Clinical trials: Postsurgical Pain
Intensive Care Unit, Cardiac Surgery
The Effect of Light Therapy on Post-Surgical Pain
Researchers aim to demonstrate that the use of phototherapy is feasible and may reduce acute postoperative pain based on recent literature.
- Trial name
- NCT05853731
- Testing
- Green light emitting diode, White light emitting diode
- Where
- United States
- Sponsor
- Mayo Clinic
Preemptive Analgesia, Sex Difference
Sex Difference in Preemptive Analgesic Effects With Flurbiprofen Axetil on Postoperative Pain and Sleep Quality
In humans and animals, circadian rhythm sleep cycle plays an important role on maintaining and regulating basic physiological homeostasis, such as cognitive function, glucose metabolism, memory consolidation, immune function and…
- Conditions
- Preemptive Analgesia, Sex Difference, Flurbiprofen Axetil, Postoperative Pain
- Trial name
- NCT04627779
- Testing
- preemptive analgesia with flurbiprofen axetil
- Volunteers
- 100 people
- Sponsor
- Beijing Friendship Hospital
Postoperative Pain, Pediatric Anesthesia Department
Pediatric Postoperative Pain Management
This prospective, observational study evaluates the effectiveness of perioperative pain management strategies in pediatric patients undergoing elective surgical procedures.
- Conditions
- Postoperative Pain, Pediatric Anesthesia Department, Regional Anaesthesia, Pain Scale
- Trial name
- NCT07392827
- Where
- Turkey (Türkiye)
- Volunteers
- 219 people
- Sponsor
- Hacettepe University
Laparoscopic Cholecystectomy, Postoperative Pain
Local Infiltration With Levobupivacaine During Laparoscopic Cholecystectomy
Randomized controlled trial on laparoscopic cholecystectomy. Interventional group: preincisional infiltration with levobupivacaine. Control group: no local infiltration.
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Local Infiltration, Levobupivacaine
- Trial name
- NCT04697329
- Testing
- Preincisional infiltration with levobupivacaine
- Where
- Spain
- Volunteers
- 233 people
- Sponsor
- Hospital Universitario de Móstoles
Pain, Postoperative
Comparison of The Continous Suprainguinal Fascia Iliaca Compartment Block and Continous Epidural
This study evaluates the effectiveness of postoperative analgesia quality, Interleukin-6, Hemodynamic stability and QoR-40 of continuous Suprainguinal Fascia Iliaca Compartment Block (S-FICB) compared with continuous epidural in…
- Trial name
- NCT06636331
- Testing
- Continuous Suprainguinal Fascia Iliaca Compartment Block, Continuous Epidural
- Where
- 2 sites in Indonesia
- Volunteers
- 46 people
- Sponsor
- Udayana University
Obesity, Postoperative Pain
Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy
Opioid free anesthesia is an anesthetic technique, in which administration of multimodal analgesia and sympathicolytics provides hemodynamic stability without use of opioids.
- Conditions
- Obesity, Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT04260659
- Testing
- Dexmedetomidine Hydrochloride [Dexdor], Remifentanil [Ultiva], Ketamine [Ketalar]
- Where
- Poland
- Volunteers
- 59 people
- Sponsor
- Medical University of Warsaw
Caffeine, Pain, Joint
Pain Management After Shoulder Arthroplasty
Pain control is a critical after many surgical procedures. It is well known that orthopaedic surgeries are among the most painful procedures, with total joint arthroplasty being a clear example of this situation.
- Trial name
- NCT04872270
- Testing
- Total Shoulder Arthroplasty, Caffeine Pill, Percocet 10Mg-325Mg Tablet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Pain, Acute, Hip Arthropathy
Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty
Multimodal pain management is essential for recovery after surgery, aiming to target different pain mechanisms to minimize opioid usage and opioid-related adverse effects.
- Conditions
- Pain, Acute, Hip Arthropathy, Analgesia, Postoperative Pain
- Trial name
- RECIPE (NCT04123873)
- Testing
- Paracetamol, Ibuprofen, Dexamethasone
- Where
- 7 sites in Denmark
- Volunteers
- 1,060 people
- Sponsor
- Naestved Hospital
Postoperative Pain
Pain Control After Orthognathic Surgery
This study will assess the efficacy and safety of levobupivacaine for postoperative pain control in patients received orthognathic surgery.
- Trial name
- PCOGS (NCT01418183)
- Testing
- Trigeminal nerve block
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Pain, Postoperative
Oxycodone vs. Fentanyl in Early Postoperative Pain After Total Hip Replacement
Oxycodone is one of the most widely used opioids for pain treatment. Many studies demonstrated good efficacy of oxycodone on postoperative pain.
