Clinical trials: Postoperative Vomiting
Prevention of Postoperative Ileus
Mouth Dissolving Mosapride Tables Enhance Post Cesarean Gut Recovery
Giving women one day before and immediately after cesarean section a mouthly dissolving mosapride tablets 2every every 8 hours for maximum of 5 days ,or getting recovered gastrointestinal functions And assess preoperative…
- Trial name
- NCT03477266
- Testing
- Mosapride
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Benha University
Solid Tumour, Postoperative Nausea and Vomiting
Ramosetron, Aprepitant and Dexamethasone (RAD) in Solid Cancer
Cisplatin is one of the most emetogenic drugs used in clinical practice and it could result in poor compliance with chemotherapy.
- Trial name
- RAD (NCT01046461)
- Testing
- Ramosetron, Aprepitant, Dexamethasone
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Hallym University Medical Center
Post Operative Pain, Nausea and Vomiting, Postoperative
Preoperative Intravenous Fluid Type and Postoperative Nausea
In this study, it was aimed to investigate the relationship between postoperative nausea and vomiting, anxiety levels and pain scores in the postoperative period according to dosing and choosing of intravenous fluid type that the…
- Conditions
- Post Operative Pain, Nausea and Vomiting, Postoperative, Anxiety
- Trial name
- NCT05961722
- Testing
- preoperative IV 0.9% saline 400 ml, preoperative dextrose 5% 400 ml, preoperative and intraoperative dextrose 5% 400 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pain, Postoperative Nausea
Postoperative Outcomes After Positive Intraoperative Messages
The patients scheduled for laparoscopic cholecystectomy will be allocated to 3 groups. Group A and B patients will listen to a positive message under general anesthesia. Group C patients will not listen to the message.
- Conditions
- Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT02765750
- Testing
- Intraoperative positive messages, No message
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- 424 General Military Hospital
Postoperative Nausea and Vomiting (PONV), Nausea
Aprepitant Versus Ondansetron in Preoperative Triple-therapy Treatment of Nausea and Vomiting
This study is being done to determine the efficacies of two preventative drug combinations for postoperative nausea and vomiting in patients undergoing neurosurgery.
- Trial name
- NCT01474915
- Testing
- Aprepitant, Ondansetron, Promethazine
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Sergio Bergese
PONV
Aprepitant to Improve Same Day Discharge for TKA
The purpose of this research is to study whether adding an FDA approved medication called aprepitant (a medication given to patients like you to reduce or eliminate nausea and vomiting) to the usual treatment to prevent nausea…
- Trial name
- NCT07639723
- Testing
- Aprepitant Injection, Ondansetron (Zofran), Dexamethasone
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Endeavor Health
Opioid-Free Anesthesia, Elective Laparoscopic Cholecystectomy
Effect of Opioid-Free Anesthesia (OFA) on Postoperative Pain and Perioperative Nausea and Vomiting in Elective Laparoscopic .
1. To evaluate the efficacy of a standardized multimodal Opioid Sparing (OS) protocol versus conventional opioid-based analgesia in reducing acute postoperative 2.
- Trial name
- OFA (NCT07306910)
- Testing
- opoid free anesthesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cholelithiasis
Effect of Acupuncture on Postoperative Nausea and Vomiting
The aim of the study is to investigate if P6 acupuncture made after induction of general anaesthesia might be effective for the prevention of PONV as ondansetron and if the acupuncture-ondansetron combination could enhance single…
- Trial name
- NCT00674713
- Testing
- Acupuncture, Ondansetron, Physiological saline solution
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Catholic University of the Sacred Heart
Postoperative Nausea and Vomiting
Palonosetron Versus Ramosetron for the Prevention of Postoperative Nausea and Vomiting
Ramosetron and palonosetron are more recently developed 5-hydroxytryptamine type 3 receptor antagonists and this randomized double blind study was designed to compare efficacy of ramosetron and palonosetron to prevent…
- Trial name
- NCT01476280
- Testing
- palonosetron, Ramosetron
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Incheon St.Mary's Hospital
Postoperative Nausea
How Pregnant Women and Their Babies Metabolize Ondansetron Compared to a Group of Non-pregnant Women
This is called "Aim 1" of the investigators' NIH grant. Ondansetron (Zofran) is a safe and effective drug used in pregnant women to prevent nausea but the investigators do not know what effect pregnancy may have on the metabolism…
- Trial name
- Zofran_PK (NCT01801475)
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Pain, Postoperative, Postoperative Nausea and Vomiting
Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Scoliosis
- Trial name
- NCT01531439
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Children's Mercy Hospital Kansas City
Quality of Recovery, Same Day Surgery
Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
To the investigators knowledge there are no studies in the literature evaluating the effect of Dexamethasone administration on patients undergoing outpatient vaginal prolapse surgeries.
- Conditions
- Quality of Recovery, Same Day Surgery, Nausea and Vomiting, Postoperative, Vaginal Prolapse
- Trial name
- NCT03338400
- Testing
- Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The Cleveland Clinic
Thyroid Diseases
Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery
Thyroid surgery requires smooth emergence from anesthesia to minimize coughing, hemodynamic fluctuations, and agitation during extubation, which may contribute to postoperative complications such as bleeding or cervical hematoma.
- Trial name
- DEX-THYROID (NCT07462195)
- Testing
- Dexmedetomidine, Standard General Anesthesia
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- Bach Mai Hospital
Postoperative Nausea, Vomiting
Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery
The goal of this clinical trial is to compare frequency with postoperative nausea and vomiting in ASA( American Society of Anesthesiologists) I, II patients undergoing laparoscopic surgery.
- Trial name
- PONV (NCT05632224)
- Testing
- Aprepitant, Granisetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
Postoperative Pain, Postoperative Nausea and Vomiting
High-Dose Steroid for Knee Arthroplasty
The purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Kneesurgery with Arthroplasty and the effect on postoperative pain and postoperative…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Knee Osteoarthritis, Perioperative/Postoperative Complications
- Trial name
- NCT03758170
- Testing
- Dexamethasone
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Nausea and Vomiting Post-foregut Surgery
Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut Surgery
The effect a ReletexTM device has on postoperative nausea and vomiting when used with ondansetron after foregut surgery will be studied.
- Trial name
- Reletex (NCT01510379)
- Testing
- Reletex, IV ondansetron 4 mg q 6 hours for a total of 4 doses, IV promethazine 25 mg q 6 hours prn
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kyle A Perry
Postoperative Nausea and Vomiting, Cardiovascular Surgical Procedures
Propofol Infusion and PONV in Cardiac Surgery
The aim of this observational cohort study is to evaluate the effect of high-dose versus low-dose propofol infusion on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing coronary artery bypass…
- Trial name
- nausea vomitng (NCT07386379)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Nausea and Vomiting
Aprepitant for Postoperative Nausea and Vomiting in Laparoscopic Hysterectomy
Gynecological surgery is associated with a high incidence of postoperative nausea and vomiting. NK1 receptor antagonists such as aprepitant appear to be highly effective for treating acute and delayed emesis, and yet…
- Trial name
- NCT01440673
- Testing
- Aprepitant
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gachon University Gil Medical Center
Inguinal Hernia
Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
the study aimed to investigate the effect of Iv nalbuphine on postoperative nausea and vomiting and pain with intrathecal morphine on inguinal hernia repair surgery.
- Trial name
- NCT05704673
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
This study will compare two different drug regimens (oral dronabinol versus intravenous ondanseteron) for the prevention of post-operative nausea and vomiting (PONV).
- Trial name
- PONV (NCT00757822)
- Testing
- Dronabinol, Ondansetron
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development