Clinical trials: Postoperative Scar
Chronic Pain
Incidence and Associated Factors of Persistent Postoperative Incision Scar Pain Following C/s in Mulago Hospital
prospective cohort study of women who underwent caesarean section in mulago hospital. followed up for 2 months and assessed for development of persistent post operative pain at the incision site and its effect on quality of life.
- Trial name
- PPOPinC/S (NCT03269188)
- Volunteers
- 277 people
- Sponsor
- Makerere University
Surgical Scar
The Management of Surgical Scars Around Knee After Pediatric Orthopedic Surgery: an Observational, Case-control Study
Scar is an unpleasant symptom that commonly appear after orthopedic surgery, especially the joint procedure. Due to the wide motion range, skin around joint has excessive tension that may increase risk for wide or conspicuous…
- Trial name
- NCT04928443
- Testing
- Scar dressing group, Regular care group
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Caesarean Wound, Hypertrophic Surgical Scar
: Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section
This study aimed to evaluate the effectiveness of Protescal in preventing post caesarean section hypertrophic scar and keloid formation.
- Conditions
- Caesarean Wound, Hypertrophic Surgical Scar, Keloid Scar Following Surgery
- Trial name
- NCT04951869
- Testing
- Protescal gel
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Scar, Surgical Scar
Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars
The purpose of this study is to evaluate the safety and efficacy of the 532nm potassium titanyl phosphate (KTP) laser in comparison with the 595nm pulsed-dye laser (PDL) for the treatment of fresh surgical scars.
- Conditions
- Scar, Surgical Scar, Cicatrix, Cicatrix, Hypertrophic
- Trial name
- NCT01789346
- Testing
- 532nm KTP, 595nm PDL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cutera Inc.
Cleft Lip Post-surgical Scar
Assessment of Fractional CO2 Laser in Treatment of Post-surgical Scarring of Cleft Lip
This is a prospective comparative study on 120 patients divided to three groups. Group A: 40 patients laser will be applied 3 weeks post-surgical. Group B: 40 patients laser will be applied 3 months post surgical.
- Trial name
- NCT03277287
- Testing
- Fractional CO2 laser
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Corneal Scars and Opacities
Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze
This is a investigator-initiated pilot clinical trial to ascertain the safety and efficacy of application of ex-vivo cultivated limbal stem cells in human eyes for treating Corneal Haze after Photo-Therapeutic/Refractive…
- Trial name
- NCT03295292
- Testing
- Stem cells, Vehicle
- Where
- India
- Volunteers
- 15 people
- Sponsor
- L.V. Prasad Eye Institute
Wound Healing Disorder, Post-Surgical Complication
NovoX®Cup as Primary Dressing After Breast Reduction
Breast reduction is one of the most frequently performed plastic surgeries. Studies have shown that breast reduction surgery significantly improves the patients' suffering and leads to a better health-related quality of…
- Conditions
- Wound Healing Disorder, Post-Surgical Complication, Mammaplasty
- Trial name
- NCT06420323
- Testing
- Treatment with NovoX® Cup, Treatment with Omnistrip®
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- MOSS S.p.A.
Scar
Postoperative Skin Surface Tension Relaxing in Prevention of Facial Surgical Skin Scarring
The purpose of this study is to evaluate the efficacy and safety of early postoperative skin surface reduction in improving scar formation after facial surgery.
- Trial name
- NCT03842644
- Testing
- Tension reduction device
- Where
- China
- Volunteers
- 55 people
- Sponsor
- XiaoXi Lin
Burn Scar, Burn Wound
Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients
The goal of this study is to see how an ingredient called kynurenic acid (which we named "FS2") affects scar formation in people with burn injuries that need skin graft surgery.
- Trial name
- NCT06807021
- Testing
- IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Birch BioMed Inc
Surgical Scar Erythema
COEBICS: Comparison of Erythema Between Interrupted and Continuous Sutures
This is a randomized, controlled, prospective study which relies on computer-assisted skin image processing of scar photographs, to establish whether simple interrupted or running sutures are associated with the greatest degree…
- Trial name
- COEBICS (NCT02997306)
- Testing
- Superior/Medial Running Sutures, Inferior/Lateral Running Sutures
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Postoperative Surgical Scar, Scar
Effect of an Intraoperative Polynucleotide Injection on Scar Quality After Thyroidectomy
The goal of this clinical trial is to learn whether a single polynucleotide injection can improve scar quality after thyroid or parathyroid surgery in adults. It will also assess the safety of the injection.
- Conditions
- Postoperative Surgical Scar, Scar, Scar Formation, Neck Scar
- Trial name
- NCT07791953
- Testing
- Polynucleotide (PN-HPT), Sterile 0.9% Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Scar
Disposable Noninvasive Skin Closure for Promoting Postoperative Wound Healing and Preventing Surgical Skin Scarring
The purpose of this study is to evaluate the efficacy and safety of a disposable noninvasive skin closure device in promoting postoperative wound healing and reducing surgical scar formation.
- Trial name
- NCT07849010
- Testing
- Disposable Noninvasive Skin Closure Device (Shanghai Zhizhong Medical Technology Co., Ltd. Catalog No.: 240430PFF)
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Peking University Third Hospital
Keloid
Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181
The objective of the study is to evaluate the initial safety and efficacy of MF-4181, a hydrogel scaffold, in the reduction of the volume, appearance, and/or symptoms associated with keloid scarring in subjects undergoing…
- Trial name
- NCT01446770
- Testing
- Hydrogel scaffold (MF-4181)
- Where
- The Bahamas
- Volunteers
- 19 people
- Sponsor
- Halscion, Inc.
Scar
Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection
Linear hypertrophic scar is a common surgical problem that can be difficult to manage, especially for the median sternotomy scar.
- Trial name
- NCT02886988
- Testing
- Botulinum toxin type A, normal saline
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Xijing Hospital
Scars
Efficacy Study of Two Silicon-based Products to Treat Scars
This study aims to determine if a silicon-based gel and a silicon-based aerosol are effective in the treatment of postoperative scars.
- Trial name
- Kelofin (NCT02584010)
- Testing
- Silicon-based aerosol, Silicon-based gel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cesarean Section Wound, Platelet-rich Plasma (PRP)
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicine to promote healing and…
- Conditions
- Cesarean Section Wound, Platelet-rich Plasma (PRP), Regenerative Medicine
- Trial name
- PRP06081992 (NCT06978010)
- Testing
- Platelet-Rich Plasma (PRP) intraoperatively
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Breast Cancer
Does Scar Massage Improve Postoperative Pain and Function in Women With Breast Cancer?
All patients undergoing breast cancer surgery are left with scars which can significantly affect their physical and psychological well being.
- Trial name
- NCT00175344
- Testing
- Scar massage.
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Scar Tissue, Hypertrophic Scar
Effectiveness of Dry Needling in Linear Scar Tissue
Scar tissue can cause serious complications that significantly impact a patient's quality of life. Common complications include stiffness and contractions, which can restrict joint mobility and make daily activities challenging.
- Conditions
- Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar
- Trial name
- NCT06033430
- Testing
- True dry needling
- Where
- 2 sites in United States, Iran
- Volunteers
- 80 people
- Sponsor
- Iran University of Medical Sciences
Brow Ptosis, Facial Scarring
The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair
This is a double (physician and patient) blinded randomized controlled clinical trial in which patients who have undergone bilateral direct brow ptosis repair undergo a trial in which one of brow is injected with placebo 0.9%…
- Trial name
- NCT03219580
- Testing
- 5-Fluorouracil, Normal Saline Flush, 0.9% Injectable Solution
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eyelid and Facial Consultants