name
- NCT07375680
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Kutahya Health Sciences University
Head and Neck Cancer, Healthy
Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Multispectral Optoacoustic Tomography (MSOT) is a promising imaging technology that utilizes pulsed laser light. One of the key capabilities of this technology is measuring oxygenation within human tissue.
- Trial name
- msotcmfflap (NCT06716892)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Iron Deficiencies, Iron Deficiency Anaemia
Iron-deficiency Anaemia and Its Impact on Recovery After Colorectal Cancer Surgery
The aim of this prospective, observational cohort study is to assess the impact of iron deficiency anaemia on the incidence of perioperative complications and the quality of recovery after surgery in patients undergoing…
- Conditions
- Iron Deficiencies, Iron Deficiency Anaemia, Postoperative Complications, Colorectal Cancer
- Trial name
- ID-COLO (NCT06276140)
- Testing
- Laboratory analyses for the detection of iron deficiency anaemia
- Where
- Serbia
- Volunteers
- 200 people
- Sponsor
- Oncology Institute of Vojvodina
Incisional Hernia Repair, Ventral Hernia Repair
Comparative Evaluation of Preoperative Preparation Methods in Patients With Large Incisional Hernias
Patients with large, complex, or giant incisional hernias often require advanced preoperative optimization to facilitate safe abdominal wall reconstruction and reduce postoperative complications.
- Trial name
- AWR-PREP (NCT07549113)
- Testing
- Botulinum Toxin A (Botox ), Progressive Preoperative Pneumoperitoneum, Combined Preoperative Preparation
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital