Clinical trials: Postoperative Atrial Fibrillation
Atrial Fibrillation, Coronary Artery Bypass Grafting
Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)
The purpose of this study is to determine whether postoperatively oral treatment with high dosis amiodarone for five days after intravenously admitted bolusinfusion will minimize the risk for development of atrial fibrillation…
- Trial name
- NCT00287209
- Testing
- Amiodarone
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Cardiac Surgery
Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
Over the past few years, research has focused on the prevention of atrial fibrillation (AF) after cardiac surgery, but highly effective interventions are still missing.
- Trial name
- BOTAF (NCT04075981)
- Testing
- Botulinum Toxin Type A Injection [Xeomin]
- Where
- 7 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation, Inflammatory Marker
Red Cell Distribution Width as a Predictor for Post Operative Atrial Fibrillation After Open Heart Surgries
In this study we investigate the correlation between RDW and POAF, as we use the RDW as a predictor for inflammation for prediction of POAF
- Conditions
- Atrial Fibrillation, Inflammatory Marker, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT06286111
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Coronary Artery Disease, Atrial Fibrillation New Onset
Effect of Left Posterior Pericardiotomy for the Prevention of POAF
This study is planned to evaluate the effect of left posterior pericardiotomy for the prevention of postoperative atrial fibrillation after coronary artery bypass grafting.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation New Onset, Pericardial Effusion
- Trial name
- ELIMINATE-AF (NCT06159985)
- Testing
- left posterior pericardiostomy
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Seoul National University Hospital
Post-Operative Atrial Fibrillation
Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Adult Participants Undergoing Open-chest Cardiac Surgery (NOVA)
This was a multi-center, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study to evaluate the efficacy and safety of botulinum toxin type A (AGN-151607) injections into the epicardial fat pads, foci of…
- Trial name
- NCT03779841
- Testing
- AGN-151607
- Where
- 32 sites in United States, Austria and 7 more
- Volunteers
- 323 people
- Sponsor
- AbbVie
Atrial Fibrillation (AF), Cardiac Events
Prevention of Atrial Fibrillation After Cardiac Surgery by Pericardiotomy
PRINCE-CH is a multicentre, randomized controlled trial which evaluates the effectiveness and safety of posterior pericardiotomy in preventing POAF after cardiac surgery in Chinese population.
- Conditions
- Atrial Fibrillation (AF), Cardiac Events, Pericardial Effusion
- Trial name
- PRINCE-CH (NCT06728826)
- Testing
- Posterior pericardiotomy
- Where
- China
- Volunteers
- 650 people
- Sponsor
- Changhai Hospital
Atrial Fibrillation
Safety and Efficacy Study of Amniotic Membrane Patch to Treat Postoperative Atrial Fibrillation
The purpose of this study is to to evaluate the rate of new onset postoperative atrial fibrillation in subjects receiving the amniotic membrane patch placed on the epicardial surface as compared to subjects who did not undergo…
- Trial name
- NCT02193321
- Testing
- Amniotic Membrane Patch
- Where
- United States
- Sponsor
- University of Arizona
Atrial Fibrillation (AF), Catheter Ablation
PROMBot-HSM-FA: Protocol for a Feasibility Study of a Chatbot Platform to Collect Patient-reported Outcomes After AF Ablation
The goal of this clinical trial is to learn if using a WhatsApp-based chatbot called PROMBot-FA can help people recover after atrial fibrillation ablation.
- Trial name
- PROMBot-HSM-FA (NCT07237178)
- Testing
- PROMBot-FA Chatbot-Supported Follow-Up, Standard Care (in control arm)
- Volunteers
- 76 people
- Sponsor
- Ana Rita Londral, PhD
CABG, Visceral Adipose Tissue
Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After CABG
Obesity has become a major public health problem in both developed and developing countries, with a continuous increase particularly since the 1980s.
- Conditions
- CABG, Visceral Adipose Tissue, Atrial Fibrillation (AF)
- Trial name
- NCT07467941
- Testing
- Postoperative AF Group, Non-AF Group
- Volunteers
- 300 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Atrial Fibrillation, Lung Cancer
Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection
Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the…
- Trial name
- NCT00300495
- Testing
- Amiodarone, Control arm, standard care
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Atrial Fibrillation
Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
The purpose of this study is to compare the therapeutic strategies of rate control versus rhythm control in cardiac surgery patients who develop in-hospital postoperative atrial fibrillation or atrial flutter (AF).
- Trial name
- NCT02132767
- Testing
- Amiodarone, DC-cardioversion, Rate Control
- Where
- 23 sites in United States, Canada
- Volunteers
- 523 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atrial Fibrillation
Treatment of Postoperative Atrial Fibrillation - Comparison of Amiodarone and Placebo.
Post-operative atrial fibrillation (POAF) is the most common complication encountered after cardiac surgery; reports show POAF to occur in ~ 35% of patients after CABG.
- Trial name
- NCT02715687
- Testing
- Amiodarone
- Volunteers
- 400 people
- Sponsor
- Rambam Health Care Campus
Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial
Post-operative atrial fibrillation after coronary artery bypass grafting (CABG)
- Trial name
- NCT07611019
- Testing
- Colchicine 0.5 MG oral tablet twice daily
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Coronary Artery Bypass
A Retrospective Analysis of the Predictive Potential of Pre-operative
Roughly thirty percent of people that undergo open heart surgery get an abnormal heart beat afterwards known as atrial fibrillation (AF).
- Trial name
- NCT00321282
- Testing
- Atrial Fibrillation
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Colchicine Adverse Reaction, Atrial Fibrillation New Onset
COlchicine in Cardiac Surgery
Postoperative atrial fibrillation (POAF) is a major complication of cardiac surgery, which could lead to high morbidity and mortality, increase duration of hospital stay and increase the cost of treatment.
- Trial name
- COCS (NCT04224545)
- Testing
- Colchicine Pill
- Where
- 2 sites in Russia
- Volunteers
- 267 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Atrial Fibrillation, Atrial Arrhythmia
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
- Trial name
- NCT05014802
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Atrial Fibrillation
Post-operative Corticosteroid Treatment After Mitral Valve Surgery
The aim of the study is to intestigate whether three days intravenous corticosteroid management prevent atrial fibrillations in adults after mitral valve surgery.
- Trial name
- MitralPOCS (NCT03682393)
- Testing
- Hydrocortisone
- Where
- Finland
- Sponsor
- Kuopio University Hospital
Coronary Artery Bypass
Atorvastatin for Prevention of Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting Surgery
The purpose of this study is to determine whether pretreatment with atorvastatin protects against atrial fibrillation following off-pump coronary artery bypass graft surgery.
- Trial name
- NCT00611143
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Postoperative Atrial Fibrillation
Effect of Alpha-Lipoic Acid Supplementation on the Incidence of Postoperative Atrial Fibrillation in Cardiac Surgery Patients
ALA is administered orally since it is without difficulty absorbed in the stomach. ALA goes through the blood brain barrier and does not show toxic effects and actions at doses used for prophylactic and therapeutic purposes.
- Trial name
- NCT06151652
- Testing
- Alpha Lipoic Acid 600 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 350 people
- Sponsor
- Ain Shams University
Postoperative Atrial Fibrillation, Strains
Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The incidence of postoperative atrial fibrillation (POAF) after cardiac surgery is around 30%. POAF increases the risk of developing permanent atrial fibrillation and raises the risk of cardiac decompensation, stroke, acute…
- Trial name
- ODFAPO (NCT06054360)
- Where
- France
- Volunteers
- 334 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens