Clinical trials: Postpartum Period
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
Maternal Vital Signs, Skin-to-skin Contact
The Effect of Skin-to-Skin Contact Applied in the Early Postpartum Period on Maternal Pain, Birth Satisfaction, and Maternal Vital Signs Dynamics
Skin-to-skin contact (STSC) initiated within the first hour after birth is a fundamental practice that supports both the mother's and the newborn's physiological and psychological adaptation (Çelik \& Kök, 2022).
- Conditions
- Maternal Vital Signs, Skin-to-skin Contact, Birth Satisfaction
- Trial name
- NCT07304037
- Testing
- A solid hour of skin-to-skin contact
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy Related, Vitamin B 12 Deficiency
Vitamin B12 Supplementation During Pregnancy on Cognitive Development
Scientific basis: Globally, vitamin B12 deficiency is one of the most common micronutrient deficiencies. The only relevant source of vitamin B12 is animal-source foods and poor gut function may decrease absorption.
- Conditions
- Pregnancy Related, Vitamin B 12 Deficiency, Anemia
- Trial name
- VitaPreg (NCT03071666)
- Testing
- cobalamin
- Where
- Nepal
- Volunteers
- 800 people
- Sponsor
- Centre For International Health
Well-Being, Psychological, Dissociation
An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers
The proposed study will collect novel data evaluating the feasibility of the NFB training program delivered in an outpatient mental health setting and its influence on mothers' overall sense of well-being, and further investigate…
- Conditions
- Well-Being, Psychological, Dissociation, Maternal Care Patterns, Maternal Behavior
- Trial name
- NCT06054412
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Mother-child Relationship Disturbances
Mother-Infant Psychoanalysis Project of Stockholm (MIPPS)- Follow-up at 4½ Years
An RCT comparing mother-infant psychoanalytic treatment (MIP) with Child Health Centre care in cases of mother-infant relationship disturbances was performed on 80 cases in Stockholm 2005-2008.
- Trial name
- MIPPS-02 (NCT01087112)
- Testing
- Mother-Infant Psychoanalytic tmt, Child Health Centre care
- Where
- Sweden
- Volunteers
- 71 people
- Sponsor
- Karolinska Institutet
Postpartum Hypertension (PPHT)
PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy
This randomized controlled trial compares two common medications, labetalol and extended-release nifedipine, to determine which is more effective at managing postpartum high blood pressure.
- Trial name
- PEACE (NCT06915792)
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Los Angeles
Post Partum Hemorrhage, Fibrinolysis; Hemorrhage
Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery
The investigators prepared a novel study of tranexamic acid (TXA) designed to estimate the quantity of blood loss in women undergoing elective repeat cesarean deliveries.
- Conditions
- Post Partum Hemorrhage, Fibrinolysis; Hemorrhage, Blood Loss
- Trial name
- TXA (NCT03856164)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Gestational Diabetes
Oral Glucose Tolerance Test and Post Partum Diagnosis of Diabetes Mellitus, Type 2 (DT2 Post-Partum)
Diabetes mellitus, type 2, is a chronic disease which can be linked with many complications in connexion with impaired blood glucose balance.
- Trial name
- NCT03644004
- Testing
- frequency of diabetes mellitus, type 2, diagnosis in patients with medical history of gestational diabetes.
- Where
- France
- Volunteers
- 173 people
- Sponsor
- Hospices Civils de Lyon
Bipolar Disorder
Pharmacokinetics of Quetiapine Across Pregnancy and Postpartum
The widespread and common use of quetiapine in childbearing and pregnant women demands more data to inform dosing and toxicity in pregnancy.
- Trial name
- Quetiapine (NCT02978534)
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Northwestern University
Preeclampsia Postpartum
Guideline-directed Management and Therapy (GDMT) for the Prevention of Postpartum Cardiac Dysfunction in Preeclamptic African American Women
This is a single-center, open-label pilot study looking at how Guideline-directed management and therapy (GDMP) in post-partum women with preeclampsia can improve Global Longitudinal Strain (GLS).
- Trial name
- GDMT For PE (NCT05534932)
- Testing
- Remote Patient Monitoring
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Postpartum Hemorrhage
Postpartum Oxytocin Administration in the Era of Delayed Cord Clamping
Increased blood loss after vaginal or cesarean delivery is one of the top causes of maternal complications. Oxytocin is a common medication given to mothers by IV or an injection to limit the amount of blood loss after delivery.
- Trial name
- PROCEEDING (NCT04632264)
- Testing
- Initiation of standard postpartum oxytocin immediately following fetal shoulder delivery, Initiation of standard postpartum oxytocin immediately following placenta delivery
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Columbia University
Postpartum Hemorrhage
Effects of Oxytocin and Carbetocin on Renal System in Cesarean Sections
The aim of this study is to evaluate the renal outcome of patients undergoing elective C/S where oxytocin or carbetocin is used for postpartum hemorrhage prophylaxis.
- Trial name
- NCT03939806
- Testing
- Oxytocin, Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ufuk University
Cesarean Section Complications, Postpartum Hemorrhage
The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery
This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT03967171
- Testing
- before uterine incision oxytocin, after clamping the umbilical cord oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Breast Feeding, Parenting
Doula Home Visiting Randomized Trial
The purpose of this randomized controlled trial is to examine whether evidence-based home visiting programs enhanced by doula services have effects on positive parenting practices, breastfeeding, and child and maternal health…
- Conditions
- Breast Feeding, Parenting, Child Development, Depression, Postpartum
- Trial name
- NCT01947244
- Testing
- Doula Home Visiting, Case management
- Volunteers
- 312 people
- Sponsor
- University of Chicago
Postpartum Pelvic Floor Function and Symptoms
Motherhood and Pelvic Health (MAP Study)
The Motherhood and Pelvic health study (MAP), Bridging physical and cultural determinants of postpartum pelvic floor support and symptoms following vaginal delivery, uses mixed methods research to study the influences of…
- Trial name
- NCT02512016
- Testing
- Study Procedures
- Where
- United States
- Volunteers
- 1,079 people
- Sponsor
- University of Utah
Postpartum Women
Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers
The goal of this study is to develop a postpartum depression (PND) Risk index using the UK Biobank dataset, and to validate the risk index in Hong Kong postpartum women.
- Trial name
- SLEEP-PD-HK (NCT07600593)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Postpartum Hemorrhage
Cervical Traction and Postpartum Hemorrhage
The purpose of the research conducted within the scope of the doctoral thesis study is to evaluate the effect of cervical traction applied at the end of the third stage of childbirth on the oxytocin level and postpartum bleeding…
- Trial name
- NCT06179147
- Testing
- cervical traction
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ege University
Postpartum Hemorrhage
Effectiveness of Tranexamic Acid When Used as an Adjunct to Misoprostol for the Treatment of Postpartum Hemorrhage
This study is a randomized, double-blind, placebo controlled trial that will enroll 250 women (125 per study arm). The objective of the study is to determine the efficacy and tolerability of oral tranexamic acid when used as an…
- Trial name
- NCT02805426
- Testing
- Tranexamic Acid, Misoprostol
- Where
- 4 sites in Senegal, Vietnam
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Depression
Prevalence of Postpartum Depression in Hospital Jose E. Gonzalez
This research will use the Edinburgh Scale Of Post partum depression to evaluate patients during their 4th to 6th after delivery, and the investigators will compare the results with those found in other countries with population…
- Trial name
- NCT01658098
- Testing
- edinburgh postpartum depression scale questionary
- Where
- Mexico
- Volunteers
- 348 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Postnatal Depression
A Problem-Solving Intervention for Women With Suicidal Ideation During Postnatal Period in Pakistan
The aim of this study is to determine the feasibility and acceptability of culturally adapted CMAP for suicidal Ideation for women in postnatal period. Objectives 1.
- Trial name
- NCT05852314
- Testing
- Culturally Adapted Manual Assisted Therapy (CMAP-SI)
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Pakistan Institute of Living and Learning