Clinical trials: Postprandial Hyperglycemia
Type 1 Diabetes, Diabetes Complications
Individualised Postprandial Glucose Responses in Type 1 Diabetes
Type 1 diabetes (T1D) is a lifelong disease which stops the body from producing insulin - an important hormone that controls blood sugar (glucose) levels.
- Conditions
- Type 1 Diabetes, Diabetes Complications, Postprandial Hyperglycemia
- Trial name
- NCT05231642
- Testing
- Nutritional Interventional
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Sunderland
Parkinsonian Disorders
Post-prandial Hypotension and Sleepiness in Parkinson's Disease and Other Synucleinopathies
Excessive daytime sleepiness (EDS) is observed in 30 to 50 % of patients with Parkinson's disease (PD) patients, Dementia with Lewy Bodies (DLB) and Multiple System Atrophy (MSA).
- Trial name
- HYPOSOMNPARK (NCT02021903)
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Toulouse
Hyperglycemia, Glucose Metabolism Disorders
Effect of Lysine and Phosphorus Fortification on Glycemic Index and Postprandial Glycemia in Double Fortified Bread
The goal of this clinical trial is to investigate the effect of lysine and phosphorous on the glycemic index (GI) of white bread and postprandial glycemia.
- Conditions
- Hyperglycemia, Glucose Metabolism Disorders, Metabolic Disease, Glycemic Index
- Trial name
- LP-DFB-GI-PG (NCT05903625)
- Testing
- Control Group - Standard White Bread, Lysine Group - Lysine-Fortified Bread, Phosphorus Group - Phosphorus-Fortified Bread
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Intervention
Pre-meal Load of Raw Almonds and Postprandial Hyperglycemia
A few studies show the effect of almonds on postprandial hyperglycemia (PPHG); high blood glucose after meals. In our previous study on intervention with almonds, we observed a significant decrease in HbA1C and a small decrease…
- Trial name
- NCT04769726
- Testing
- almonds
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Obesity
Study About High Fat Meal and Postprandial Lipemia
The hypothesis of the proposed project is that after a fat overload, the postprandial response is different in both groups, suggesting that the LPP will present the most significant damage in endothelial vasomotion in obese…
- Trial name
- NCT01692327
- Testing
- High fat meal
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Impaired Glucose Tolerance
Postprandial Fatty Acid Metabolism in the Natural History of Type 2 Diabetes (T2D)
Lipotoxicity-causing fatty acid overexposure and accretion in lean tissues leads to insulin resistance and impaired pancreatic β-cell function - the hallmarks of T2D - contributing to associated complications such as heart…
- Trial name
- AGL11 (NCT02808182)
- Testing
- Nicotinic acid, [7,7,8,8-2H]-palmitate, [U-13C]-palmitate
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Glucose Intolerance, Diabetes Mellitus, Type 2
Effects of Seaweed Extract on Blood Glucose Response to Sucrose
This study will examine the impact of the seaweed (Ascophyllum nodosum) extract on blood glucose levels after a sugary drink in healthy subjects.
- Conditions
- Glucose Intolerance, Diabetes Mellitus, Type 2, Healthy Diet, Postprandial Hyperglycemia
- Trial name
- NCT05461560
- Testing
- Sucrose solution, Seaweed extract in sucrose solution
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Type 1 Diabetes, Hyperglycemia, Postprandial
Effect of Postprandial Hyperglycemia on Vasculature in Type 1 Diabetes and Healthy Adults
To the investigator's knowledge, there are no data available in the current literature regarding the acute effects of postprandial hyperglycemia and insulin timing on myocardial perfusion in people with type 1 diabetes (T1D).
- Trial name
- WBH001 (NCT04730882)
- Testing
- Mixed Meal
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Hyperglycemia, Hyperglycemia, Postprandial
NUTRACORE, Glycaemic Index and Appetite
In recent decades, the world prevalence of obesity and type 2 diabetes (DMT2) has increased dramatically, resulting in a global epidemic.
- Conditions
- Hyperglycemia, Hyperglycemia, Postprandial, Appetitive Behavior, Hyperinsulinism
- Trial name
- NTRCR-vivo (NCT05528874)
- Testing
- Same intervention for both groups: glycaemic index assessment of 3 biscuits recipes, Crossover: Recipe 4 before recipe 5, Crossover: Recipe 5 before recipe 4
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Diabetes Mellitus, Adult-Onset, Platelet Dysfunction
Oleocanthal Rich Olive Oil Acute Effects on Hyperglycemia and Platelet Activation in T2DM
This is a pilot acute dietary intervention study with a randomized cross-over design aiming to investigate whether acute supplementation of extra virgin olive oil (EVOO) rich in oleocanthal could attenuate postprandial…
- Conditions
- Diabetes Mellitus, Adult-Onset, Platelet Dysfunction, Postprandial Hyperglycemia, Lipidemia
- Trial name
- NCT04419948
- Testing
- White bread, Butter, Refined olive oil
- Where
- Greece
- Volunteers
- 15 people
- Sponsor
- Harokopio University
Diabetes, Type 2
The Study to Investigate the Contribution of Basal and Postprandial Glucose to Overall Hyperglycemia in T2DM
There was no any China mainland data showing the contribution of BBG and PBG to HbA1c in T2DM patients treated with OADs using the CGM method.
- Trial name
- NCT02648685
- Where
- China
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- West China Hospital
PreDiabetes, Postprandial Hyperglycemia
Mealtime Walking Study to Improve Postprandial Metabolic Response
This randomized crossover trial will investigate the metabolic responses following the consumption of a bagel+juice meal under 3 conditions: control, fiber (positive control), and postmeal walk in15 healthy adults.
- Trial name
- NCT04499287
- Testing
- 15-minute walk at preferred walking speed., Fiber, control
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Beta-Thalassemia, Insulin Resistance
Resistance Exercise on Postprandial Hyperglycemia in Patients With B-thalassemia Exhibiting Resistance to Insulin
It is known that postprandial hyperglycemia increases the cardiometabolic risk in both diabetic and non-diabetic patients. Moreover, there is insufficient data on the effectiveness of exercise on preventing Type II diabetes…
- Conditions
- Beta-Thalassemia, Insulin Resistance, PreDiabetes, Diabetes Mellitus, Type 2
- Trial name
- NCT03889977
- Testing
- Resistance exercise
- Where
- Greece
- Volunteers
- 6 people
- Sponsor
- University of Thessaly
Hyperglycaemia
Effects of Polyphenols Found in Pomegranate Juice on Postprandial Blood Glucose in Vivo
Consumption of carbohydrate containing foods or sugary drinks brings about changes to the blood glucose levels. After a meal or drink, blood glucose rises until it reaches a peak concentration usually after 30 minutes.
- Trial name
- NCT02624609
- Testing
- Control without pomegranate juice, Test with pomegranate juice
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Type 1 Diabetes
Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia
This study aims to compare the post-meal blood glucose values of two drugs in a "real-world" setting.
- Trial name
- NCT01621776
- Testing
- Apidra, Humalog, Novolog
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Florida
Postprandial Hyperglycemia
Beneficial Effect of Xylose Consumption on Postprandial Hyperglycemia
The present study determined the effect of Xylose consumption on postprandial hyperglycemia in normal (n=25) and hyperglycemic subjects (n=50).
- Trial name
- NCT02654301
- Testing
- Test 1, Test 2, Test 3
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake 2 ( WE-MACNUTR 2)
Diet and nutrition are key to maintain human health. Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR) trial investigates individualized postprandial glycemic responses to different proportions of dietary fat and…
- Trial name
- NCT05161182
- Testing
- High fat, low carbohydrate diet, Low fat, high carbohydrate diet
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Westlake University
Healthy Diet, Postprandial Hyperglycemia
Effect of the Consumption of Alcohol-free Beers With Different Carbohydrates Composition on Postprandial Metabolic Response
The overall objective of this study is to explore the glycemic index and glycemic load induced by an alcohol-free beer with modified composition (including almost full fermentation of carbohydrates and the addition of…
- Trial name
- NCT04790877
- Testing
- Sub-study 1, Sub-study 2
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Postprandial Hyperglycemia, Lipidemia
Black Rice Anthocyanin in Mixed Meals: Influence on Postprandial Glycaemic and Lipid Responses Among Healthy Individuals
The diabetes epidemic is a pertinent concern globally. The prevalence of this metabolic disease among adults had been disclosed by the World health Organisation (WHO), reporting a total of 422 million diabetic adults and 3.7…
- Trial name
- NCT04063137
- Testing
- Anthocyanin fortified bread with beef patty (35% fat)
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Type1diabetes
Universal Fixed Meal Boluses Usage in Patients With Medtronic Minimed 780G Pumps
Cross-over study of 20 pediatric patients (age 7-19) randomized to the group receiving universal fixed meal boluses coefficients (300/TDD for breakfast and 400/TDD other meal) or to the group with individualized coefficients for…
- Trial name
- NCT06372392
- Testing
- Universal meal coefficient utilization
- Where
- Estonia
- Volunteers
- 20 people
- Sponsor
- Tartu University Hospital