Clinical trials: Postmenopausal Period
Healthy Female Participants, Postmenopause
A Study to Assess the Bioavailability and Adhesion of Estradiol/Levonorgestrel TDS in Healthy Post-Menopausal Female Participants
The purpose of this study is to compare the bioequivalence and adhesion performance of a test estradiol/levonorgestrel transdermal delivery system (TDS) with the reference product, Climara Pro® (estradiol/levonorgestrel…
- Trial name
- NCT07851649
- Testing
- Test Estradiol/Levonorgestrel Transdermal Delivery System, Climara Pro® (Estradiol/Levonorgestrel Transdermal System)
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.
Postmenopausal Osteoporosis, Postmenopause
Study Comparing Bioequivalence of Two New Formulations of Premarin/MPA With Premarin/MPA Reference Formulation.
This study will compare the bioequivalence of two new investigational combination formulations of Premarin and medroxyprogesterone acetate (MPA) with a currently marketed formulation of Premarin and medroxyprogesterone, Prempro™.
- Trial name
- NCT00381251
- Testing
- Formulations A and B of Premarin/MPA 0.45 mg/0.5 mg and PREMPRO0.45 mg/0.5 mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Visceral Obesity, Non-alcoholic Fatty Liver
Effect of Multi-ingredient on Visceral Adiposity & Non-alcoholic Fatty Liver Disease in Postmenopausal Women With Abdominal Obesity
This study aims to evaluate the effect of daily intake of a specific combination of different natural histidine-related amino acids in combination with dietary recommendations, in the reduction of visceral fat, as well as their…
- Conditions
- Visceral Obesity, Non-alcoholic Fatty Liver, Postmenopausal
- Trial name
- FATHIS+ (NCT06377631)
- Testing
- Multi-ingredient of L-histidine, L-serine, L-carnosine and N-Acetylcysteine
- Where
- 2 sites in Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Cardiometabolic Diseases, Postmenopause
Exercise and Prolonged Fasting to Improve Brown Adipose Tissue Function in Postmenopausal Women
Type of Study: Clinical Trial Goal: The goal of this clinical trial is to investigate mitochondrial function in interscapular brown adipose tissue (iBAT) in postmenopausal women and determine whether aerobic exercise, prolonged…
- Trial name
- EMPOWER-BAT (NCT07837752)
- Testing
- Aerobic exercise, Prolonged fasting
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Hypercholesterolemia, Postmenopause
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
Estrogen therapy has been associated with reduced risk of coronary heart disease events in observational studies of postmenopausal women.
- Trial name
- NCT00001752
- Testing
- L-arginine, Estrogen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Women, Community Health Workers
Supplying Useful Perimenopause Through Post-menopause Online Resources and Tools
The goal of the study is to examine the extent to which exposure to the SUPPORT prototype increases community health workers' (CHWs) knowledge, skills, and self-efficacy to conduct effective outreach to minority women…
- Conditions
- Women, Community Health Workers, Health, Menopause
- Trial name
- SUPPORT (NCT07589335)
- Testing
- Lessons 1-4 for SUPPORT course
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- KDH Research & Communication
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Exercise Training in Older Diabetic Women
Type 2 diabetics (non-insulin-dependent) are more than five times as likely to suffer an initial myocardial infarction (MI; heart attack) compared to nondiabetics.Female diabetics in particular, have a higher mortality rate for…
- Trial name
- NCT00341614
- Testing
- 3-month Exercise Training and Diet Education
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of San Francisco
Metabolic Syndrome, Protection Against, Menopause
Diet, Cardiometabolic Risk (CM) and Menopause Symptoms
This research will explore the question 'What impact do the Mediterranean Diet (MedDiet) and the Heart UK Ultimate Cholesterol Lowering Plan (UCLP) Menopause have on cardiometabolic risk factors and the frequency and severity of…
- Trial name
- NCT05764473
- Testing
- The impact of MedDiet on cardiometabolic risk factors and menopause symptoms, The impact of UCLP on cardiometabolic risk factors and menopause symptoms
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Healthy Volunteers
Effect of Calcium 500 mg and Vitamin D3 1000 IU Chewable Tablet on Intestinal Calcium Absorption
The purpose of this study is to demonstrate that the intestinal absorption of calcium from a novel calcium carbonate-vitamin D3 chewable tablet formulation (calcium 500 milligrams (mg) and vitamin D3 1000 International Units…
- Trial name
- NCT02338713
- Testing
- Calcichew D3, Noncarbonated Water
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Takeda
Calcium Deficiency, Vitamin D Deficiency
Human Pharmacology Trial of Calcium-vitamin D3 Tablet in Healthy Participants
The purpose of this study is to demonstrate that the intestinal absorption of calcium from a newly developed calcium carbonate-vitamin D3 chewable tablet formulation increases the amount of calcium excreted in urine and decreases…
- Trial name
- Osteopro (NCT01639222)
- Testing
- Calcium 500 mg and Vitamin D3 800 IU, Low calcium meals
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Takeda
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Sexual Dysfunction, Postmenopausal Symptoms
Examination of the Effects of Pelvic Floor Exercises on Vaginal and Sexual Health in Postmenopausal Women.
