Clinical trials: Postoperative Depression
Postoperative Depression
Intravenous Esketamine on Prevention of Postoperative Depression in Patients Undergoing Cardiac Surgery
Esketamine is a general anesthetic with anti-depressant effects at subanaesthetic doses. This study hypothesized that intraoperative administration of ketamine would prevent or mitigate postoperative depressive symptoms in…
- Trial name
- NCT05155969
- Testing
- Esketamine, Normal saline
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Anshi Wu
Adolescent Idiopathic Scoliosis, Respiratory Depression
Anesthetic Optimization in Scoliosis Surgery
The standard anesthetic care plan for people having adolescent idiopathic scoliosis surgery will be accompanied by a pharmacokinetic simulation of the administered drugs to suggest opportunities to adjust drug doses to achieve…
- Conditions
- Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
- Trial name
- AIS (NCT02481570)
- Testing
- pharmacokinetic simulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Postoperative Cognitive Dysfunction, Hip Fractures
The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia
Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors.
- Conditions
- Postoperative Cognitive Dysfunction, Hip Fractures, Depression, Anxiety, Quality of Life
- Trial name
- NCT04518839
- Volunteers
- 140 people
- Sponsor
- University of Zagreb
Postoperative Depression
Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial
This protocol describes a feasibility trial that will evaluate the feasibility of conducting a full-scale phase 3 trial testing the hypothesis that a postoperative sustained, low-dose ketamine infusion can prevent postoperative…
- Trial name
- K-PASS (NCT05233566)
- Testing
- Ketamine, Normal saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Washington University School of Medicine