Clinical trials: Postoperative Outcomes
URTI, Postoperative Complications
Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic
The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional…
- Conditions
- URTI, Postoperative Complications, COVID - 19, Elective Non-cardiac Surgery
- Trial name
- URTI (NCT07157111)
- Where
- China
- Volunteers
- 2,392 people
- Sponsor
- aijun xu
Urologic Cancer, Prostate
Comparison of the Integrated Posterior-Anterior-Lateral Approach and the Posterior Approach in Robotic Radical Prostatectomy
This study aims to compare perioperative, pathological, and early functional outcomes of PAL （Posterior, Anterior and Lateral）combined approach RARP and posterior approach (with Retzius space preserved) RARP in the treatment of…
- Conditions
- Urologic Cancer, Prostate, Robot Assisted Laparoscopic Radical Prostatectomy
- Trial name
- NCT07305142
- Testing
- PAL combined approach group, posterior approach group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Lung Cancers, Bone Metastasis
Spinal Metastasis as the First Presentation of Lung Malignancy: Clinical Characteristics and Postoperative Survival
The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an…
- Trial name
- NCT07100444
- Where
- China
- Volunteers
- 139 people
- Sponsor
- Guangdong Provincial People's Hospital
Colonic Neoplasms, Crohn's Disease
Single Port Colic Laparoscopic Surgery
This study aims to compare the results of colonic surgery performed by single and multiport laparoscopy.
- Conditions
- Colonic Neoplasms, Crohn's Disease, Diverticulitis
- Trial name
- TRUE (NCT01959087)
- Testing
- single port surgery, Multiport surgery
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Postoperative, Total Knee Arthroplasty
Duloxetine RCT on Postop TKA Outcomes
The aim of this study is to determine if duloxetine is associated with differences in post-operative pain, patient-reported outcome measures, and opioid consumption in patients undergoing primary total knee arthroplasty compared…
- Trial name
- NCT05086393
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteo Arthritis Knee and Hip, Osteo Arthritis
General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are common operations used to treat severe joint disease, most often caused by osteoarthritis.
- Conditions
- Osteo Arthritis Knee and Hip, Osteo Arthritis, Inflammatory Joint Disease (IJD)
- Trial name
- GASPS (NCT07334132)
- Testing
- General Anaesthesia, Spinal Anesthesia (bupivacaine)
- Volunteers
- 600 people
- Sponsor
- Region Örebro County
Bladder Cancer
Study of Outcomes After Surgery/Treatment to Treat Bladder Cancer
The purpose of this study is to create a registry of older patients undergoing surgical and/or medical treatment for bladder cancer.
- Trial name
- PORCH (NCT01776138)
- Testing
- Collect Blood and Survey Instruments
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Respiratory Rehabilitation
Pre-operative Respiratory Rehabilitation in Coronary Artery Bypass Graft Patients
To compare the effects of conventional preoperative respiratory rehabilitation and specific preoperative respiratory rehabilitation program on pulmonary functions in coronary artery bypass graft patients.
- Trial name
- NCT05736770
- Testing
- Respiratory rehabilitation and out of bed mobilization, conventional treatment
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Riphah International University
Pain
Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty
This study will determine whether a drug called sodium nitrite helps improve pain and post-operative recovery associated with knee replacement surgery.
- Trial name
- NCT05893160
- Testing
- JAN101 SR
- Sponsor
- University of Alabama at Birmingham
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Lung Cancer (Diagnosis)
AI-Personalized Discharge Education for Patients After Lung Cancer Surgery
This randomized controlled trial evaluates the effect of artificial intelligence (AI)-personalized discharge education on discharge teaching quality and recovery outcomes in patients after lung cancer surgery.
- Trial name
- AI-LUNG (NCT07827183)
- Testing
- AI-Personalized Discharge Education, Routine Discharge Education
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Xiamen University
Fluid Balance, Input and Output
Fluid Balance and Clinical Outcomes
This study is about investigating the relationship of postoperative fluid balance, inflammation and acute kidney injury. This is a non-interventional study (no drug administration).
- Conditions
- Fluid Balance, Input and Output, Inflammatory Mediators, Acute Kidney Injury
- Trial name
- NCT01168583
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Florida
Prehabilitation, Preoperative Care
Prehabilitation Before Major Surgery
The goal of this clinical trial is to learn if a virtually monitored, home-based prehabilitation program is feasible and acceptable for adults undergoing major elective surgery. The main questions it aims to answer are: 1.
- Conditions
- Prehabilitation, Preoperative Care, Elective Surgical Procedures, Postoperative Complications
- Trial name
- PRIME (NCT07590141)
- Testing
- Virtually Monitored Home-Based Prehabilitation Program
- Where
- 3 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Queen's University
Pancreas Neoplasm
Postoperative Outcomes After Partial Duodenopancreatectomy Versus Total Pancreatectomy
The goal of this observational study is to compare short-term outcomes after partial pancreatoduodenectomy and total pancreatectomy in adults undergoing elective surgery for pancreatic or periampullary neoplasms in Switzerland.
- Trial name
- NCT07831694
- Volunteers
- 3,602 people
- Sponsor
- Cantonal Hospital of St. Gallen
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Postoperative Respiratory Complications
Perioperative Respiratory Support and Postoperative Outcomes
This study aims to evaluate the methodology and parameters of perioperative respiratory support (RS) and the frequency of postoperative pulmonary complications (PPCs) in the Russian Federation.
- Trial name
- RuVent-A (NCT06798883)
- Volunteers
- 1,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Sinusitis
Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery
Sinusitis is a common medical problem, which significantly decreases patients' quality of life (QOL). Patients may have symptoms such as headaches, sinus pressure, nasal congestion and drainage, decreased sense of smell, and…
- Trial name
- NCT02900794
- Testing
- Gold Laser, Microdebridement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Mechanical Ventilation Complication, Surgery
Intraoperative Hypocapnia in PROVHILO and PROBESE
To gain a better understanding of the epidemiology of intraoperative hypocapnia, in particular the associations of intraoperative hypocapnia with patient demographics, ventilator characteristics, and perioperative complications…
- Conditions
- Mechanical Ventilation Complication, Surgery, Pulmonary Complication, Intraoperative Complications
- Trial name
- iHypoPRO (NCT05550181)
- Testing
- intraoperative mechanical ventilation with hypocapnia (etCO2 < 35 mm Hg)
- Where
- 4 sites in Brazil, Germany and 2 more
- Volunteers
- 2,793 people
- Sponsor
- NMC Specialty Hospital
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC