Clinical trials: Pre-Eclampsia
Pre-Eclampsia
Maternal and Neonatal Outcome in Severe Preeclampsia
In normal pregnancy the spiral arteries in the placental bed are invaded by trophoblast, which becomes incorporated into the vessel wall and replaces the endothelium, muscular layer and neural tissue
- Trial name
- NCT04126122
- Testing
- Ultrasonography to assess fetus and mother
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Preeclampsia, Pregnant With Complication
Feasibility of a Telemonitoring Program for Pregnant Women at High-Risk for Preeclampsia in Pakistan
High maternal mortality from preeclampsia/eclampsia results from a lack of early identification and management of pregnant women at high risk for preeclampsia.
- Trial name
- NCT05662696
- Testing
- Raabta Telemonitoring Program (Mobile Application)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Pre-eclampsia
Investigating the Novel Observation of Right-left Difference in Uterine Artery Vascular Resistance in Pre-eclampsia
The investigators previously demonstrated that epidural ropivacaine reduces uterine artery vascular resistance in a dose dependent manner in pre-eclampsia.
- Trial name
- NCT00848679
- Testing
- Epidural lidocaine, Epidural lidocaine 2%
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Preeclampsia
Family Study on Preeclampsia
This study will examine a possible genetic basis for preeclampsia, a disorder of high blood pressure and protein in the urine during pregnancy. Preeclampsia is a major pregnancy complication affecting both mother and baby.
- Trial name
- NCT00344162
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hypertension
Prevention of Severe Postpartum Hypertension
The purpose of this study is to determine whether postpartum administration of furosemide to women with antepartum hypertensive disorders (gestational hypertension, preeclampsia) or elevated blood pressure in the first 24 hours…
- Trial name
- NCT02450773
- Testing
- Furosemide, Potassium chloride
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Hypertension in Pregnancy, Pre-Eclampsia
Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy
The purpose of this research is to study digital health interventions to prevent cardiovascular disease in individuals who have had a hypertensive disorder of pregnancy (HDP).
- Conditions
- Hypertension in Pregnancy, Pre-Eclampsia, Eclampsia, Gestational Hypertension
- Trial name
- mHEART (NCT06523569)
- Testing
- Digital Blood Pressure Monitoring System, Mobile health application
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Pulmonary Edema
Predictors of Pulmonary Edema in Severe Preeclampsia
Pre-eclampsia is a multisystem major cardiovascular disease of pregnancy with hypertension its main clinical manifestation. Acute pulmonary edema, which signifies severe disease, is a leading cause of death in women with…
- Trial name
- NCT05095974
- Testing
- ultrasonography, echocardiography, thoracic electrical bioimpedence
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pre-Eclampsia
Hydroxychloroquine May be Beneficial for Preeclampsia
The purpose of this research is to investigate the impact of hydroxychloroquine on the incidence of hypertensive pregnancy disorders in women with a history of recurrent spontaneous abortion (RSA).
- Trial name
- NCT06020378
- Testing
- Hydroxychloroquine
- Where
- China
- Volunteers
- 462 people
- Sponsor
- RenJi Hospital
Hypertensive Disorder of Pregnancy, Preeclampsia
mHealth for Hypertensive Disorder of Pregnancy
Objectives: We have developed a cardiovascular disease management application named Heart4U, with the capability of integrating with the Electronic Medical Records (EMR) system within the hospital.
- Trial name
- NCT05995106
- Testing
- Heart4U
- Where
- South Korea
- Volunteers
- 580 people
- Sponsor
- Seoul National University Hospital
Leiden Factor V Deficiency,Preeclampsia, Doppler Examination
Prediction of Outcome in Severe Preeclampsia
this summary studied the predictive values of factor V Leiden mutation , doppler indices , placental pathology to unfavorable fetal and maternal outcomes
- Conditions
- Leiden Factor V Deficiency,Preeclampsia, Doppler Examination, Palental Pathology
- Trial name
- NCT03871764
- Testing
- blood sample , doppler of uterine vessel and placenta
- Volunteers
- 100 people
- Sponsor
- Cairo University
Preeclampsia Possible
Aspirin Dosing in Pregnancy
The purpose of this study is assess platelet phenotypes based on aspirin dosing in pregnant patients at risk for the development preeclampsia who are taking 81mg twice a day aspirin.
- Trial name
- NCT07525635
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Preeclampsia
Low Doses of Aspirin in the Prevention of Preeclampsia
Preeclampsia (PE) is a morbid and potentially lethal complication of pregnancy and is more common in women with specific risk factors.
- Trial name
- ASAPP (NCT04070573)
- Testing
- acetylsalicylic acid
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Weill Medical College of Cornell University
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Preeclampsia, Fetal Growth Restriction
First Trimester Prediction of Preeclampsia and Fetal Growth Restriction
To evaluate the feasibility of screening for preeclampsia and fetal growth restriction between 11-13+6 weeks' gestation utilizing the combination of uterine artery doppler, maternal blood pressure, maternal characteristics…
- Trial name
- NCT02379494
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Fetal Medicine Foundation
Pre-Eclampsia
Diagnostic Value of MicroRNA 210 In Preeclampsia
Pre-eclampsia is a disorder of pregnancy characterized by hypertension (defined as systolic blood pressure 140mmHg or diastolic blood pressure ⩾90 mmHg) and proteinuria (300 mg or greater in a 24 h urine specimen and/or protein…
- Trial name
- NCT03193554
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pre-Eclampsia
Preeclampsia Associated Vascular Aging
To evaluate cardiovascular health, especially endothelial health, of women after pre-eclampsia compared to women without pre-eclampsia, and to compare women who had taken PETN during pregnancy with women who had not attempted…
- Trial name
- PAVA (NCT04484766)
- Testing
- Primary data collection
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Jena University Hospital
Preeclampsia, Postpartum Period
The PreEclampsia Postpartum Prevention Trial
The goal of this clinical trial is to learn if a postpartum bundle intervention can improve cardiometabolic health and lifestyle-related factors in women who have had preeclampsia during their first pregnancy.
- Conditions
- Preeclampsia, Postpartum Period, Hypertension, Cardiovascular Diseases
- Trial name
- PEPP (NCT07199283)
- Testing
- Bundle Intervention
- Where
- 2 sites in Sweden
- Volunteers
- 356 people
- Sponsor
- Karolinska Institutet
Eclampsia Preeclampsia
Improved Characterisation of Eclampsia
Eclampsia is a serious pregnancy complication.In our study we aim to characterize the clinical signs and symptoms that occur prior to the onset of eclampsia in a prospectively collected cohort.And Compare these characteristics to…
- Trial name
- NCT05199558
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pre-Eclampsia, Volume Overload
PREDICTION OF FLUID RESPONSIVENESS WITH PASSIVE LEG RISING IN PREGNANT PATIENTS WITH SEVERE PREECLAMPSIA
BACKGROUND: A cornerstone of treatment in preeclampsia is to correct the potential hypovolemia with intravascular optimisation, which is usually performed as a fluid challenge.
- Conditions
- Pre-Eclampsia, Volume Overload, Hemodynamic Instability
- Trial name
- NCT03755843
- Testing
- PASSIVE LEG RISING
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- RAUL CARRILLO ESPER