Clinical trials: Post-Operative Adhesions
Adhesions
Pediatric Multicenter Study of REPEL-CV
This trial will study REPEL-CV for reducing post operative adhesions following cardiovascular (cv) surgery.
- Trial name
- NCT00116233
- Testing
- REPEL-CV
- Where
- United States
- Sponsor
- SyntheMed
Intrauterine Adhesion
Heparin Solution Versus Anti-adhesion Barrier Gel for Intrauterine Adhesions Prevention After Operative Hysteroscopy
The aim of this study is to compare the efficacy of intrauterine application of heparin solution to the use of hyaluronic acid barrier gel for the prevention of intrauterine adhesion formation after operative hysteroscopy.
- Trial name
- NCT05257213
- Testing
- Heparin solution, Anti-adhesion barrier gel
- Where
- 2 sites in Bulgaria
- Volunteers
- 100 people
- Sponsor
- Nadezhda Women's Health Hospital
Chronic Pain, Tissue Adhesion
Laparoscopic Adhesiolysis for Chronic Abdominal Pain Revisited
Chronic abdominal and pelvic pain is a common complaint following peritoneal surgery, affecting 20-40% of patients. Adhesions account for 60% of chronic postoperative pain cases, suggesting that adhesiolysis can play an important…
- Trial name
- NCT02983916
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Radboud University Medical Center
Myoma
Safety and Efficacy Study of a Hydrogel, Applied Following Removal of Myomas During Gynecologic Surgery, Administered for the Prevention/Reduction of Postoperative Adhesion Formation
The purpose of this study was to determine whether the adhesion prevention gel was safe to use, and was effective for the prevention/reduction of adhesion formation that typically occurs following gynecological surgery to remove…
- Trial name
- NCT00562471
- Testing
- Adhibit Adhesion Prevention Gel, Standard of Care Comparator
- Where
- 6 sites in Canada, Germany and 1 more
- Volunteers
- 76 people
- Sponsor
- Angiotech Pharmaceuticals
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Efficacy and Safety of Ionized Atelocollagen Adhesion Barrier (Collabarrier®) in Spine Surgery
This multicenter, randomized, subject- and evaluator-blinded, active-controlled, non-inferiority clinical trial was conducted to evaluate the efficacy and safety of Collabarrier®, a collagen-based adhesion barrier, compared to…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Epidural Fibrosis, Postoperative Adhesion
- Trial name
- NCT07153822
- Testing
- Collagen-based adhesion barrier, Sodium hyaluronate(HA) and Sodium Carboxymethylcellulose(CMC)-based adhesion barrier
- Where
- 6 sites in South Korea
- Volunteers
- 69 people
- Sponsor
- DALIM TISSEN Co., Ltd.
Post Operative Adhesions
Role of Hyaluronic Acid in the Prevention of Post-operative Adhesions: a RCT
The objective of study is to determine the effect of hyaluronic acid on the formation of post-operative adhesions. It will be a randomized control trial comparing the product against normal saline.
- Trial name
- HiB (NCT02790177)
- Testing
- Hyaluronic Acid, NORMAL SALINE
- Volunteers
- 150 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Impacted Mandibular Third Molar, Postoperative Wound Healing
Soft Tissue Healing and Bacterial Load With Triclosan-Coated Sutures After Impacted Mandibular Third Molar Surgery
The goal of this clinical trial is to learn if triclosan-coated absorbable stitches (polyglactin 910 sutures coated with triclosan, an antibacterial agent) help soft tissue heal better and have fewer bacteria stuck to the…
- Trial name
- NCT07386366
- Testing
- Triclosan-coated Polyglactin 910 suture, Non-coated polyglactin 910 suture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Thyroid Carcinoma
A Study Into the Effect of Seprafilm in Open Total Thyroidectomy
The investigators intend to determine the role of Seprafilm, a popular anti-adhesive agent in minimising internal adhesion formation in the neck after thyroid surgery and therefore reduce swallowing discomfort experienced by…
- Trial name
- NCT01865838
- Testing
- Seprafilm (Sanofi, USA)
- Where
- 2 sites in Singapore
- Volunteers
- 19 people
- Sponsor
- National Cancer Centre, Singapore
Abdominal Adhesions
Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", With a Single Intraperitoneal Use After Surgery in Adult Patients With Acute Phlegmonous Appendicitis
The purpose of the clinical trials is the evaluation of the effectiveness and safety of a single intraperitoneal use of the drug "Antispike, gel, 100 g in a bottle" produced by Unitary Enterprise Unitehprom BSU, Belarus in…
- Trial name
- OLTOSPAN-02 (NCT06365632)
- Testing
- Antispike gel, 100 g in a flask, produced by UNITEHPROM BSU, Republic of Belarus, antegrade appendectomy
- Where
- Belarus
- Volunteers
- 100 people
- Sponsor
- Research Institute for Physical Chemical Problems of the Belarusian State University
Endometriosis
Post-operative Ovarian Adhesion Study in Women With Endometriosis
Endometriosis is a common gynaecological condition which typically present with pelvic pain and fertility problems. It is caused by tissues which are similar to the lining of the womb growing inside the women's pelvis.
