Clinical trials: Postnatal Depression
Childbirth Problems, Perinatal Depression
Daring Birth - Digital Coaching Solution to Improve Childbirth Experience
The aim of the study is to investigate the effectiveness of the Daring Birth digital coaching solution (the Natal Mind app) in enhancing the experience of childbirth.
- Conditions
- Childbirth Problems, Perinatal Depression, Anxiety in Pregnancy, Pregnancy Related
- Trial name
- NCT06585839
- Testing
- Digital coaching solution to improve childbirth experience, Application for the control group
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aalto University
Mental Health Wellness, Emotional Problem
Behaviours and Emotions in Preschoolers
In this TARGet Kids! Study, we want to find out whether a short questionnaire can be used to help find out about mental health problems in preschool age children.
- Conditions
- Mental Health Wellness, Emotional Problem, Behavioural Problem, Post Partum Depression
- Trial name
- BeEPS (NCT03856931)
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- TARGetKids!
Post Partum Depression
Improving Outcomes for Low-Income Mothers With Depression
This is a randomized comparative effectiveness trial to improve outcomes among pregnant and post-partum women with symptoms of depression.
- Trial name
- NCT03221556
- Testing
- Engagement-Focused Care Coordination (EFCC), Problem Solving Education (PSE)
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- Boston Medical Center
Post-partum Depression
PreParent: Internet-based Digital Tools to Screen for and Prevent Postpartum Depression in Parents-to-be
The goal of this randomized controlled study is to evaluate whether an online intervention that combines psychoeducation and affective cognitive training can help prevent postpartum depression in pregnant women and co-parents who…
- Trial name
- NCT07302165
- Testing
- Online prenatal affective cognitive training
- Where
- Denmark
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Postpartum Depression
Dynamic Neural Mechanisms of Brexanolone-induced Antidepressant Effects in Postpartum Depression
This is a feasibility study of performing repeated EEG recordings and assessment of affective states during open-label administration of BRX to women with postpartum depression.
- Trial name
- BRX-PPD (NCT05543746)
- Testing
- Brexanolone
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Breastfeeding, Exclusive, Fatigue
MBSR and NLP, Postpartum Breastfeeding and Depression
The postnatal period is a risky period in which mothers experience regressive and progressive changes and rapid biopsychosocial changes.
- Conditions
- Breastfeeding, Exclusive, Fatigue, Sleep, Postpartum Depression
- Trial name
- postpartum (NCT06628986)
- Testing
- MBSR, NLP, control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aysegul Kilicli
Mother-child Relationship Disturbances
Mother-Infant Psychoanalysis Project of Stockholm (MIPPS)- Follow-up at 4½ Years
An RCT comparing mother-infant psychoanalytic treatment (MIP) with Child Health Centre care in cases of mother-infant relationship disturbances was performed on 80 cases in Stockholm 2005-2008.
- Trial name
- MIPPS-02 (NCT01087112)
- Testing
- Mother-Infant Psychoanalytic tmt, Child Health Centre care
- Where
- Sweden
- Volunteers
- 71 people
- Sponsor
- Karolinska Institutet
Depressive Disorder, Major, Postpartum Depression
Mommy-Baby Treatment for Perinatal Depression
Perinatal depression is a major public health problem, affecting 15% of women during pregnancy through the postpartum period, with adverse consequences for the mother, the fetus, the infant, and the family.
- Trial name
- NCT01744041
- Testing
- Dyadic Interpersonal Psychotherapy, Enhanced Treatment as Usual
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Pregnancy Related, Pregnancy Complications
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Perinatal Mood and Anxiety Disorders (PMADs) encompass a range of mental health disorders that occur during pregnancy and up to one year postpartum. Approximately 13% of women experience PMADs.
- Conditions
- Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression
- Trial name
- RISE (NCT05552053)
- Testing
- MWSH plus Candlelit Care, MWSH
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postnatal Depression
Postnatal Depression, Attachment and Self-defining Memories
The specificity of postnatal depression (PND) was acted as full entity within the depressions, by B. Pitt in 1968, through the description of a specific nosography which describes "an atypical depression of the post-partum ".
- Trial name
- PNDattachMEMO (NCT03346551)
- Testing
- Evaluation of the quality attachment : "Adult Attachment Narratives" and "CaMir scale", Evaluation of the self-defining memories : "Specific Questionnaire during an interview"
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Postpartum Depression, Postpartum Anxiety
A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting Program
Experiencing postpartum mood and/or anxiety disorders (like postpartum depression; PMADs) can make parenting challenging, but group therapy may help both these parents and their babies.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Parenting Stress, Parent Child Relationships
- Trial name
- PMAD-CARE (NCT06042166)
- Testing
- Connecting and Reflecting Experience (CARE) Program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Montefiore Medical Center
Insomnia, Post Partum Depression
Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression
The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms.
- Trial name
- PPD (NCT03596879)
- Testing
- dCBTI, Sleep Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Henry Ford Health System
Post Partum Depression
Effectiveness of Mat Pilates and Aerobic Training on Fatigue and Depression
The aim is to see fatigue and depression levels in postpartum females and to evaluate ho two well-known exercises, Mat Pilates and Aerobic training can help to reduce the fatigue levels in postpartum females
- Trial name
- NCT04813341
- Testing
- Pilates training, Aerobic Training
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Anxiety, Postnatal Depression
Transdiagnostic Internet Cognitive-behavior Therapy for Mixed Anxiety and Depressive Symptoms in Postnatal Women
This research project aims to examine the acceptability and efficacy of a French-Canadian adaptation of a postnatal anxiety and depression program.
- Trial name
- postnataIiCBT (NCT06778096)
- Testing
- Postnatal anxiety and depression iCBTprogram
- Where
- 4 sites in Canada
- Volunteers
- 226 people
- Sponsor
- Université de Sherbrooke
Postpartum Depression, Sleep Disorder
The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression
It is recommended by the American College of Obstetricians and Gynecologists' Committee on Obstetric Practice that all obstetricians screen each women for postpartum depression and anxiety with a validated instrument.
- Conditions
- Postpartum Depression, Sleep Disorder, Breast Feeding, Self Esteem
- Trial name
- NCT03763435
- Testing
- Antenatal pregnancy classes
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Bartin State Hospital
Postpartum Depression (PPD), Pregnancy
Clinical Validation of a Predictive Test for Postpartum Depression
The goal of this observational study is to develop a blood test that may be predictive of postpartum depression. This Blood test is investigational and not yet FDA approved.
- Trial name
- PREVAIL (NCT06831968)
- Testing
- Enlighten
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Postpartum Depression, Heart Rate Variability
Vitamin B6 and Depression in Pregnant and Peri-partum Women
Perinatal depression is a highly prevalent and serious health issue during pregnancy. According to statistics, approximately one out of every ten postpartum women experiences this condition.
- Trial name
- NCT06445933
- Testing
- Vitamin B6
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postpartum Depression
A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression
The primary purpose of this study was to determine if treatment with SAGE-217 reduces depressive symptoms in participants with severe postpartum depression (PPD) compared to placebo as assessed by the change from baseline in the…
- Trial name
- NCT02978326
- Testing
- SAGE-217 15/20 mg Oral Solution, SAGE 217 30 mg Capsules
- Where
- 27 sites in United States
- Volunteers
- 276 people
- Sponsor
- Biogen
Post-partum Depression
Pilot Study on the Use of Acupuncture for Postpartum Depression
The proposed study is a randomized controlled trial to examine the efficacy and safety of active acupuncture versus placebo acupuncture for the treatment of postpartum depression.
- Trial name
- NCT01178008
- Testing
- Active acupuncture
- Where
- 3 sites in Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Postpartum Depression
Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of Trazodone
Postpartum depression is a serious illness that affects approximately 17% of women who have recently given birth. Untreated depression appears to have negative effects for both the mother and her baby.
- Trial name
- NCT05299398
- Testing
- Trazodone
- Where
- Canada
- Sponsor
- Verinder Sharma