Clinical trials: Posttraumatic Stress Symptoms
Posttraumatic Stress Disorder
Testing the Efficacy of an Eye-tracking-based Treatment in Reducing Stress-related Symptoms in Veterans With PTSD
The study will examine the efficacy of a feedback-based treatment applying eye-tracking (Gaze-Contingent Music Reward Therapy) to change attention and gaze patterns associated with angry faces relative to a response-time-based…
- Trial name
- NCT05243459
- Testing
- Gaze-Contingent Feedback Training, Attention Bias Modification, Non-Contingent Feedback Training
- Where
- Israel
- Volunteers
- 121 people
- Sponsor
- Tel Aviv University
PostTraumatic Stress Disorder, Eating Disorder
Integrated Treatment for Co-occurring Eating Disorders and Posttraumatic Stress Disorder
Although psychotherapy for eating disorders (EDs) can be effective, approximately 50% of those who complete a course of the best available therapy continue to have significant ED symptoms at the end of treatment.
- Trial name
- NCT03502564
- Testing
- CBT for ED, Concurrent CBT for ED and PTSD
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University Health Network, Toronto
Posttraumatic Stress Disorder
Attentional Bias Modification in Patients With Posttraumatic Stress Disorder
Randomized, placebo-controlled trial of 9 sessions of computerized attentional bias training on attentional bias and on symptoms of Posttraumatic Stress Disorder.
- Trial name
- NCT00764101
- Testing
- Attentional Bias Modification
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- PsyQ
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Stress Disorders
Effects of an Alternative Treatment for Military Sexual Trauma on PTSD Symptoms, Neurosteroids and Brain Function
Our specific aims are: 1. To examine the efficacy of GIFT in improving MST-related clinical outcomes in women veterans 2. To examine the effects of GIFT on fronto-limbic brain function and 3.
- Trial name
- NCT00374738
- Testing
- Guided Imagery for Trauma (GIFT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Samueli Institute for Information Biology
Violence, Depression
A Pilot Evaluation of the Pregnant Moms' Empowerment Program
This project will use a longitudinal design with assessments at baseline (T1), post-treatment (T2), 3 month post-partum (T3), 1 year postpartum (T4) and 3.5-5 years postpartum to examine whether the PMEP improves participants'…
- Conditions
- Violence, Depression, Posttraumatic Stress Disorder, Parenting
- Trial name
- NCT05011825
- Testing
- Pregnant Moms' Empowerment Program
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Anxiety, Depression
Implementation of Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: Pilot
To implement Problem Management Plus (PM+) in Syrian refugees with this pilot study in Turkey with the aim of informing the definitive RCT about drop-out rates and estimated effect sizes.
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- STRENGTHS (NCT03567083)
- Testing
- Problem Management Plus (PM+)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul Sehir University
Posttraumatic Stress Disorder
Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault
Interventions are available to all adult women sexual assault survivors to reduce the risk of pregnancy and sexually transmitted infection, yet no interventions are provided to reduce posttraumatic stress.
- Trial name
- NCT04334356
- Testing
- Mobile Web App
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Grief
Iwankapiya-Healing: Historical Trauma Practice and Group IPT for American Indians
This study will pilot an intervention that combines group Interpersonal Psychotherapy (IPT), an empirically-supported treatment, and the Historical Trauma and Unresolved Grief Intervention (HTUG), a Tribal Best Practice for…
- Conditions
- Depression, Grief, PTSD, Interpersonal Relations
- Trial name
- HTUG-IPT (NCT02124694)
- Testing
- HTUG
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
Posttraumatic Stress Disorder (PTSD), Anxiety
Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women
Trauma exposure, posttraumatic stress disorder (PTSD), and substance use disorder (SUD) present major threats to public health. PTSD and SUD are major correlates of disability, often resulting in severe social and occupational…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Anxiety, Depression - Major Depressive Disorder
- Trial name
- MSC for PTSD (NCT06646692)
- Testing
- Mindful Self Compassion, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of California, Los Angeles
Stress Disorder, Posttraumatic, Stress, Psychological
Neurological and Psychological Effects of Combat-Related Stress
The purpose of this study is to determine what is the neurological and cognitive impact of combat exposure and prolonged stress, in the form of service in the Israeli Defense Forces.
- Trial name
- NCT04651192
- Testing
- Combat Exposure
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel Aviv University
Sleep Disorders, PTSD
Efficacy of a Brief Nightmare Treatment for Veterans
The purpose of this study is to find out what effects Exposure, Rescripting, and Relaxation Therapy (ERRT) has on nightmares and associated problems in veterans.
- Conditions
- Sleep Disorders, PTSD, Suicide
- Trial name
- NCT01220401
- Testing
- exposure, relaxation, and rescription therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Tulsa
TBI (Traumatic Brain Injury)
Evaluation of Military Service and Family Members for Post Concussive and Posttraumatic Stress Symptoms
This protocol is designed to facilitate the recruitment, screening and registry of Military Service Members (SMs) and individuals eligible for care in the Department of Defense (DoD) healthcare system.
- Trial name
- MRP (NCT03191357)
- Testing
- n/a observational
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Posttraumatic Stress Disorder
Bright Light: An Adjunct Treatment for Combat Posttraumatic Stress Disorder (PTSD)
The investigators are testing novel treatments for combat PTSD: bright light exposure and negation ion exposure.
- Trial name
- NCT00701064
- Testing
- Bright Light Exposure, Negative Ion Generator
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- VA Office of Research and Development
Depression, Posttraumatic Stress Disorder
Randomized Controlled Trial of Interpersonal Psychotherapy for Depression and PTSD Among HIV+ Women in Kenya
The aim of this study is to conduct a 12-week IPT+TAU versus wait list TAU in a cohort of HIV+GBV+ women in Nyanza Province to relieve depression and PTSD and improve ARV adherence.
- Conditions
- Depression, Posttraumatic Stress Disorder, HIV
- Trial name
- NCT02320799
- Testing
- interpersonal psychotherapy, treatment as usual
- Where
- Kenya
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder
Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD
This study is a longitudinal, multicenter, single-blind, two-arm randomized controlled trial designed to evaluate the effectiveness of Multi-Modal Cognitive Processing Therapy (MMCPT) for individuals with posttraumatic stress…
- Trial name
- PTSD (NCT07105345)
- Testing
- Cognitive Processing Therapy (CPT), Treatment as Usual (TAU)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Posttraumatic Stress Disorder (PTSD), Insomnia
Yoga Nidra for Insomnia and Posttraumatic Stress Symptoms
This randomized feasibility study is designed to investigate the feasibility of recruitment and delivery of two variations (brief; full) of a virtual Integrative Restoration (iRest) yoga nidra meditation intervention in stressor…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Insomnia, Stressor, Psychological, Psychological Trauma
- Trial name
- NCT06888336
- Testing
- Yoga nidra (full), Yoga nidra (brief)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University College, London
Fibromyalgia (FM), Posttraumatic Stress Disorder (PTSD)
Treatment of Fibromyalgia and PTSD With Live and Inactive Vagus Nerve Stimulation With PEPC
Fibromyalgia (FM) pain and PTSD are highly prevalent and comorbid with associated increased risk of negative physical and mental health outcomes, including higher risk for opioid use and suicide.
- Trial name
- SWIFT-RELIEVE (NCT07718984)
- Testing
- tAN plus PEPC
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder (PTSD), Depression
Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial
The overall objective of this study is to test the effectiveness of a systems-level approach to primary care recognition and management of PTSD and depression in the military health system.
- Trial name
- STEPS UP (NCT01492348)
- Testing
- STEPS UP, OUC
- Where
- 6 sites in United States
- Volunteers
- 666 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill