Clinical trials: Postmenopause
Menopause
Relationship Between Genitourinary and Respiratory Symptoms in Postmanopause
The aim of this study is to evaluate the relationship between genitourinary system symptoms and respiratory function and respiratory muscle strength in postmenopausal women.
- Trial name
- NCT07651566
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Halic University
Postmenopause, Breast Cancer
A Treatment With Fulvestrant and Exemestane in Postmenopausal Patients With Advanced Hormone Receptor-Positive (HR) + Breast Cancer
For patients receiving Faslodex 500 mg, to compare the effectiveness in terms of Time to Progression (TTP) as a function of the line of treatment (i.e. 1st vs. 2nd vs. 3rd line).
- Trial name
- ACT-FASTER: (NCT01171417)
- Where
- 92 sites in Germany
- Volunteers
- 570 people
- Sponsor
- AstraZeneca
Vaginal Atrophy
Study Evaluating Bazedoxifene/Conjugated Estrogen Combinations in Vasomotor Symptoms Associated With Menopause
The purpose of this study is to determine whether Bazedoxifine/conjugated estrogens are effective in the treatment of vaginal atrophy.
- Trial name
- NCT00238732
- Testing
- Bazedoxifene/Conjugated Estrogen
- Where
- 63 sites in United States
- Volunteers
- 650 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Osteoporosis, Fall Patients
Relationships Among Body Mass Index, Body Balance and Bone Mineral Density in Postmenopausal Women
Body composition, bone mineral density (BMD), and body balance are important factors that threaten postural control. They act as vital elements in the vicious circle that leads to fracture occurrence in elderly population…
- Conditions
- Osteoporosis, Fall Patients, Postmenopausal Disorder
- Trial name
- NCT03280693
- Testing
- Diagnostic test
- Volunteers
- 48 people
- Sponsor
- Cairo University
Stress Urinary Incontinence in Women
Perineal Ultrasound, Post-Void Residual, and Lower-Limb Alignment in Stress Incontinence
Stress urinary incontinence (SUI) in postmenopausal women is traditionally considered a local pelvic floor disorder, but emerging evidence suggests that spinopelvic and lower limb alignment may also contribute to continence…
- Trial name
- NCT07747727
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Postmenopausal Osteoporosis, Postmenopause
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world.
- Conditions
- Postmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis D
- Trial name
- NCT05347082
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital Regional 1o de Octubre
Hearing Loss, Osteoporosis, Postmenopausal
Hearing Loss and Osteoporosis
To compare the audiological profiles in postmenopausal women with and without osteoporosis and to examine the pattern of hearing loss in osteoporotic patients.
- Trial name
- NCT03895333
- Testing
- Audiological profiling and bone mineral densitometry measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Obesity (BMI Equal to or >30), Postmenopausal Symptoms
Time-Restricted Eating and Personalized Energy-Restricted Diet in Obese Postmenopausal Women
This clinical study aims to compare the effects of time-restricted eating and a personalized energy-restricted diet on anthropometric measurements, body composition, biochemical parameters, blood pressure, handgrip strength…
- Conditions
- Obesity (BMI Equal to or >30), Postmenopausal Symptoms, Sleep Quality
- Trial name
- NCT07874399
- Testing
- Time-Restricted Eating, Personalized Energy-Restricted Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Hot Flashes
Amino Acid Therapy for Hot Flashes in Postmenopausal Women
The purpose of this study is to determine the safety, tolerability, and effectiveness of the amino acid L-isoleucine in the treatment of hot flashes in postmenopausal women.
- Trial name
- NCT00081952
- Testing
- L-norleucine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Breast Cancer
Exemestane With Celecoxib as Neoadjuvant Treatment in Postmenopausal Women With Stage II, III, and IV Breast Cancer
To test whether the addition of the COX-2 inhibitor, celecoxib, will decrease the gene expression of CYP19 in breast cancers collected from postmenopausal women that receive neoadjuvant exemestane.
- Trial name
- NCT00201773
- Testing
- Exemestane, Celecoxib, Correlative studies
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Sleep Disturbance
Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints
This open-label study was designed to evaluate whether a daily dietary sleep supplement could improve sleep quality and related daytime well-being in menopausal women aged 40 to 65 with sleep complaints.
- Trial name
- NCT07839312
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Osteoporosis
Study Evaluating Bazedoxifene Acetate In Osteoporosis In Postmenopausal Women
The purpose of this study is to determine whether bazedoxifene acetate is safe and effective in the treatment of osteoporosis in postmenopausal women.
- Trial name
- NCT00205777
- Testing
- Bazedoxifene Acetate
- Where
- 375 sites in United States, Argentina and 28 more
- Volunteers
- 7,609 people
- Sponsor
- Pfizer
Menopause
Estrogen and the Urogenital Microbiome in GSM
This is a study of how local estrogen treatment affects the microbiome of the vagina and bladder in postmenopausal women experiencing symptoms as part of "Genitourinary Syndrome of Menopause." The goal is to understand more about…
- Trial name
- NCT03336437
- Testing
- Estradiol vaginal ring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Menopause
Symptom Management Program Based on Story Theory for Postmenopausal Women (SEMSTOP)
Purpose: To investigate the effect of the Symptom Management Program Based on Story Theory on vasomotor symptoms and sleep quality in postmenopausal women.
- Trial name
- SEMSTOP (NCT05697133)
- Testing
- SEMSTOP, control
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Female Sexual Dysfunction
Effectiveness of Testosterone Undecanoate to Improve Sexual Function in Postmenopausal Women
Additional testosterone undecanoate can improve female sexual function in postmenopausal women which one aspects of quality of life.
- Trial name
- NCT01724658
- Testing
- Testosterone undecanoate
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Bioequivalance, Post-menopause
An Open-label, Randomized, Single-dose, Two-treatment, Four-period, Fully Replicate Crossover Bioequivalence Study in Healthy Female Adult Participants Under Fasting Conditions Comparing the Test Product, Prontogest Solution for IM Injection With the Reference Product, Progesterone Injection
Bioequivalence study of two injectable formulation of progesterone in healthy post-menopausal women
- Trial name
- Prontogest (NCT07495007)
- Testing
- Progesterone IM of 100 mg
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Zi Diligence Biocenter
Angina, Unstable, Cardiovascular Diseases
Postmenopausal Hormone Therapy in Unstable Angina
To determine if estrogen therapy in postmenopausal women with unstable angina reduces the incidence of ischemic episodes.
- Conditions
- Angina, Unstable, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000601
- Testing
- estrogen replacement therapy, estrogens, progesterone
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Menopause
TRANSDERMAL HRT RELIEVING POSTMENOPAUSAL SYMPTOMS
There is a dilemma and a permanent debate about side effects on drugs administered orally. The first-pass metabolism is related with many side effects, since the metabolites of these compounds affect the course of human…
- Trial name
- THRT (NCT02033512)
- Testing
- Transdermal Hormone Replacement Therapy, Transdermal Nanoformulation, Transdermal formulation
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Healthy
A Food Effect Study With ZN-c5 in Healthy Post-Menopausal Subjects
This is a single-center, randomized, open-label, two-period, 2-way crossover food effect study to determine the comparative bioavailability of ZN-c5 under fed and fasting conditions, following single-dose administration of ZN-c5…
- Trial name
- NCT04561752
- Testing
- ZN-c5
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zeno Alpha Inc.
Cardiovascular Diseases, Heart Diseases
Myocardial Infarction and Non-contraceptive Estrogen Use
To evaluate whether the use of noncontraceptive estrogen influenced the incidence of first myocardial infarction in women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Menopause
- Trial name
- NCT00005185
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)