Clinical trials: Postoperative Surgical Scar
Surgical Incision, Surgery--Complications
Zinc Oxide Versus Petrolatum Following Skin Surgery
Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this…
- Conditions
- Surgical Incision, Surgery--Complications, Surgical Wound, Surgical Site Infection
- Trial name
- NCT03561376
- Testing
- Topical zinc oxide vs. petrolatum post-surgical scars
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melissa Pugliano-Mauro
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng
Scarring
Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring
The purpose of this study is to evaluate the effectiveness of dHACM in reducing scar tissue formation in craniectomy patients as well as facilitating reoperation and repair.
- Trial name
- NCT02033824
- Testing
- dHACM, Craniectomy
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- MiMedx Group, Inc.
Surgical Site Infection, Cosmetic Appearance of Cesarean Scar
Prospective Study on Cesarean Wound Outcomes
This study will investigate whether the placement of silver impregnated dressings beginning in the OR will improve wound healing in patients undergoing cesarean delivery compared to traditional Telfa pads.
- Conditions
- Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
- Trial name
- NCT01697748
- Testing
- Silver-impregnated dressing, Telfa pad dressing
- Where
- 3 sites in United States
- Volunteers
- 660 people
- Sponsor
- University of South Florida
Hoarseness, Dysphonia
A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring
The overall aim of the project is to develop a new method for treatment of untreatable severe hoarseness due to vocal fold scarring by local injection of autologous mesenchymal stromal cells (MSC).
- Conditions
- Hoarseness, Dysphonia, Aphonia, Vocal Fold Scar
- Trial name
- NCT04290182
- Testing
- MSC-KI-PL-204
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Karolinska University Hospital
Skin Wound Healing After Cesarean Section, Cesarean Section Scar Healing
Tissue-Engineered Construct Based on Amniotic Membrane and Calcium Alginate for Cesarean Section Wound Healing
This clinical trial aims to evaluate the safety and efficacy of an experimental tissue-engineered construct (TEC) based on amniotic membrane and calcium alginate for promoting epithelialization and improving scar quality in…
- Trial name
- NCT07241013
- Testing
- Tissue-engineered construct based on amniotic membrane and calcium alginate (TEC)
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Thumb Joint Stiffness
Electrical Stimulation to Recover Greater Range of Motion After Surgery
Background One of the potentially debilitative complications of operative repair and subsequent immobilization is stiffness that appears secondary to inflammation and adhesions.
- Trial name
- NCT01082432
- Testing
- electrically induced muscle activation
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Joseph Fourier
Adhesions, Colectomy
SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery
The purpose of this study is to determine if the use of SurgiWrapTM: (1) prevents/lowers the incidence of Grade 2 or higher soft tissue attachments under the incision made during abdominal surgery, (2) reduces post-operative…
- Trial name
- NCT00531739
- Testing
- Polylactic Acid Sheet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cytori Therapeutics
Wound Healing
Plasma Therapy for Scar Management
This study is a prospective, multicenter, real-world observational study. It aims to evaluate whether adding plasma device therapy to standard scar care is effective and safe for treating various types of scars, including…
- Trial name
- NCT07548593
- Testing
- Plasma Device
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Wound of Skin, Wound Heal
Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting
The aim of this study is to compare negative pressure wound therapy to traditional care after split-thickness skin grafting in patients aged over 18.
- Conditions
- Wound of Skin, Wound Heal, Wound, Wound Open
- Trial name
- TRUTH (NCT03649308)
- Testing
- Negative Pressure Wound Therapy, Conventional treatment
- Where
- 2 sites in Finland
- Volunteers
- 160 people
- Sponsor
- Central Finland Hospital District
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Breast Cancer
Does Scar Massage Improve Postoperative Pain and Function in Women With Breast Cancer?
All patients undergoing breast cancer surgery are left with scars which can significantly affect their physical and psychological well being.
- Trial name
- NCT00175344
- Testing
- Scar massage.
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Surgical Scar, Postoperative Scar
Impact of Perioperative Antibiotic Use on Surgical Scarring
This retrospective observational cohort study will evaluate whether perioperative antibiotic use is associated with long-term surgical scar outcomes.
- Trial name
- PASS (NCT07741591)
- Testing
- Perioperative Antibiotic Exposure
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Scars
Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance
Multicenter, double-blind study comparing SLI-F06 to vehicle formulation buffer for the improvement in scar appearance and wound strength in routine surgical excisions, as well as post-operative abdominoplasty scar appearance.
- Trial name
- NCT03880058
- Testing
- SLI-F06, Formulation buffer
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Scarless Laboratories, Inc.
Cesarean Section
The Effect of Amniotic Membrane Application on Post-Cesarean Wound Healing and Cosmetic Outcomes
This clinical trial evaluates the effectiveness of amniotic membrane application during cesarean delivery in reducing post-surgical complications and improving wound healing and cosmetic outcomes in women aged 18-40 undergoing…
- Trial name
- Amniotic Membr (NCT06770946)
- Testing
- Amniotic Membrane Application
- Where
- Turkey (Türkiye)
- Volunteers
- 372 people
- Sponsor
- Yuzuncu Yil University
Keloid
Compressive Device to Prevent Keloïd Scars Recurrence [SCARWARS]
SCARWARS study deals with the first on-human evaluation of a compressive device dedicated to the prevention of keloïd scars recurrence after surgery. The tested device is made with clinical grade silicon.
- Trial name
- SCARWARS (NCT03312166)
- Testing
- Compression device
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cicatrix, Scars
Study of the Effects of the Pulsed-dye Laser at 585nm and 595nm to Treat Post-operative Scars on Suture-removal Day
The purpose of this study is to compare the effects of the pulsed-dye laser (PDL) at two different wavelengths, 585nm and 595nm, in the treatment of post-surgical scars starting on suture-removal day.
- Trial name
- NCT00482144
- Testing
- PDL 450 microseconds, PDL 1.5 milliseconds
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Scar, Breast Neoplasms
Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery
All patients undergoing breast biopsy, lumpectomy, needle-localization-guided breast biopsy, and mastectomy at Einstein Medical Center Philadelphia, Einstein Medical Center Montgomery, Center One, or Einstein Elkins Park will be…
- Conditions
- Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
- Trial name
- NCT04554316
- Testing
- Steri-strip
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Gastroschisis, Neonatal Disease
Surgical Management Of Gastroschisis
The investigators aim to analyze the management of children born with gastroschisis between January 2009 and December 2023, i.e.
- Conditions
- Gastroschisis, Neonatal Disease, Hernia, Umbilical, Complication,Postoperative
- Trial name
- LAPS (NCT06461325)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand