Clinical trials: Pre-Frailty
Weak; Senile, Old Age; Debility
Comparison of the Functional Status, Psychosocial Aspects and Discharge Locations of Geriatric Patients Before and After Inpatient Geriatric Rehabilitation
Due to demographic change in Switzerland, the proportion of older people in the population is expected to increase. It is therefore important that people in old age remain in the best of health and maintain their independence for…
- Conditions
- Weak; Senile, Old Age; Debility, Movement Disorders, Quality of Life
- Trial name
- NCT07131865
- Where
- Switzerland
- Volunteers
- 753 people
- Sponsor
- University of Bern
Frail Elderly Syndrome
A Health Promotion Program to Prevent Frailty and Improve Frailty Status Among Pre-frail Elderly: Frailty Intervention Through Nutrition Education and Exercises.
Prevention of frailty is a major concern in geriatrics due to its high prevalence and various adverse health outcomes among elderly population.
- Trial name
- FINE (NCT04327544)
- Testing
- Frailty Intervention
- Where
- Malaysia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Cirrhosis, Liver
Comparison of the Effect of Two Interventions on Liver Frailty Index in Pre-frail and Frail Cirrhotic Patients Enlisted for Liver Transplantation
The goal of this prospective, double blind randomized clinical trial is to compare the effectiveness of two interventions in improve frailty (measured by Liver Frailty Index) and quality of life (measured by Chronic Liver Disease…
- Trial name
- NCT06149026
- Testing
- Physical and nutritional therapy
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Arthritis, Cancer
MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.
Sufficient muscle strength helps to get out of a chair and can prevent falls. Up to 30% of older adults experience age-related loss of muscle strength, which can lead to frailty and health instability.
- Conditions
- Arthritis, Cancer, Cardiovascular Diseases, Chronic Lung Disease
- Trial name
- NCT04663685
- Testing
- Exercise program, Nutrition education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Cognitive Dysfunction
Use of Electrophysiological Markers to Predict Post-operative Cognitive Dysfunction
As the population ages and medical progress is made, many elderly patients that previously would not have been candidates for surgery are now undergoing operations.
- Trial name
- NCT04512989
- Testing
- Cognitive assesment using MOCA test
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Frailty, Surgery--Complications
The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty
This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery.
- Conditions
- Frailty, Surgery--Complications, Disability Physical
- Trial name
- NCT04221295
- Testing
- Exercise Group
- Where
- Canada
- Volunteers
- 850 people
- Sponsor
- Ottawa Hospital Research Institute
Aging
Clinical Trial to Evaluate the Potential Efficacy and Safety of Human Umbilical Cord Blood and Plasma
This study aims to carry out a safety evaluation of human cord blood and frozen plasma as treatment for pre-frailty , to assess whether the treatment can prevent and improve the aging process, and to identify useful clinical…
- Trial name
- NCT02418013
- Testing
- Fresh cord blood(experimental group A), Frozen cord blood(experimental group B), Frozen plasma(experimental group C)
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Bundang CHA Hospital
Protein Metabolism
Peanut Sip Feeding Protocol
Peanuts are considered a functional food and regular consumption is associated with positive health effects. Protein is the second most common nutrient in peanuts after fat.
- Trial name
- NCT06693544
- Testing
- Peanut protein
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Frailty
Intervention for Pre-Frailty and Frailty in Thoracic Surgery Patients
Frailty has been associated with poor acute and long-term outcomes after major surgery. We recently determined that nearly 70% of patients undergoing major thoracic surgery are pre-frail or frail.
- Trial name
- NCT02522533
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Bladder Cancer, Bladder Neoplasm
Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct)
A bicentric, open-label randomised controlled trial (RCT) is planned to investigate whether the use of fitness wristbands in a defined preoperative period prior to radical cystectomy leads to a preoperative increase in…
- Conditions
- Bladder Cancer, Bladder Neoplasm, Bladder Urothelial Carcinoma
- Trial name
- PreAct (NCT06416319)
- Testing
- Daily Activity Goal and Feedback
- Where
- 2 sites in Germany
- Volunteers
- 164 people
- Sponsor
- Universitätsmedizin Mannheim
Frail Elderly Syndrome
Effectiveness of a Socio-Community Health Intervention on Pre-Frailty in Older Adults
The objective of this study is: To evaluate the effectiveness of a health intervention with a socio-community approach on frailty in older adults with pre-frailty.
- Trial name
- NCT06663150
- Testing
- health intervention with a socio-community approach
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Keralty SAS. Colombia
Frailty, Pre-Frailty
In-Person, Online, and Hybrid Healthy-Aging Education for Pre-Frailty and Frailty in Older Adults
The goal of this clinical trial is to determine whether a 6-month healthy-aging education program delivered in person, online, or in a hybrid format reduces frailty and is cost-effective compared with usual care in…
- Trial name
- FRAGSALUD-ON (NCT07738393)
- Testing
- In-person healthy aging education program, Hybrid healthy aging education program, Online healthy aging education program
- Where
- Spain
- Volunteers
- 276 people
- Sponsor
- University of Cadiz
Frailty, Inflammation
Reducing Frailty for Older Cancer Survivors Using Supplements
The purpose of the study is to examine the feasibility and safety of twelve weeks oral supplementation of Epigallocatechin-3-gallate (EGCG) in older survivors of cancer
- Trial name
- ReFOCUS1 (NCT04553666)
- Testing
- Epigallocatechin-3-Gallate (EGCG) plus Ascorbic Acid (Vitamin C)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Rochester
Pre-frail Elderly
Effects of Metformin in Pre-frail Elderly
The purpose of this study is to investigate the effects of metformin to prevent frailty in pre-frail non-diabetic elderly. Several outcomes measured in this study are frailty status, quality of life, handgrip strength, gait…
- Trial name
- NCT02325245
- Testing
- Metformin
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Indonesia
Pathologic Processes
Mesenchymal Stem Cells for Frailty Syndrome
This Phase I/II study is designed to evaluate the efficacy and safety of UMC119-06-05, an allogeneic umbilical cord mesenchymal stem cells, in older adults with frailty syndrome.
- Trial name
- NCT06501066
- Testing
- umbilical cord mesenchymal stem cells
- Where
- 2 sites in Taiwan
- Volunteers
- 66 people
- Sponsor
- Meribank Biotech Co., Ltd.
Frailty, Frail Elderly Syndrome
Effect of Baduanjin on Functional Performance in Pre-Frail/Frail Older Adults
The aim for this study is to investigate the effectiveness of a 16-week realistic community-delivered Baduanjin training program compared to a waitlist control intervention, in improving functional outcomes among pre-frail and…
- Trial name
- NCT04549103
- Testing
- Baduanjin exercise program
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- Geriatric Education and Research Institute
Geriatric Diseases
Increased Focus on Protein Intake Among Geriatric Patients
Up to approximately 38 (unknown drop-out rate) geriatric patients (at least 65 years old) are recruited from a Geriatric ward at Slagelse Sygehus.
- Trial name
- NCT03075189
- Testing
- Whey protein supplement
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University of Copenhagen