Clinical trials: Postoperative Complication
Knee Osteoarthritis, Pain, Postoperative
Influence of Patient Sex on Pain Control and Multimodal Analgesia in Total Knee Arthroplasty
The purpose of this study is to examine the influence of sex on postoperative pain, following total knee arthroplasty (TKA). Patients will first be stratified by sex and then be randomized into one of two multimodal analgesic…
- Trial name
- NCT04471233
- Testing
- Multimodal analgesia including pregabalin, Multimodal analgesia not including pregabalin
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Northwell Health
Femur Fracture, Periprosthetic Fracture of Hip
Dose-Response Association Between Cerclage Wire Number and Infection Risk
The purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections.
- Conditions
- Femur Fracture, Periprosthetic Fracture of Hip, Periprosthetic Fracture of the Femur, Surgical Site Infection (SSI)
- Trial name
- C-INFECT (NCT07434258)
- Testing
- 1 Metallic Cerclage Wiring, 2 metalic cerclage wire, 3 metalic cerclage wire
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Hip Arthropathy, Knee Arthropathy
Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications
Vitamin D status has been shown to have an effect on post-operative outcomes in total joint arthroplasty. The goal of this study is to determine if pre-operative supplementation and correction of Vitamin D deficiency can reduce…
- Conditions
- Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
- Trial name
- NCT04229368
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Brigham and Women's Hospital
Postoperative Complications
Presepsin as a Predictor for Postoperative Complications Following Pancreatic Resection
The study investigates the local and systemic inflammatory response following pancreatic resections.
- Trial name
- NCT04294797
- Testing
- Blood draw
- Where
- Austria
- Volunteers
- 86 people
- Sponsor
- Medical University Innsbruck
Non Shockable Out of Hospital Cardiac Arrest
Cyclosporine A in Cardiac Arrest
The investigators hypothesised that cyclosporine A administration at the onset of cardiopulmonary resuscitation, by inhibiting the mitochondrial permeability transition pore, could prevent the post cardiac arrest syndrome and…
- Trial name
- CYRUS (NCT01595958)
- Testing
- Cyclosporine A, cardio-pulmonary resuscitation
- Where
- France
- Volunteers
- 796 people
- Sponsor
- Hospices Civils de Lyon
Wound and Injuries, Surgical Wound Dehiscence
The Clinical Efficacy of RENASYS TOUCH NPWT System in the Management of Acute, Sub-acute and Chronic Wounds
The study is looking at the clinical efficacy, functionality and device performance of a new Negative Pressure Wound Therapy (NPWT) system in the management of a variety of wound types, in a real-life clinical setting.
- Trial name
- NPWT (NCT02565043)
- Testing
- RENASYS TOUCH Negative Pressure Wound Therapy System
- Where
- 2 sites in South Africa
- Volunteers
- 80 people
- Sponsor
- Smith & Nephew, Inc.
Delirium - Postoperative, Hip Fracture Surgeries
DEX-HIP Trial: Preoperative IV Dexamethasone 4 mg vs Placebo to Reduce Postoperative Delirium Burden in Adults ≥70 Undergoing Hip Fracture Surgery
This single-center, prospective, randomized, double-blind, placebo-controlled trial was conducted at the Department of Orthopaedic Surgery, JPMC, Karachi.
- Conditions
- Delirium - Postoperative, Hip Fracture Surgeries, Steroid
- Trial name
- NCT07651150
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Postoperative Pain
Effectiveness of Magnetic Therapy on Pain Intensity
Static magnetic therapy is increasingly used to alleviate pain; however, its efficacy has not been determined yet. The aims of this proposal are to evaluate the effect of magnetic therapy on pain intensity levels, opioid…
- Trial name
- NCT00104533
- Testing
- Magnets
- Where
- Colombia
- Volunteers
- 164 people
- Sponsor
- Javeriana University
Obesity, Morbid, Bariatric Surgery Candidate
Trends and Safety in Revisional Bariatric Surgery in Italy
Background: Revisional bariatric surgery (RBS) represents a further solution for patients who experience an inadequate response following initial bariatric surgery or significant weight regain following an initial satisfactory…
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Remission, Complication,Postoperative
- Trial name
- NCT05194943
- Testing
- revisional bariatric surgical procedures
- Where
- 11 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Roma La Sapienza
Bacterial Vaginoses
A Randomized Controlled Trial of Treatment of Bacterial Vaginosis
This is a double-blinded, placebo controlled, multi-center randomized trial of 482 pregnant women who are diagnosed with Bacterial Vaginosis (BV) in the late 3rd trimester (>34 weeks).
- Trial name
- NCT04578015
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Ohio State University
Pain, Postoperative, Anesthesia
Oral Methadone in Cardiac Surgery
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac…
- Conditions
- Pain, Postoperative, Anesthesia, Cardiac Surgery
- Trial name
- OMICS (NCT07221617)
- Testing
- Methadone, oral, Methadone, intravenously
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Lidocaine, Dexmedetomidine
Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV
BACKGROUND: Few researches have manifested that intravenous (IV) lidocaine or dexmedetomidine decreased the incidence of postoperative nausea and vomiting (PONV).
- Conditions
- Lidocaine, Dexmedetomidine, Nausea and Vomiting, Postoperative
- Trial name
- NCT03788018
- Testing
- lidocaine and dexmedetomidine IV, saline IV
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xu Siqi
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Post Operative Pain, Acute
Bupivacaine Alone vs Bupivacaine With Tramadol in Local Anesthesia Procedures
This study looked at two different medicines used during local anesthesia to control pain after surgery. Investigators compared bupivacaine alone with bupivacaine mixed with tramadol.
- Trial name
- NCT07469826
- Testing
- Tramadol, Bupivacaine
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Post Operative Pain, Acute, Arthroscopic Shoulder Surgery
Comparison Between Dexametidomedine\Bupivacaine and Plain Bupivacaine in Superior Trunk Block for Arthroscopic Shoulder Surgeries
Comparison between dexametidomedine\bupivacaine and plain bupivacaine in superior trunk block for arthroscopic shoulder surgeries
- Trial name
- NCT07046325
- Testing
- dexametedomidine, Bupivacain
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Thoracic Surgery, Postoperative Pulmonary Complications (PPCs)
Perioperative Inhaled Therapy in Carcinological Thoracic Surgery in Patients at High Risk of Postoperative Pulmonary Complications
The objective of the study is to evaluate, in a clinical trial, the efficacy of peri operative administration of long-acting inhaled ß-2 mimetics on the occurrence of postoperative pulmonary complications
- Trial name
- TICTAC (NCT06865040)
- Testing
- Formoterol Fumarate 12 mcg (Foradil Aerolizer), Usual treatment
- Where
- France
- Volunteers
- 266 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Delirium - Postoperative, Anxiety Acute
Pediatric Recovery Delirium in Pediatric Patients Undergoing Surgery
The primary aim of this observational study is to evaluate the effect of playing a mother's voice to a child while the patient is being awakened from anesthesia on postoperative delirium.
- Trial name
- Delirium (NCT07413289)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Pain, Postoperative
Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management…
- Trial name
- NCT04349774
- Testing
- Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Uskova