Clinical trials: Post-Traumatic Stress Disorder
PTSD, Sleep Disturbance
Electrical Vestibular Nerve Stimulation (VeNS) as a Method of Sleep Management in People With PTSD
This double blind randomized controlled study will enroll 20 subjects and will be conducted remotely. The study will be randomized for an 8-week period with a 1:1 active to sham device allocation.
- Conditions
- PTSD, Sleep Disturbance, Insomnia
- Trial name
- NCT04780893
- Testing
- Modius Sleep
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Post-Traumatic Stress Disorder
Phase II Study of BNC210 in PTSD
This is a randomized, double-blind, placebo-controlled study, evaluating the effects of BNC210 versus placebo on the symptoms of Post-Traumatic Stress Disorder, as measured by the Clinician-Administered PTSD Scale for DSM-5…
- Trial name
- RESTORE (NCT02933606)
- Testing
- BNC210
- Where
- 25 sites in United States, Australia
- Volunteers
- 193 people
- Sponsor
- Bionomics Limited
Post Traumatic Stress Disorder
Exploring Clinical Study Experiences of People With Post Traumatic Stress Disorder
Participation in post traumatic stress disorder observational study serves as a crucial contribution to advancing medical knowledge and refining the care provided to individuals facing similar health challenges.
- Trial name
- NCT06146049
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Posttraumatic Stress Disorder
Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD
The purpose of this clinical trial is to learn if MDMA-assisted therapy is safe and effective in people with PTSD. The main question it aims to answer is: Do two open-label sessions of MDMA-assisted therapy reduce PTSD symptoms?…
- Trial name
- NUMCAP1 (NCT04968938)
- Testing
- midomafetamine, Therapy
- Sponsor
- Resilient Pharmaceuticals
Stress Disorders, Post-Traumatic
Trial to Evaluate Efficacy of Magnetic Resonant Therapy (MRT) in PTSD
The purpose of this study is to establish the efficacy of Magnetic Resonant Therapy in treating Post Traumatic Stress Disorder in Veterans.
- Trial name
- NCT02268084
- Testing
- Magnetic EEG/ECG-guided Resonance Therapy
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Wave Neuroscience
Post Traumatic Stress Disorder
A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects
This is an open-label, single, ascending dose study evaluating the PK and safety of methylone in healthy subjects.
- Trial name
- NCT06303648
- Testing
- Methylone
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcend Therapeutics
Stress Disorders, Post-Traumatic
EEG Personalized Transcranial Magnetic Stimulation (eTMS) for Post-Traumatic Stress Disorder
This is an open-label safety pilot study of the Electroencephalogram (EEG) Transcranial Magnetic Stimulation (eTMS) treatment for Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT06081309
- Testing
- EEG-based personalized TMS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wave Neuroscience
Stress Disorders, Post-Traumatic, Combat Disorders
NightWare Randomized Trial 02
This study will provide preliminary estimates of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare
- Trial name
- TNT/NW (NCT04040387)
- Testing
- NightWare Therapeutic System
- Where
- 4 sites in United States
- Volunteers
- 270 people
- Sponsor
- NightWare
PTSD, Post Traumatic Stress Disorder PTSD
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
The goal of this clinical trial is to evaluate the safety and effectiveness of the gammaCore non-invasive vagus nerve stimulation (nVNS) device as an additional treatment for symptoms of post-traumatic stress disorder (PTSD) in…
- Conditions
- PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT07523685
- Testing
- non-invasive vagus nerve stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Acacia Clinics
Post Traumatic Stress Disorder
An Evaluation of the Long-term Efficacy and Safety of Methylone for the Treatment of PTSD
This is an extension study of participants who previously completed a Transcend-sponsored clinical trial evaluating TSND-201 as a treatment for PTSD. Participants will be followed for up to 52 weeks.
- Trial name
- IMPACT-EXT (NCT06237426)
- Testing
- Methylone
- Where
- 9 sites in United States, Ireland and 1 more
- Volunteers
- 44 people
- Sponsor
- Transcend Therapeutics
PTSD, Post Traumatic Stress Disorder
Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms
This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.
- Trial name
- NCT07316088
- Testing
- OTX-601 Digital Therapeutic, OTX-003 Comparator app
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oui Therapeutics, Inc.
PTSD - Post Traumatic Stress Disorder
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to…
- Trial name
- NCT07280065
- Testing
- Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
- Where
- 6 sites in United States, Australia
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
COVID-19
Assessment of Mental Health in Healthcare Workers Exposed to COVID-19 Patients
The recent COVID-19 outbreak has put the health care workers on the frontline to interact and provide support to the patients. Based on previous disease outbreak-associated studies, it is evident that these individuals are at a…
- Trial name
- BADS-PTSD (NCT04473118)
- Testing
- Survey
- Where
- Qatar
- Volunteers
- 25,000 people
- Sponsor
- Hamad Medical Corporation
Stress Disorders, Post-Traumatic, Combat Disorders
Traumatic Nightmares Treated by NightWare (To Arouse Not Awaken)
This study will provide preliminary estimates of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare
- Trial name
- TNT/NW (NCT03795987)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NightWare
PTSD
Safety and Efficacy Study of TNX-102 SL in Participants With PTSD
This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, fixed-dose study that will investigate the efficacy and safety of 5.6 mg TNX-102 SL (2 x 2.8 mg tablets)-a sublingual formulation of cyclobenzaprine.
- Trial name
- NCT05372887
- Testing
- TNX-102 SL
- Where
- 3 sites in Kenya
- Sponsor
- Tonix Pharmaceuticals, Inc.
Post-traumatic Stress Disorder, Adjustment Disorders
Pivotal Trial of SAT-014 for Trauma and Stressor-Related Disorder Symptoms
The aim of this study is to evaluate the efficacy of SAt-014, a software as a medical device (SaMD), in alleviating symptoms of trauma and stressor-related disorders in patients with post-traumatic stress disorder (PTSD) or…
- Trial name
- NCT06734858
- Testing
- SAT014, Control
- Where
- 5 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
PTSD
Ganaxolone in Posttraumatic Stress Disorder (PTSD)
This Phase 2 proof-of-concept study is a double-blind, randomized, placebo-controlled, 15-week investigation of ganaxolone versus placebo for the treatment of Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01339689
- Testing
- Ganaxolone
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Marinus Pharmaceuticals
Post-Traumatic Stress Disorder
A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD)
The purpose of the present study is to evaluate the safety and efficacy of Brainsway Deep TMS (DTMS) for the treatment of PTSD.
- Trial name
- NCT02479906
- Testing
- Deep TMS System
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 203 people
- Sponsor
- Brainsway
Depressive Disorder
Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression
This is a prospective, multicenter, randomized, double-blind, controlled study to evaluate the effectiveness of PEER Interactive to inform treatment in subjects with a primary diagnosis of depression with comorbidity of…
- Trial name
- NCT01794559
- Testing
- PEER Interactive Report
- Where
- 2 sites in United States
- Volunteers
- 1,922 people
- Sponsor
- MYnd Analytics
PTSD
Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD
18-week, crossover, double-blind, randomized, placebo controlled proof-of-concept study to assess the efficacy and safety of SRX246 (160 mg bid) vs placebo in 52 adult veterans and civilians with a primary diagnosis of PTSD.
- Trial name
- NCT02733614
- Testing
- SRX246
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Azevan Pharmaceuticals