Clinical trials: Postoperative Mortality
Chronic Subdural Hematoma, Trendelenburg
Effect of the Postoperative Trendelenburg Position on Chronic Subdural Hematoma Recurrence
Objective: Determine the effect of the postoperative trendelenburg position on the recurrence of chronic subdural hematoma (CSH) in patients undergoing surgery.
- Conditions
- Chronic Subdural Hematoma, Trendelenburg, Recurrence, Mortality
- Trial name
- POTHeR (NCT06911736)
- Testing
- Trendelenburg position
- Where
- 3 sites in Colombia
- Volunteers
- 254 people
- Sponsor
- Universidad de Antioquia
Artificial Intelligence, Intensive Care Unit
Success of ChatGPT in Determining the Need for Postoperative Intensive Care
This is a prospective, observational study to be conducted at Sağlık Bilimleri University Istanbul Kanuni Sultan Süleyman Training and Research Hospital and Başakşehir Çam and Sakura City Hospital.
- Conditions
- Artificial Intelligence, Intensive Care Unit, PACU Length of Stay
- Trial name
- NCT06321328
- Where
- Turkey (Türkiye)
- Volunteers
- 406 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Myocardial Injury After Noncardiac Surgery (MINS), Bleeding Independently Associated With Mortality After Noncardiac Surgery (BIMS)
Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2
VISION-2 is an international, multi-site, prospective observational cohort study of 20,000 patients undergoing noncardiac surgery.
- Conditions
- Myocardial Injury After Noncardiac Surgery (MINS), Bleeding Independently Associated With Mortality After Noncardiac Surgery (BIMS), Sepsis, Infection Without Sepsis
- Trial name
- VISION-2 (NCT07300579)
- Testing
- Continuous vital signs measurement device
- Where
- 3 sites in Canada
- Volunteers
- 20,000 people
- Sponsor
- Hamilton Health Sciences Corporation
Vagus Nerve Stimulation, Acute Coronary Syndrome
Auricular Vagus Stimulation and STEMI
At the moment, the invasive strategy for the infarct-associated coronary artery in patients with ST-segment elevation myocardial infarction (STEMI) necessary to save the myocardium and reduce the size of the necrosis zone remains…
- Conditions
- Vagus Nerve Stimulation, Acute Coronary Syndrome, Ischemia Reperfusion Injury
- Trial name
- NCT05992259
- Testing
- TENS
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Hemoglobins, Albumins
Association Between Preoperative HALP and Immediate Postoperative Outcomes
Multiple inflammation-based prognostic scores have been developed for the prediction of perioperative morbidity and mortality following pancreaticoduodenectomy (PD).
- Conditions
- Hemoglobins, Albumins, Platelets, Lymphocytes
- Trial name
- NCT05506748
- Testing
- pantients undergoing pancreaticoduodenectomy
- Where
- Nepal
- Volunteers
- 22 people
- Sponsor
- Chitwan Medical College
Postoperative Complications
Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice
Patients with the lower malignant obstructive jaundice planned to do the pancreaticoduodenectomy, receiving preoperative biliary drainage or early surgery (without preoperative biliary drainage), both groups has the similar…
- Trial name
- NCT01744938
- Testing
- preoperative biliary drainage
- Volunteers
- 136 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Postoperative Pulmonary Complications
Postoperative Pulmonary Complications in Major Abdominal Surgery
Incidence of Postoperative Pulmonary Complications (PPCs) varies from 2% to 19%, according to the population under examination and the criteria used to define pulmonary complications. There is no univocal definition of PPCs.
- Trial name
- NCT01701908
- Where
- 40 sites in Italy
- Volunteers
- 1,542 people
- Sponsor
- University of Udine
Upper Gastrointestinal Disorders
CPET and Outcome After Oesophagogastric Cancer Surgery
Primary Aim: The present study is a retrospective analysis of prospectively collected clinical data. Anonymized data from patients collected during routine clinical care from 9 units in the United Kingdom who undertake upper…
- Trial name
- NCT03637647
- Testing
- Cardiopulmonary exercise testing
- Where
- United Kingdom
- Volunteers
- 611 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Postoperative; Dysfunction Following Cardiac Surgery
Is Six Weeks Too Long for First Outpatient Review After Cardiac Surgery?
Although the first outpatient review following cardiac surgery is conventionally scheduled for six weeks after hospital discharge, there is no evidence to support this practice.
- Trial name
- FORCAST6 (NCT02832427)
- Where
- United Kingdom
- Volunteers
- 85 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Postoperative Complications, Critical Illness
IL-6 and Hemogram-Derived Inflammatory Indices for Mortality Prediction in Postoperative ICU Patients
This prospective observational cohort study aims to evaluate the predictive value of interleukin-6 (IL-6) levels and hemogram-derived inflammatory scores for morbidity and in-hospital mortality in postoperative patients admitted…
- Conditions
- Postoperative Complications, Critical Illness, Inflammation, Intensive Care Unit Admission
- Trial name
- NCT07460141
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ezgi Günaydın
Subarachnoid Hemorrhage, Traumatic Brain Injury
Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy
Strict glycemic control improves mortality and morbidity of patients admitted to the postoperative intensive care unit (ICU). The investigators would like to know if this therapy could improve the long term neurologic and…
- Conditions
- Subarachnoid Hemorrhage, Traumatic Brain Injury, Intracranial Hemorrhage
- Trial name
- NCT00505505
- Testing
- Insulin (Actrapid)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- University of Roma La Sapienza
Surgery, Failure to Rescue
'5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation
'Failure to rescue' describes the preventable death of a patient following the absence of timely identification and treatment of a complication after surgery.
- Trial name
- NCT06997328
- Testing
- Implementation of the '5 Rs to Rescue'
- Where
- South Africa
- Volunteers
- 6,000 people
- Sponsor
- University of Cape Town
Hip Fractures
Postoperative Intervention Program Effectiveness in Hip Fracture Patients: A Randomized Clinical Trial
The aim of the study is to investigate whether a simple intervention improves the physical functioning and reduce mortality after surgery for elderly hip fracture patients in a period of one year follow up.
- Trial name
- NCT03156075
- Testing
- Nutrition and exercise program
- Volunteers
- 124 people
- Sponsor
- Dalia Mahran
Acute Kidney Injury, Major Surgery Under General Anesthesia
Risk Factors of Postoperative Acute Kidney Injury and Mortality Among Hospitalized Patients Undergoing Major Surgery
The goal of this retrospective observational study is to learn about the intervenable risk factors of postoperative acute kidney injury (AKI) and in-hospital mortality among adult patients undergoing major surgery.
- Conditions
- Acute Kidney Injury, Major Surgery Under General Anesthesia, Mortality, Postoperative Complication
- Trial name
- NCT07136194
- Where
- China
- Volunteers
- 21,533 people
- Sponsor
- Peking University First Hospital
Liver Regeneration
Platelets in Liver Regeneration
The most relevant factor predicting morbidity and mortality after liver resections is the ability of the remnant liver to regenerate.
- Trial name
- NCT02113059
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Surgery, Proteinuria
Postoperative New-onset Proteinuria and Adverse Outcomes.
We aimed to assess the association between postoperative new-onset proteinuria, all-cause mortality, and decline in kidney function in Chinese people who underwent surgery.
- Conditions
- Surgery, Proteinuria, Mortality
- Trial name
- NCT06339229
- Testing
- proteinuria
- Volunteers
- 2,983,899 people
- Sponsor
- Yaozhong Kong
Liver Resection, Anemia
Preoperative Anemia Affected to Postoperative Outcomes in Liver Resection
To assess the impact of preoperative anemia on postoperative outcomes in patients undergoing liver resection
- Conditions
- Liver Resection, Anemia, Postoperative Mortality and Morbidity
- Trial name
- NCT06905041
- Volunteers
- 728 people
- Sponsor
- Chiang Mai University
Postoperative Complications
Derivation and Validation of the Extended Care (Ex-Care) Model II
The goal of this study is to develop a novel surgical risk stratification tool designed to adults operated in Brazil. The main question it aims to answer is: •Is the Extended Care (Ex-Care) II model a good tool to assess the risk…
- Trial name
- Ex-CareII (NCT05796024)
- Where
- Brazil
- Volunteers
- 107,372 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Morbidity, Postoperative Mortality
Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Trial name
- FLASH (NCT02502773)
- Testing
- Hydroxethyl starch
- Where
- France
- Volunteers
- 826 people
- Sponsor
- University Hospital, Clermont-Ferrand