Clinical trials: Postoperative Sleep Disturbances
Preoperative Sleep Disorder, Preoperative Anxiety
Relationship Between Perioperative Related Factors and Inflammatory Markers and Postoperative Delirium in Elderly Patients With Non-cardiac Major Surgery
Perioperative neurocognitive impairment, including postoperative delirium (POD), is common in older patients after anesthesia and surgery and is associated with poorer short- and long-term outcomes, including worsening cognitive…
- Conditions
- Preoperative Sleep Disorder, Preoperative Anxiety, Inflammatory Reaction, Postoperative Delirium
- Trial name
- NCT05341531
- Testing
- elderly patients undergoing non-cardiac surgery
- Volunteers
- 400 people
- Sponsor
- Beijing Friendship Hospital
Obstructive Sleep Apnea, Postoperative Analgesia
Oliceridine Versus Sufentanil Analgesia for Postoperative Patients With Obstructive Sleep Apnea
Opioids are frequently used for postoperative analgesia but may induce side effects. Opioid-induced respiratory depression is the most dangerous side effect of opioids.
- Conditions
- Obstructive Sleep Apnea, Postoperative Analgesia, Oliceridine, Sufentanil
- Trial name
- OSA (NCT07753785)
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 851 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea
The Incidence of Undiagnosed OSA Compared in Multi-ethic Races of Malaysia & the Associated Postoperative Complications
Obstructive sleep apnoea (OSA) is a condition in which a person's sleep is disrupted with momentary periods of apnoea and hypopnoea. This occurs when there is a blockage to airflow.
- Trial name
- NCT02127099
- Where
- Malaysia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postoperative Delirium
Relationship Between Perioperative Sleep Disturbance and Postoperative Delirium
The investigators are performing this research study to understand the role of sleep disturbance on the incidence of delirium after surgery.
- Trial name
- NCT05457387
- Where
- China
- Volunteers
- 11,927 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Delirium, Preoperative Sleep Disorder
Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients
Delirium is a common consequence of cardiac surgery and associates with poor outcomes. Multiple causes can trigger delirium occurence, and it has been hypothesised that sleep disturbances can be one of them.
- Trial name
- DREAMS (NCT06619912)
- Testing
- Dexmedetomidine nasal spray
- Where
- China
- Volunteers
- 686 people
- Sponsor
- Xijing Hospital
Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery
Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period
Patients undergoing gynecological surgery are at high risk of developing postoperative sleep disorders. Intraoperative opioid use is detrimental to the patient's postoperative recovery of gastrointestinal function.
- Trial name
- NCT05715671
- Testing
- esketamine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhuan Zhang
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University
Postoperative Sleep Disturbances, Chronic Post-surgical Pain
Effectiveness of Perioperative Percutaneous Acupuncture on Postoperative Sleep Disturbances and Chronic Pain in Patients Undergoing Video-Assisted Thoracoscopic Lung Cancer Resection: A Prospective, Randomized, Single-Blind, Superiority Controlled Trial
This study evaluates whether acupuncture at specific body points before and after surgery can improve sleep quality and reduce long-term postoperative pain in patients undergoing video-assisted thoracoscopic lung cancer…
- Trial name
- PASA-VATS (NCT07662733)
- Testing
- Percutaneous Acupoint Acupuncture
- Where
- 2 sites in China
- Volunteers
- 316 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Postoperative Pain Management in Total Knee Arthroplasty
EFFECT OF ZOLPIDEM ON SLEEP QUALITY AND OPIOID CONSUMPTION FOLLOWING PRIMARY TOTAL KNEE ARTHROPLASTY: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
This clinical trial evaluated whether zolpidem could improve sleep quality and postoperative recovery in patients undergoing total joint arthroplasty.
- Trial name
- NCT07801742
- Testing
- Zolpidem 10 mg tablets, Avocado-soybean unsaponifiables 300 mg
- Where
- Argentina
- Volunteers
- 54 people
- Sponsor
- Sanatorio Allende
Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS)
The SNORE-trial: Analysis of Alterations in Sleep Stages Following Anesthesia and Their Relation to the Severity of Obstructive Sleep Apnea in the First 3 Nights After Surgery
The goal of this observational study is to learn about the relationship between sleep alterations following anesthesia and their relationship to a potential increase of obstructive sleep apnea (OSA) severity.
- Trial name
- SNORE (NCT06586268)
- Where
- 2 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anesthesia, Surgery
General Versus Regional Anesthesia and Postoperative Sleep Quality
Major surgery can lead to postoperative disturbances in sleep patterns with subjective deterioration of sleep quality according to patients' reports as well as objective alterations of sleep architecture, as recorded by…
- Conditions
- Anesthesia, Surgery, Sleep Disturbance, Sleep Disorder
- Trial name
- AnesthSleep (NCT03843645)
- Testing
- general anesthesia, regional anesthesia
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
High Flow Nasal Cannula, Obstructive Sleep Apnea
High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea
This study aims to compare the effectiveness of conventional oxygen therapy oxygen and high-flow nasal cannula therapy on oxygen saturation (SpO2), measuring number of SpO2 drop >4% of base line oxygen saturation (o2 desaturation…
- Trial name
- NCT06306651
- Testing
- High flow nasal cannula therapy group, Conventional oxygen therapy group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Rotator Cuff Injuries, Postoperative Pain
Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair
The goal of this clinical study is to learn if using a special pillow placed behind the shoulder can help to reduce pain and improve sleep for patients after surgery to repair a torn rotator cuff.
- Conditions
- Rotator Cuff Injuries, Postoperative Pain, Sleep Quality
- Trial name
- NCT07372222
- Testing
- Posterior Shoulder Pillow, Conventional Rehabilitation Protocol
- Volunteers
- 126 people
- Sponsor
- Peking University Third Hospital
Dysphagia, Sleep Apnea, Obstructive
The Effect of Obstructive Sleep Apnea Operations on the Swallowing Function
The investigators hypothesize that partial robotic tongue base resection surgery and / or soft palate surgery, as a treatment for sleep apnea affect the swallowing quality.In order to characterize the dysphagia The investigators…
- Trial name
- NCT03082170
- Testing
- FEES, SDQ, data review
- Volunteers
- 120 people
- Sponsor
- Rambam Health Care Campus
Elderly, Surgery
Impact of Dexmedetomidine on Sleep Quality
Sleep disturbances frequently occur in elderly patients after major surgery; and their occurrence are associated with worse outcomes including increased incidence of delirium.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03117790
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea, Sleep Disordered Breathing
Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea
In this study the investigators will determine whether using high flow oxygen in moderate-to-severe Obstructive Sleep Apnea patients following a major non cardiac surgery is more efficacious than usual care in preventing decrease…
- Trial name
- POSAII (NCT03964376)
- Testing
- Nasal High Flow, Usual Care
- Where
- 8 sites in Canada, Hong Kong and 2 more
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Transcutaneous Electrical Acupoint Stimulation, Postoperative Sleep Disturbances
TEAS on Sleep Quality and POCD in Elderly Patients
Elderly patients are often considered as a high-risk population for major abdominal surgery due to reduced functional reserve and increased comorbidities.
- Conditions
- Transcutaneous Electrical Acupoint Stimulation, Postoperative Sleep Disturbances, Postoperative Cognitive Dysfunction, Elderly Patients
- Trial name
- NCT04850196
- Testing
- TEAS, control group
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Circadian Rhythm, Postoperative Sleep Disturbance
Effect of Esketamine on Postoperative Sleep in Postmenopausal Women
The prevalence of sleep disturbance among postmenopausal women has been reported to reach 51.6%. Epidemiological studies consistently show that the incidence of sleep disorders increases with age and menopausal transition.
- Trial name
- NCT07315074
- Testing
- Esketamine, Normal Saline
- Where
- 2 sites in China
- Volunteers
- 164 people
- Sponsor
- Zhuan Zhang
Sleep Disturbance
Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety
To explore and compare the effects of esketamine and remimazolam on postoperative sleep disturbance in patients undergoing oocyte retrieval
- Trial name
- NCT06284668
- Testing
- normal Saline, Esketamine, Remimazolam
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Tianjin Medical University General Hospital
Postoperative Sleep Disturbance
Dynamic Prediction of Sleep Protection Demand on the First Postoperative Night and Its Influence on Ward Process After Thoracoscopic Lobectomy or Segmentectomy
This study combines retrospective data analysis with a single-center prospective non-interventional cohort study to understand postoperative sleep disturbance on the first night after video-assisted thoracoscopic (VATS) lobectomy…
- Trial name
- NCT07716085
- Testing
- Video-assisted thoracoscopic (VATS) lobectomy or segmentectomy
- Volunteers
- 400 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine