Clinical trials: Pre-eclampsia
Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
Insulin Resistance and Hypertensive Disorders in Pregnancy
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester.
- Trial name
- NCT00412230
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Messina
Preeclampsia
Serum Markers in Preeclamptic Women
Could possible markers in serum obtained in the first trimester predict the human-pregnancy specific disorder pre-eclampsia?
- Trial name
- NCT01361737
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Preeclampsia
LMWH to Prevent Preeclampsia and Fetal Growth Restriction
The objective of this trial will be to determine whether prophylactic low-molecular weight heparin therapy in pregnant women with the heterozygous Factor V Leiden and G20210A prothrombin gene mutations thrombophilia and a history…
- Trial name
- NCT00260520
- Testing
- Dalteparin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florence
Preeclampsia, Preterm Birth
Biobank on Prematurity, Preeclampsia and Other Pregnancy Complications
The Biobank includes data and biological specimens of women from three original studies: 1) First-trimester Prediction of Preeclampsia (PREDICTION Study, NCT02189148), 2) Pre-Eclampsia And growth Retardation, an evaluative…
- Conditions
- Preeclampsia, Preterm Birth, Pregnancy Complications, Fetal Anomalies
- Trial name
- NCT02744365
- Testing
- Observational
- Where
- Canada
- Volunteers
- 7,845 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Preeclampsia, Heart Failure Preserved Ejection Fraction
Exercise Testing After Preeclampsia
Though cardiovascular disease (CVD) is the leading cause of mortality in women, traditional epidemiology in this area has focused on later life, when cardiometabolic risk has already exacted a cumulative toll on the vascular…
- Conditions
- Preeclampsia, Heart Failure Preserved Ejection Fraction, Hypertension
- Trial name
- NCT06741436
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Preeclampsia, Eclampsia
uChek Pilot Study for Urinalysis in the Antenatal Care Setting
A prospective observational study to test the feasibility of smartphone enabled uChek urinalysis device to detect biomarkers (protein, microalbumin and protein:creatine ratio) in urine, indicative of preeclampsia/eclampsia at…
- Conditions
- Preeclampsia, Eclampsia, Pregnancy, Proteinuria
- Trial name
- uChekBangla (NCT02256995)
- Testing
- uChek
- Where
- Bangladesh
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Maternova Research
Pre-Eclampsia, Intrauterine Growth Restriction
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a…
- Conditions
- Pre-Eclampsia, Intrauterine Growth Restriction, Polycystic Ovary Syndrome, Iron-deficiency
- Trial name
- NCT06115122
- Testing
- Pre-eclampsia screening program
- Where
- Finland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Pregnancy
Education and Counseling Program on Pregnant Women With Risk of Preeclampsia
The aim of the study is to evaluate the effect of education and counseling program on healthy lifestyle behaviors, self-efficacy and maternal/neonatal consequences of pregnant women with risk of preeclampsia.
- Trial name
- NCT04036786
- Testing
- study group, standard care
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Preeclampsia, Gestational Diabetes
The Association Between High Risk Pregnancy and Sleep-disordered Breathing
The aim of the present study is to establish, using polysomnographic criteria and prospective nature, whether sleep apnea in pregnancy is more prevalent in women with high risk pregnancies including preeclampsia, gestational…
- Conditions
- Preeclampsia, Gestational Diabetes, Premature Labor
- Trial name
- NCT01022619
- Where
- 2 sites in Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Pre-Eclampsia
The Effectiveness of Aspirin on Preventing Pre-eclampsia
This study will explore the effectiveness of low-dose aspirin on preventing pre-eclampsia in high-risks pregnant women by comparing the incidence of pre-eclampsia and pregnancy outcomes.
- Trial name
- NCT04656665
- Testing
- Aspirin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Preeclampsia, Pregnancy Related
Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients
This will be a randomized, open-label, controlled trial of patients at high risk of developing preeclampsia examining 81 mg/day vs 162mg/day daily acetylsalicylic acid (ASA) use.
- Trial name
- NCT05514847
- Testing
- Aspirin 81Mg Ec Tab, Aspirin 162Mg Ec Tab
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pregnancy Related, Pregnancy Disease
Fetal Autonomic Nervous sysTem Evaluation
The autonomic nervous system (ANS) is involved in cardiovascular, metabolic and cognitive processes, so its study in the fetus can provide relevant functional diagnostic and prognostic information.
- Conditions
- Pregnancy Related, Pregnancy Disease, Pregnancy Complications, Pre-Eclampsia
- Trial name
- FANTE (NCT06330987)
- Testing
- electrocardiograph
- Where
- Italy
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Pre-Eclampsia
First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler Angiography
Introduction: Preeclampsia (PE) and intrauterine growth restriction (IUGR) are two major pregnancy complications, related to a chronic utero-placental hypoperfusion.
- Trial name
- SPIRIT (NCT03342014)
- Testing
- Ultrasound, Blood sample collection
- Where
- France
- Volunteers
- 2,159 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Preeclampsia
Safety, Tolerability, and PK/PD of Telpegfilgrastim Injection in Non-pregnant Females of Childbearing
This is an open-label, single-arm, Phase Ⅰa clinical study designed to evaluate the safety, tolerability, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of multiple doses of Telpegfilgrastim Injection in non-pregnant…
- Trial name
- NCT06924385
- Testing
- Telpegfilgrastim Injection
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Xiamen Amoytop Biotech Co., Ltd.
Preeclampsia
Predicitve Use of Spot Urine Protein/Creatinine Ratios in Preeclampsia
The investigators intend to perform a large prospective study looking at the predictability of the random urine protein-to-creatinine ratio compared to the gold standard 24-hour urine protein collection.
- Trial name
- NCT00870428
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Postpartum Hemorrhage, Postpartum Preeclampsia
Postpartum Video Education
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression
- Trial name
- NCT05159726
- Testing
- Video Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Arterial Stiffness, Fetal Growth Retardation
Bioimpedence and Arterial Function Monitoring at Birth and in Infants
Babies may be born appropriately grown for gestational age (AGA, >10th centile) or small for gestational age (SGA, <10th centile).
- Conditions
- Arterial Stiffness, Fetal Growth Retardation, Small for Gestational Age at Delivery, Pre-Eclampsia
- Trial name
- BAMBI (NCT04720690)
- Testing
- Vicorder: pulse wave velocity, pulse wave analysis, stroke volume, cardiac output, NICaS, Echocardiography and ultrasound of arteries
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Hypertension, Pregnancy Induced, Preeclampsia
Blood Pressure Variability Effect on Right Ventricular Strain in Women With Hypertensive Disorders With Pregnancy
The goal of this observational study is to learn about the potential effect of blood pressure variability changes on right ventricular strain in pregnant women with gestational hypertension or pre-eclampsia
- Trial name
- NCT06100484
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aswan University
Preeclampsia and Eclampsia, Stiffness, Aortic
Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic Women After Delivery
The investigator measured the arterial stiffness using cardio-ankle vascular index (CAVI) test in patient with preeclampsia and normal pregnant women to evaluate the longitudinal change of CAVI and their predictors.
- Conditions
- Preeclampsia and Eclampsia, Stiffness, Aortic, Blood Pressure
- Trial name
- NCT04142268
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypertension, Pregnancy
Measuring Blood Pressure in Pregnancy Using Mercury and Automated Device
The aim of the PRAM study was to determine whether women diagnosed with hypertension in pregnancy, using the traditional mercury device, have the same pregnancy outcomes when blood pressure is measured by either an automated…
- Conditions
- Hypertension, Pregnancy, Pre Eclampsia
- Trial name
- PRAM (NCT00809666)
- Testing
- Automated blood pressure recording device Omron HEM 705CP
- Where
- Australia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- St George Hospital, Australia