Clinical trials: Post-Operative Adhesions
Urologic Cancer, Satisfaction, Patient
Telemedicine for Postoperative Follow-up After Oncological Surgeries
The study will be a prospective, randomized, non-inferiority, open-label study, to be carried out at the Cancer Institute of the State of São Paulo for 6 months and will include patients agreeing to voluntary participation upon…
- Conditions
- Urologic Cancer, Satisfaction, Patient, Surgery, Postoperative Adhesion
- Trial name
- NCT06282354
- Testing
- Type of post-operative appointment
- Volunteers
- 200 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Hernia of Abdominal Wall, Incisional Hernia
"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"
Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device…
- Trial name
- DM159 (NCT02328352)
- Testing
- BP selfstanding felt, PP mesh, BP intraperitoneal mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Prevention of Postoperative Adhesions
Effect of Intraperitoneal Insulin Administration After Laparoscopy in Insulin-Resistant Patients on Prevention of Postoperative Adhesion Recurrence: A Randomized Controlled Trial
Adhesion formation following laparoscopic pelvic surgery remains a significant cause of chronic pelvic pain, infertility, and surgical complications.
- Trial name
- NCT07007130
- Testing
- Actrapid insulin, Normal saline
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Infertility, Abnormal Uterine Bleeding (AUB)
Evaluation of the Uterine Cavity After Operative Hysteroscopy
This study will focus on evaluation of the uterine cavity after operative hysteroscopy using three dimensional transvaginal ultrasonography and office hysteroscopy to detect and residual or recurrent abnormalities or intrauterine…
- Conditions
- Infertility, Abnormal Uterine Bleeding (AUB), Intrauterine Adhesion, Submucous Leiomyoma of Uterus
- Trial name
- NCT06924437
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Adhesions, Ileus
A Study to Evaluate the Safety, Tolerability and Efficacy of LB1148 for Subjects Undergoing Elective Bowel Resection
The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of LB1148 in subjects undergoing elective bowel resection.
- Trial name
- NCT04100447
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Ronald Hurst, MD, FACS
Reduction of Postoperative Adhesions
Evaluation of the Feasibility, Safety, Initial Efficacy and Clinical Usability of FuseX Anti-Adhesion System
Evaluation of the feasibility, safety, initial efficacy and usability of FuseX Anti-Adhesion system toward further studies that will be powered to proved its safety and efficacy.
- Trial name
- NCT03820713
- Testing
- Concentrate of plasma coagulation factors, 0.9% saline
- Where
- 2 sites in Lithuania
- Volunteers
- 30 people
- Sponsor
- Eio Biomedical Ltd.
HIPEC, Gastro Intestinal Cancer
Effects of HIPEC on Postoperative Bowel Motility and Complications
This retrospective cohort study was conducted at our institution, involving patients with gastric cancer, appendiceal mucinous neoplasm, or colon cancer who underwent CRS with or without HIPEC between January 2017 and December…
- Conditions
- HIPEC, Gastro Intestinal Cancer, Adhesion Prevention, Bowel Functions
- Trial name
- NCT07353177
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- China
- Volunteers
- 193 people
- Sponsor
- Peking University People's Hospital
Adhesions, Colectomy
SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery
The purpose of this study is to determine if the use of SurgiWrapTM: (1) prevents/lowers the incidence of Grade 2 or higher soft tissue attachments under the incision made during abdominal surgery, (2) reduces post-operative…
- Trial name
- NCT00531739
- Testing
- Polylactic Acid Sheet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cytori Therapeutics
Abdominal Adhesions
Evaluation of the Safety and Effectiveness of Sepraspray™ in Reducing Post-surgical Adhesions
This study will examine the safety and efficacy of Sepraspray in the following model of abdominal surgery: total proctocolectomy and pelvic pouch with diverting ileostomy via laparotomy to treat ulcerative colitis or familial…
- Trial name
- NCT00665730
- Testing
- Sepraspray
- Where
- 6 sites in Czechia, Denmark and 3 more
- Volunteers
- 5 people
- Sponsor
- Genzyme, a Sanofi Company
Intrauterine Adhesion
Safety and Efficacy of Intrauterine Biological Barrier on Postoperative Adhesion After Hysteroscopic Adhesiolysis
To evaluate the safety and efficacy of Intrauterine Biological Barrier developed and produced by Chengdu TopRegMed Medical Technology Co., Ltd on postoperative adhesion after Hysteroscopic Adhesiolysis.