- Trial name
- NCT03019562
- Testing
- Oxycodone, Fentanyl
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Kyunghee University Medical Center
Pain, Postoperative
Ultrasound Guided Quadratus Lumborum Block for Post Operative Analgesia After Hip Arthroplasty
The study evaluates the effectiveness of anterior quadratus lumborum block for post operative analgesia after hip arthroplasty. Half of the participants will receive ultrasound guided anterior quadratus lumborum block using 30ml…
- Trial name
- NCT03502369
- Testing
- Anterior Quadratus lamborum block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Symptomatic Irreversible Pulpitis
Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic
This study evaluates postoperative pain and treatment outcomes following vital pulp therapy and root canal treatment in patients with symptomatic teeth.
- Trial name
- NCT07549620
- Testing
- Vital Pulp Therapy, Root Canal Treatment
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Ain Shams University
Microbial Substitution, Tryptophan Metabolism Alterations
Impact of Gut Microbiota and Tryptophan Metabolites on Acute Pain in Lumbar Disc Herniation Surgery Patients
It is well-established that the gut microbiota plays a crucial role in various pain mechanisms, including visceral pain, inflammatory pain, headache, neuropathic pain, and opioid tolerance.
- Conditions
- Microbial Substitution, Tryptophan Metabolism Alterations, Postoperative Pain, Acute
- Trial name
- NCT06502223
- Testing
- Pain Perception in Patients Undergoing Lumbar Disc Herniation Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Dokuz Eylul University
Postoperative Pain, Opioid Use
Erector Spinea Plane Block in Pediatric Hip Surgery
This prospective randomized controlled double-blind study will be carried out to evaluate the effect of ultrasound-guided erector spinae plane block on the postoperative analgesia in children after hip surgeries, the total…
- Trial name
- NCT04374396
- Testing
- Real ultrasound-guided single shot erector spinae plane block (ESP B)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Preoperative Analgesia in Non-gynecological Cancerous Women Who Underwent Elective Total Abdominal Hysterectomy
Comparison of effectiveness of preoperative Gabapentin with Celecoxib in reducing acute postoperative pain in abdominal hysterectomy, A randomized double blind controlled trial
- Trial name
- NCT03672162
- Testing
- Total abdominal hysterectomy
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pain, Postoperative
The Effect of Parecoxib Sodium Intravenous Patient-controlled Analgesia in Laparotomic Liver Resection
The investigators hypothesized that using new intravenous infusion pump of patient-controlled analgesia (parecoxib sodium 1 mg/mL + normal saline) would significantly improve postoperative pain control compare to conventional…
- Trial name
- NCT02408146
- Testing
- conventional intravenous infusion pump, parecoxib, intravenous infusion pump of patient-controlled analgesia
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Pain, Postoperative
PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial
Trial name: PAracetamol and NSAID in combination: A randomised, blinded, parallel, 4-group clinical trial Trial acronym: PANSAID Background: Effective postoperative pain management is essential for the well-being and…
- Trial name
- PANSAID (NCT02571361)
- Testing
- Paracetamol (1g x 4), Ibuprofen (400 mg x 4), Paracetamol (0,5 g x 4)
- Where
- 6 sites in Denmark
- Volunteers
- 556 people
- Sponsor
- Daniel Hägi-Pedersen
Neuromuscular Blockade
Deep Neuromuscular Blockade on Postoperative Pain
This study aims to investigate the impact of varying degrees of neuromuscular blockade on postoperative pain in pediatric patients aged over 2 months to under 7 years undergoing laparoscopic surgery under general anesthesia.
- Trial name
- NCT06679569
- Testing
- rocuronium 0.2 mg/kg/hr continuous infusion, rocuronium 0.6 mg/kg/hr continuous infusion
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Seoul National University Hospital
Phantom Limb Pain After Amputation
Preventing Chronification of Phantom Limb Pain Through Mirror Therapy in Conjunction With tDCS
Background: Most amputees experience phantom limb pain (PLP), for years after amputation. Virtually all PLP research to date has focused on the mechanisms of chronic PLP, ignoring the mechanisms of chronification.
- Trial name
- NCT07139483
- Testing
- Trans Direct-Cranial Stimulation (tDCS), Mirror therapy
- Where
- 3 sites in Israel
- Volunteers
- 108 people
- Sponsor
- University of Haifa
Extremity Injury
Upper Extremity Post-op Splints: Do They Improve Post-operative Pain?
The goal of this study is to determine if applying a rigid splint helps to reduce pain following operative fixation of upper extremity fractures.
- Trial name
- NCT03891966
- Testing
- Rigid Splint, Soft Dressing
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- NYU Langone Health