Clinical trials: PrEP Uptake
Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome
Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men
This is a randomized controlled trial to test a combination behavioral and biomedical interventions to improve the HIV prevention and care cascades in a population of mobile men in a high priority setting (fishermen in Kenya).
- Conditions
- Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome, HIV Infections, Sexually Transmitted Diseases, Viral
- Trial name
- NCT04772469
- Testing
- Provision of multiple self-tests, Small monetary incentives, Use of SMS/text reminders to motivate adherence to ART or PrEP
- Where
- Kenya
- Volunteers
- 934 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus
Mobile-health (mHealth) Intervention to Support HIV Self-testing and PrEP Uptake Among Young Men Who Have Sex With Men
The proposed study will involve adolescent (17-24 years old) men who have sex with men (described as YMSM hereafter) who meet eligibility criteria to participate.
- Trial name
- NCT04865341
- Testing
- IMB, Information-Only Control
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
PrEP Uptake, HIV
Implementation of PrEP Care Among Women in Family Planning Clinics
This study will evaluate implementation strategies to address barriers and increase uptake of PrEP among Black cisgender women in Planned Parenthood of Illinois (PPIL) health centers.
- Conditions
- PrEP Uptake, HIV, Prevention
- Trial name
- NCT06335121
- Testing
- POWER Up strategies -
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Improving Perceptions of HIV Risk, Improving Uptake of Pre-exposure Prophylaxis for HIV
Manicaland PrEP Uptake Through Interactive Counselling Trial
Primary Objective: The purpose of this trial is to evaluate the impact of an interactive tablet based counselling session correcting risk perception and addressing ambiguity around availability, usability and effectiveness of…
- Trial name
- NCT03565575
- Testing
- Interactive tablet-based quiz
- Where
- 8 sites in Zimbabwe
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- Simon Gregson
HIV Infections
A Peer-Driven Intervention to Increase PrEP Uptake Among Minority MSM
The objective of this study is to develop an effective peer-driven intervention (PDI) approach and assess its feasibility and efficacy on pre-exposure prophylaxis (PrEP) uptake among men who have sex with men.
- Trial name
- NCT05161663
- Testing
- Peer-driven intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT03652623
- Testing
- TDF/FTC
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
HIV/AIDS
Improving Uptake and Adherence to HIV Prevention Services With Pre-exposure Prophylaxis (PrEP), HIV Self- Testing and Adherence Support for Very High Risk HIV-negative Young Women Aged 15-24 in Kampala, Uganda
The main aim is to develop and assess an intervention to enhance initiation and adherence to PrEP among HIV negative young women of high risk (YWHR).
- Trial name
- POPPi (NCT04030520)
- Testing
- POPPi, Comparison
- Where
- Uganda
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Testing, PrEP Uptake
P3 Trial: Estimating the Impact of a Multilevel, Multicomponent Intervention to Increase Uptake of HIV Testing and Biomedical HIV Prevention
The major goal of this study is to evaluate a multi-component, multilevel HIV prevention intervention that targets theoretically-informed and empirically-identified barriers to and facilitators of both HIV testing and PEP/PrEP…
- Trial name
- P3 (NCT06785376)
- Testing
- DIY (Do It Yourself), TRUST, SOC
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Columbia University
Gender-Based Violence
Tu'Washindi na PrEP: Adolescent Girls in Kenya Taking Control of Their Health
This study is nested within the ongoing DREAMS (Determined, Resilient, Empowered, AIDS-free, and Safe) initiative in Siaya County, Kenya.
- Trial name
- NCT03938818
- Testing
- Tu'Washindi intervention, Control
- Where
- Kenya
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- RTI International
HIV Negative and Not Yet on PrEP
PrEP Talk: PrEP Uptake With Young Black MSM and Their Close Friends
Young Black MSM (YBMSM) are at critically high and disproportionate HIV risk. Reducing HIV incidence rates among YBMSM will likely require increased adoption of additional strategies such as pre-exposure prophylaxis (PrEP).
- Trial name
- PrEP-Talk (NCT04601649)
- Testing
- PrEP Talk
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- California State University, Dominguez Hills
HIV
Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study
To assess the acceptance rate, adherence, acceptability, and continuation of oral pre-exposure prophylaxis (PrEP) among young southern African women.
- Trial name
- NCT02732730
- Testing
- Truvada, Drug level counseling at Weeks 8 and 13
- Where
- 3 sites in South Africa, Zimbabwe
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT04077138
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
HIV Prevention, PrEP
Using PrEP, Doing It for Ourselves
The goal of this clinical trial is to test a new online program called UPDOs Protective Styles to help people in the southeastern United States learn about and start using PrEP (pre-exposure prophylaxis), a medicine that helps…
- Trial name
- UPDOs (NCT06638892)
- Testing
- Using PrEP, Doing it for Ourselves (UPDOs), Standard of Care
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Pre-Exposure Prophylaxis
HIV Pre-Exposure Prophylaxis Among an Unrecognized Sexual Minority Population
The Alternative Sexualities Health Research Alliance (TASHRA) will work collaboratively with Gilead Sciences, Inc. to study Pre-Exposure Prophylaxis (PrEP) uptake and adherence; levels of stigma around PrEP use; and changes in…
- Trial name
- PrEP4Kink (NCT05815030)
- Testing
- video informational/educational intervention
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- The Alternative Sexualities Health Research Alliance
Intervention, Control Condition
Adapting An Evidence-Based Intervention To Improve HIV Testing And PrEP Uptake In Vietnam
Young men who have sex with men are experiencing an ongoing HIV epidemic in Vietnam, with an HIV prevalence of 12%. However, HIV testing and pre-exposure prophylaxis (PrEP) use among young men who have sex with men remain low.
- Trial name
- NCT07113626
- Testing
- Mobile app
- Where
- Vietnam
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
HIV, Pre-exposure Prophylaxis
The Development of a Mobile-based App to Increase Uptake of Pre-Exposure Prophylaxis (PrEP) by Men Who Have Sex With Men in China
This study aims to use a mini-application on the popular Chinese social media mobile platform, WeChat, to improve HIV pre-exposure prophylaxis (PrEP) uptake among at-risk men who have sex with men (MSM).
- Trial name
- NCT04426656
- Testing
- Phone application
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
PrEP Uptake
PrEP US NoW: PrEP Utilization Through Increasing Social Capital Among YBMSM Networks With Women
This project is a randomized intervention looking at PrEP uptake among young, black men who identify as gay, bisexual, or same gender loving, utilizing black females within the community to help deliver study related topics.
- Trial name
- NCT07024745
- Testing
- Intervention Group, Control (Standard treatment)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hiv
Increasing PrEP With Trans Women in the Deep South
The goal of this to address barriers and facilitators to PrEP uptake, and encourage adherence among trans women via a single arm stepped wedge clinical trial.
- Trial name
- T'Cher (NCT05689281)
- Testing
- Peer PrEP Navigation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CrescentCare
Risk Factor
Motivational Interviewing to Increase PrEP Uptake (MI-PrEP)
The purpose of this study is to test a counseling program for Black women at high risk for HIV
- Trial name
- MI-PrEP (NCT03592719)
- Testing
- Experimental Intervention (MI-PrEP), Enhanced Treatment as Usual (E-TAU)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV Prevention
Telehealth as a Modality to Increase the Uptake of PrEP Services in Black and Latino: "e-PrEP"
To evaluate if utilizing Telehealth medicine for access to HIV PrEP will engage more Black and Latino Men who have sex with Men (MSM)
- Trial name
- e-PrEP (NCT05528653)
- Testing
- Descovy
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vivent Health