- Trial name
- NCT05475756
- Testing
- Intrauterine Biological Barrier, Intrauterine Adhesion Barrier Gel
- Where
- 6 sites in China
- Volunteers
- 264 people
- Sponsor
- Beijing Tiantan Hospital
Pelvic Adhesions, Post Hysterectomy Pain
Effects of Soft Tissue Mobilization and Pelvic Floor Muscle Exercises on Pelvic Adhesions
Adhesions are permanent tissue connections that are created by fibrin deposition between different tissue planes or organs. They are a part of the internal healing process and inflammatory reactions that go through several…
- Trial name
- NCT06658210
- Testing
- soft tissue mobilization with pelvic floor muscle exercises, soft tissue mobilization without pelvic floor muscle exercises
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Glottic Web of Larynx, Laryngeal Stenosis
Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords
To provide a novel therapy idea and method to solve the clinical problem of postoperative adhesion of bilateral vocal cords, patients enrolled in this study will be applied with curcumin on both wound sites of bilateral vocal…
- Conditions
- Glottic Web of Larynx, Laryngeal Stenosis, Glottic Carcinoma, Laryngeal Leucoplakia
- Trial name
- NCT05688488
- Testing
- Curcumin, Mitomycin-C
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Cesarean Section, Adhesions
Closure of Peritoneum at Cesarean Section and Postoperative Adhesion
Objective: To determine the effect of non-closure of the visceral and parietal peritoneum during Cesarean section on the formation of adhesions.
- Trial name
- cs adhesions (NCT01183000)
- Testing
- Closure of the peritoneum at cs
- Where
- 2 sites in Israel
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Adhesions
Safety Study of Polylactide-Caprolactone-Trimethylenecarbonate Copolymer for Post-Operative Adhesion Prophylaxis
The purpose of this study is to compare adhesion prophylaxis with polylactide-caprolactone-trimethylenecarbonate copolymer to icodextrin 4% in terms of safety, side effects and usability in addition to gaining early evidence of…
- Trial name
- NCT00597662
- Testing
- polylactide-caprolactone-trimethylenecarbonate copolymer, Icodextrin 4%
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
Colorectal Disorders, Incisional Hernia
Incisional Hernia and Adhesion-Related Bowel Obstruction
Despite of technological advances in surgery, incisional hernia and bowel obstruction remain frequent surgical complications. To date, the relationship between these two types of surgery and the occurrence of incisional hernia…
- Conditions
- Colorectal Disorders, Incisional Hernia, Bowel Obstruction
- Trial name
- NCT02116881
- Testing
- Colorectal Surgery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Post-operative Adhesion(s)
Postoperative Intensive Care Surveillance
Several score systems were created to stratify perioperative risk and predict mortality. The study rises from the needing of a rapid and simple system to identify the patient worthy of Postoperative Intensive Surveillance.
- Trial name
- PoIS (NCT02894788)
- Testing
- ICU admission
- Where
- Italy
- Volunteers
- 2,498 people
- Sponsor
- Istituto Clinico Humanitas
Postoperative Adhesion, Peritoneal Adhesion, Nos
Efficacy of Sprayable PEG Barrier in Gynecologic Laparoscopy
The purpose of the study is to investigate whether sprayable PEG barrier is effective in reducing adhesions in laparoscopic gynecologic surgery.
- Trial name
- NCT01187680
- Testing
- Spraygel, Control
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Radboud University Medical Center