Clinical trials: Postoperative Pain Control
Pain
Local Continuous Wound Infusion of Anesthetics in the Management of Post-operative Pain After Total Hip Arthroplasty.
The combination of subarachnoid anaesthesia (SAB) and continuous local wound infiltration (LCWI) with a consistent amount of local anaesthetics could prevent central sensitization through an additive or synergistic effect because…
- Trial name
- NCT02728310
- Testing
- Levobupivacaine, Saline
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- San Salvatore Hospital of L'Aquila
Postoperative Pain, Postoperative Return of Bowel Function
Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Sections
Postoperative discomfort is a frequently seen adverse event after to caesarean operation. Early mobilization and bonding of the mother and her infant are typically impacted by this phenomenon.
- Trial name
- NCT06433713
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Pain, Third Molar
Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.
The operation of the lower third molars is one of the most common oral surgery procedures in the world. The surgery is mostly done in local anesthesia which makes the surgery as pleasant as possible for the patient.
- Conditions
- Postoperative Pain, Third Molar, Postoperative Complications
- Trial name
- NCT03398382
- Testing
- Magnesium tablet group, Magnesium lozenge group
- Where
- 2 sites in Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniel Jerković
Total Knee Replacement
Effects of Combined Topical and Systemic Steroid Administrations on Better Early Postoperative Pain Management in Total Knee Arthroplasty
With the aging of population, osteoarthritis of knees and hips has become major orthopaedic problems in Hong Kong. Osteoarthritis of knees and hips is associated with significant pain problems and functional disability.
- Trial name
- NCT03901768
- Testing
- Dexamethasone, Triamcinolone
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Post Operative Pain Control, Narcotic Use
Sprix for Postoperative Pain Control Following Gynecologic Surgery
The ongoing opioid epidemic has altered both how physicians prescribe narcotics and patients' perceptions of those prescriptions.
- Conditions
- Post Operative Pain Control, Narcotic Use, Pelvic Organ Prolapse, Urinary Incontinence , Stress
- Trial name
- NCT04444830
- Testing
- Sprix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Post-operative Pain
CBD Knee Scope Study
This is a prospective, randomized, nonblinded trial to evaluate the effectiveness of Cannabidiol (CBD) oil on post-operative pain control compared to opioid medications after a knee arthroscopy.
- Trial name
- CBDS (NCT05934500)
- Testing
- Cannabidiol Oil
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Post Operative Analgesia
ERECTOR SPINAE BLOCK AFTER THORACIC SPINE SURGERY
the effectiveness of ultrasound guided erector spinae plane block in patients undergoing thoracic spine sugery
- Trial name
- SPINE (NCT04449367)
- Testing
- ultrasound guided erector spinae plane block
- Where
- United Arab Emirates
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dubai Health Authority
Teeth, Impacted
Bupivacaine in the Treatment of Postoperative Pain of Impacted Third Molar Extraction
The third molars are the teeth that are most frequently included and impacted, extraction is one of the most performed treatments by maxillofacial surgeons in their clinical practice.
- Trial name
- NCT03950700
- Testing
- Bupivacaine-epinephrine, Saline Solution
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Thoracoscopic Surgeries
Erector Spine Plane Block Versus Single-injection Thoracic Paravertebral Block Via Intrathoracic Approach in Single-port Video-assisted Thoracoscopic Lung Surgeries
Effect of ultrasound-guided erector spine plane block versus single-injection thoracic paravertebral block via intrathoracic approach in single-port video-assisted thoracoscopic lung surgeries in postoperative analgesia: a…
- Trial name
- VAT (NCT06160375)
- Testing
- pain assessment after video assisted thoracoscopic lung surgeries
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative
Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial.
- Trial name
- NCT04260854
- Testing
- Bupivacaine Hydrochloride, Saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postoperative Pain Management, Total Knee Arthroplasty
Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal Morphine
To evaluate whether pregabalin and/or celecoxib could improve analgesic efficacy of intrathecal morphine for patients after total knee arthroplasty.
- Trial name
- PCTKA (NCT01344213)
- Testing
- Pregabalin, Celecoxib, Pregabalin with celecoxib
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Mammaplasty
The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery
This project intends to more thoroughly investigate the direct influence of Pecs blocks in the administration of Exparel, a non-opioid analgesic, in breast reconstruction surgery.
- Trial name
- NCT05171179
- Testing
- Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative
Erector Spinae Plane Block in Liver Transplantation Donors
Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision.
- Trial name
- NCT05406388
- Testing
- Erector Spinae Plane Block, Intravenous fentanyl patient control device
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medipol University
Pain, Postoperative, Opioid Use
Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial
Major abdominal surgery continues is one of the most performed surgical procedures in the world, both electively and urgently. One of the main problems of this type of intervention is postoperative pain.
- Trial name
- NCT04017013
- Testing
- Epidural Analgesia, Lidocaine Infusion
- Where
- Colombia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Opioid Pain Medication
Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation
This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term…
- Trial name
- NCT04814433
- Testing
- Tranexamic acid, Aminocaproic acid, Recombinant Human Thrombin
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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