The purpose of this study; To investigate the effects of pelvic floor muscle exercises on vaginal and sexual health in postmenopausal women.
- Conditions
- Sexual Dysfunction, Postmenopausal Symptoms, Pelvic Floor Muscle Weakness
- Trial name
- NCT06294197
- Testing
- Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hatice Gulsah Kurne
Postmenopause
Study Evaluating Bazedoxifene/CE in Postmenopausal Women
The purpose of this clinical trial is to study the blood levels of a drug (conjugated estrogens) in the body from one dosage form compared to another.
- Trial name
- NCT00550433
- Testing
- Bazedoxifene/Conjugated Estrogens
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01044563
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Menopause, Postmenopause
Midlife Cholesterol Study
The postmenopausal state is associated with an increase risk for heart disease. Much of this increase in risk may be due to the loss of estrogen (the main female hormone) and the effect of this loss on lipids (blood fats).
- Conditions
- Menopause, Postmenopause, Premenopause, Cardiovascular Disease
- Trial name
- NCT00361075
- Testing
- transdermal estradiol patch (Vivelle), oral estrogen (Estrace), progesterone (Prometrium)
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Menopause
TRANSDERMAL HRT RELIEVING POSTMENOPAUSAL SYMPTOMS
There is a dilemma and a permanent debate about side effects on drugs administered orally. The first-pass metabolism is related with many side effects, since the metabolites of these compounds affect the course of human…
- Trial name
- THRT (NCT02033512)
- Testing
- Transdermal Hormone Replacement Therapy, Transdermal Nanoformulation, Transdermal formulation
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Atherosclerosis, Postmenopause
EPAT: Estrogen in the Prevention of Atherosclerosis Trial
The purpose of this study is to determine the effects of estrogen replacement therapy (ERT) on the progression of early atherosclerosis in healthy postmenopausal women without preexisting cardiovascular disease (CVD).
- Trial name
- NCT00115024
- Testing
- Micronized 17B-estradiol
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Atherosclerosis
Study of Anti-atherosclerotic Activity of Karinat in Postmenopausal Women
The purpose of this study is to investigate the anti-atherosclerotic action of natural drug Karinat based on phytoestrogen-rich botanicals in postmenopausal women.
- Trial name
- PEARS-POST (NCT01742000)
- Testing
- Karinat
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institute for Atherosclerosis Research, Russia
Post Menopausal Women
The Role of Diet Quality in Sleep Among Women in Postmenopause
This single-center, randomized controlled trial with parallel groups, consists of an intensive nutritional intervention based on a high-fiber Mediterranean diet (target intake: 30-35 g/day of dietary fiber), which will be…
- Trial name
- EMILE (NCT07918287)
- Testing
- Intensive High-Fiber Mediterranean Diet Counseling, Low-Intensity Mediterranean Diet Counseling
- Where
- Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Barcelona