Clinical trials: Pre- Frail
Frailty
Blood Flow Restriction Training in Pre-frail and Frail Older Adults
Frailty is most often defined as a syndrome of physiological decline in late life, characterized by marked vulnerability to adverse health outcomes.
- Trial name
- NCT04507152
- Testing
- Blood flow restriction resistance training, Resistance training
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- National Cheng Kung University
Frailty, Pre-operative Exercise
Home-based Exercise for Frail Individuals Prior to Cardiac Surgery
The goal of this quasi-experimental feasibility study is to determine if a home based exercise program, that is supported virtually by a physiotherapist, is feasible for frail adults that are waiting for cardiac surgery.
- Conditions
- Frailty, Pre-operative Exercise, Prehabilitation, Cardiac Surgery
- Trial name
- NCT05834556
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. Todd A Duhamel
Pre-Frail or Frail State
Randomized Controlled Trial of Community-based Nutritional, Physical and Cognitive Training Intervention Programmes for At Risk Frail Elderly
The aims of this proposed community-based randomized controlled trial are to evaluate the effectiveness of nutritional, physical exercise and cognitive training interventions for at-risk and frail elderly, to elucidate the…
- Trial name
- FIT (NCT00973258)
- Testing
- Nutritional Intervention, Physical Exercise, Cognitive Training
- Where
- Singapore
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- National Medical Research Council (NMRC), Singapore
Cancer, Frailty
Qigong for Pre-frail and Frail Older Cancer Survivors
To-date, there is no evidence on qigong's effects for improving well-being of pre-frail and frail older cancer survivors. Our aim is to conduct a pilot study for testing out the feasibility and acceptability of a qigong…
- Trial name
- NCT04694066
- Testing
- Qigong, Light flexibility exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 28 people
- Sponsor
- The University of Hong Kong
Geriatric Assessment, Health Services for the Aged
Geriatric-CO-mAnagement for Cardiology Patients in the Hospital
The primary objective of the evaluation study is to determine if geriatric co-management is superior to standard of care in preventing functional decline in older patients admitted for acute heart disease or Transcatheter Aortic…
- Conditions
- Geriatric Assessment, Health Services for the Aged, Cardiovascular Diseases, Activities of Daily Living
- Trial name
- G-COACH (NCT02890927)
- Testing
- Cardio-geriatric co-management
- Where
- Belgium
- Volunteers
- 454 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Frail Elderly
Effects of Remote Exercise on Physical Function in Pre-Frail Older Adults
This study aims to compare the effects of remote versus in-person exercise interventions on physical function, balance, gait stability, and fall efficacy in pre-frail older adults aged 65 years and above.
- Trial name
- NCT06672640
- Testing
- Remote Exercise Program, In-Person Exercise Program, Physical Activity Education
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kyungdong University
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Pre-frail
Effects of Whole Body Vibration in Pre-frail Individuals Over 65 Years of Age
In this study, individuals aged 65 and over who applied to the physical medicine and rehabilitation outpatient clinic with any complaint will be evaluated in terms of geriatric syndromes.
- Trial name
- NCT06004999
- Testing
- Whole body vibration, The exercise program on flat ground without a vibration platform
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Trakya University
Frail Elderly Syndrome
Protein Intake and Resistance Training in Aging
Resistance training combined with protein or amino acids supplementation has been shown to be promising for mitigating age-related disabilities and comorbidities.
- Trial name
- NCT01890382
- Testing
- Whey protein, whey plus creatine, leucine supplementation
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Frail Older Adult Syndrome, Nutrition Poor
PROTein to Enhance outComes of (Pre)Frail paTients Undergoing Cardiac Surgery
Heart disease in an aging population has resulted in heart surgery being offered to older and more frail patients. Frail patients which make up more than 50% of patients currently undergoing heart surgery are vulnerable to having…
- Conditions
- Frail Older Adult Syndrome, Nutrition Poor, Cardiovascular Morbidity
- Trial name
- PROTECT-CS (NCT04038294)
- Testing
- ISOlution protein supplement
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- St. Boniface Hospital
Fatigue
Evaluation and Training of Muscle Fitness in Pre-frail Individuals
Muscle strength and endurance are important indexes of fitness. The muscle strength is the most important single predict factor of functional ability in aged frail individuals.
- Trial name
- NCT02122653
- Testing
- Weight training, Electronic muscle stimulator
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Pre-frail Elderly
Effects of Metformin in Pre-frail Elderly
The purpose of this study is to investigate the effects of metformin to prevent frailty in pre-frail non-diabetic elderly. Several outcomes measured in this study are frailty status, quality of life, handgrip strength, gait…
- Trial name
- NCT02325245
- Testing
- Metformin
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Indonesia
Community-dwelling Seniors, History of a Fall in the Previous 12 Months
Zurich Disability Prevention Trial
This project was designed to optimizing vitamin D status in prefrail seniors age 70+ living at home and prevent their functional decline. We test 3 arms of monthly vitamin D supplementation.
- Trial name
- ZDPT (NCT01017354)
- Testing
- Hidroferol® (ES), ViDe3 (CH)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Zurich
Delirium in Old Age
Non-pharmacological Measures for the Prevention of Delirium in Frail Hospitalized Adults. Nursing Care (PREDELENF)
Background: Delirium is one of the most frequent, relevant, and increasing geriatric syndromes in hospitalized older adults. It is an indicator of poor prognosis, and its incidence increases with aging.
- Trial name
- PREDELENF (NCT07119385)
- Testing
- Multicomponent non-pharmacological interventions, Usual care
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Germans Trias i Pujol Hospital
Protein Metabolism
Peanut Sip Feeding Protocol
Peanuts are considered a functional food and regular consumption is associated with positive health effects. Protein is the second most common nutrient in peanuts after fat.
- Trial name
- NCT06693544
- Testing
- Peanut protein
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Health Services for the Aged, Geriatrics
Educational Guidelines Aimed at Pre-frail Elderly: Intervention Proposal
INTRODUCTION: aging is the natural process of deterioration of the reserves of biological systems, human beings are inherent to this process.
- Trial name
- NCT04997746
- Testing
- Multiprofessional educational interventions, Measurement of anthropometric measurements
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Leonardo Paroche de Matos
Pre-Frailty, Sarcopenia
TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status
The purpose of this study is to compare the effects of a standardized Traditional Chinese Medicine (TCM) formula versus beta-hydroxy-beta-methylbutyrate (HMB) on muscle strength and bone health in pre-frail older adults .
- Conditions
- Pre-Frailty, Sarcopenia, Muscle Atrophy or Weakness, Osteoporosis
- Trial name
- TCM-HMB-PF (NCT07597850)
- Testing
- TCM Formula, HMB (beta-Hydroxy-beta-methylbutyrate)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Frail Elderly Syndrome
A Health Promotion Program to Prevent Frailty and Improve Frailty Status Among Pre-frail Elderly: Frailty Intervention Through Nutrition Education and Exercises.
Prevention of frailty is a major concern in geriatrics due to its high prevalence and various adverse health outcomes among elderly population.
- Trial name
- FINE (NCT04327544)
- Testing
- Frailty Intervention
- Where
- Malaysia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Physical Frailty
Protein and Exercise to Counteract Frailty in Older Adults
The purpose of this study is to determine the effects of interventions with high-protein diet alone or in combination with resistance training on muscle mechanical function (muscle power and strength), frailty status, functional…
- Trial name
- NCT03842579
- Testing
- Resistance training, High-protein diet, Recommendations
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark