Clinical trials: Post-operative Antibiotics
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Surgical Site Infection, Complication of Surgical Procedure
Topical Antibiotics in Surgical Site
Ankle fractures are one of the most common injuries in traumatology. It is the fourth most common fracture in general population after hip, wrist, and hand fractures.
- Trial name
- NCT05363462
- Testing
- Vancomycin 1000 MG
- Where
- Mexico
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Surgical Site Infection, Surgical Complication
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.
- Conditions
- Surgical Site Infection, Surgical Complication, Gynecologic Cancer
- Trial name
- NCT05210556
- Testing
- Diagnosed with Surgical Site Infection
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Endodontically Treated Teeth, Postoperative Pain
Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitations, and Oral Health-related Quality of Life
Objective: The objective of this study will be to evaluate the effectiveness of different endodontic treatment techniques in postoperative symptoms, apical repair, longevity of rehabilitations, and oral health-related quality of…
- Conditions
- Endodontically Treated Teeth, Postoperative Pain, Edema, Photochemotherapy
- Trial name
- NCT03704857
- Testing
- Foraminal Enlargement / Irrigating solutions / Filling materials, Photobiomodulation, Passive ultrasonic irrigation
- Where
- Brazil
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Pulp Necrosis
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1.
- Trial name
- NCT03763110
- Testing
- Photo Activated Disinfection, antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontic Disease
Evaluation of Antimicrobial Efficacy and Postoperative Pain After Using Silver Nanoparticles and Chitosan Nanoparticles Against Enterococcus Faecalis and Candida Albicans Biofilm
Silver nanoparticles possess unique physicochemical and biological properties in addition to their antibacterial capabilities. Similarly, zinc oxide nanoparticles have demonstrated antibacterial effects against a wide range of…
- Trial name
- NCT06172023
- Testing
- Silver Nanoparticles Irrigant, Chitosan Nanoparticles Irrigant
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Minia University
Salivary Duct
Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement
Salivary duct stent placement is a common practice to maintain duct patency after salivary duct repair or interventional sialoendoscopy; procedures performed to manage salivary duct pathology such as stenosis, traumatic injury or…
- Trial name
- NCT03333408
- Testing
- Postoperative Oral Antibiotics (Clindamycin or Augmentin)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Supracondylar Humerus Fracture, Infection
Supracondylar Pinning Antibiotic Stewardship (SPAS) Trial
Prospective, multi-center, randomized controlled trial studying infection rate with or without prophylactic antibiotics at the time of closed reduction and percutaneous pinning of pediatric supracondylar humerus fractures.
- Trial name
- SPAS (NCT04288206)
- Testing
- Cefazolin, normal saline
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Legacy Health System
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Surgical Site Infection
Antibiotics for Prevention of SSI in Obese Women Undergoing CS
Effect of cephalexin plus metronidazole on SSI better than cephalexin alone in obese women undergoing CS
- Trial name
- NCT03736187
- Testing
- Cephalexin
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infection, Surgical Site
Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study
Patients randomly aligned in 2 groups.Vicryl plus sutures were used in group 1 for closing subperiostal flaps after dental implant surgeries and vicryl sutures were used in group 2.
- Trial name
- NCT03659344
- Testing
- Vicryl plus
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Postoperative Pain
Assessment of Pain and Antibacterial Activity of Chitosan Versus Sodium Hypochlorite as Irrigant in Infected Canal
A randomized clinical trial that aims to study the effect of chitosan nanoparticles (CS-np) versus sodium hypochlorite as a root canal irrigant on postoperative pain and antibacterial activity against E.faecalis in infected root…
- Trial name
- NCT03719261
- Testing
- chitosan nanoparticles, Sodium Hypochlorite
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Impacted Wisdom Tooth
Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin
The aim of this study was investigate the comparison of postoperative effects of local antibiotics mixed with platelet-rich fibrin and postoperative systemic antibiotic applications prescribed for mandibular impacted third molar…
- Trial name
- NCT04989127
- Testing
- Diagnosis, traditional osteotomies, Platelet Rich Fibrin
- Where
- Cyprus
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Perforated Appendicitis, Postoperative Infection
Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis
After appendix has been removed for perforated appendicitis, patients will receive postoperative antibiotics. In the last 5 years, the literature has transitioned from a 3 -drug therapy to 2-drug therapy.
- Trial name
- NCT03289351
- Testing
- Piperacillin, Tazobactam Drug Combination
- Where
- 2 sites in United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Site Infection
Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances
Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative…
- Trial name
- NCT04218110
- Testing
- Isopropyl alcohol & Chlorhexidine Gluconate Antiseptic, Prevantics 3.15 % / 70 % Swabstick
- Where
- Romania
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Surgical Site Infection, Antibiotic Prophylaxis
The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.
This study will seek to describe current practice of antibiotic prophylaxis to identify the effect of appropriate perioperative antimicrobial coverage - specifically regarding timing, dose adjustments, and redosing - on surgical…
- Trial name
- NCT03982810
- Testing
- Antibiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Bacterial Reduction on Skin Flora Post-product Application
In-vivo Efficacy Study of Patient Pre-operative Preps
The purpose of this study is to determine the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT01968707
- Testing
- ChloraPrep Hi-Lite Orange, Normal saline, 3M CHG/IPA Prep Tint 10.5-mL
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Postoperative Infection
Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery
Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation.
- Trial name
- NCT06177444
- Testing
- Antibiotic
- Where
- Denmark
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Irreversible Pulpitis, Caries,Dental
Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth
The aim of the study is to evaluate effectiveness of cinnamon extract versus sodium hypochlorite as root canal irrigant for in pulpectomy of primary teeth in reduction of bacterial count .
- Trial name
- NCT05860712
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University