- Trial name
- NCT01989260
- Testing
- Anti-adhesive gel
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College London Hospitals
Intrauterine Adhesion
Three-dimensional Ultrasound Applying in Assessment of Intrauterine Adhesions
In this prospective, multicenter, large-scale study，the investigators wish to examine the accuracy of several three-dimensional ultrasound anatomical and vascular parameters in diagnosing IUA when compared to the gold standard of…
- Trial name
- NCT04930913
- Testing
- Three-dimensional Ultrasound
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Tissue Adhesions
The Effect of Adhesiolysis During Elective Abdominal Surgery on Per- and Postoperative Complication, Quality of Life and Socioeconomic Costs
Official title: LAPAD - A prospective study on the effect of adhesiolysis during elective laparotomy or laparoscopy on per- and postoperative complication, quality of life and socioeconomic costs Background: With improved…
- Trial name
- LAPAD (NCT01236625)
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 752 people
- Sponsor
- Radboud University Medical Center
Pain, Shoulder, Postoperative Pain
The Effects of Qigong Exercise Training After Thoracotomy
Postoperative pulmonary complications after thoracotomy cause morbidity and mortality. Although the causes of postoperative pulmonary complication are multifactorial, respiratory muscle dysfunction is a contributing factor to the…
- Conditions
- Pain, Shoulder, Postoperative Pain, Joint Adhesion, Muscle Weakness
- Trial name
- NCT05470192
- Testing
- Qigong exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Rotator Cuff Injuries, Pain, Postoperative
Effect of Extracorporeal Shock Wave Therapy After Arthroscopic Rotator Cuff Repair
Although radial extracorporeal shock wave therapy (rESWT) has proven to be an effective treatment, the effectiveness of the treatment has so far been controversial.
- Conditions
- Rotator Cuff Injuries, Pain, Postoperative, Tissue Adhesion
- Trial name
- NCT04848103
- Testing
- Radial extracorporeal shockwave therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Sahmyook University
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Intrauterine Adhesion
The Efficacy of A New Crosslinked Hyaluronan Gel in Prevention of Intrauterine Adhesion
Using American Fertility Society classification of intrauterine adhesions, the efficacy of a new crosslinked hyaluronan gel in reducing intrauterine adhesion formation after dilatation and curettage for delayed miscarriage in…
- Trial name
- NCT03353909
- Testing
- new crosslinked hyaluronan gel
- Volunteers
- 300 people
- Sponsor
- BioRegen Biomedical (Changzhou) Co., Ltd
Tissue Adhesions
Safety Study of Use of Hyaluronic Acid Gel To Prevent Intrauterine Adhesions In Hysteroscopic Surgery
Operations in the uterus are currently possible using a hysteroscope. One serious though rare complication of such procedures is the development of intra-uterine adhesions. There currently are no methods to prevent this.
- Trial name
- NCT01464528
- Testing
- Hyaluronan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Ileus, Post-Operative Adhesions
A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection
The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel…
- Trial name
- PROFILE (NCT02836470)
- Testing
- LB1148
- Where
- 28 sites in United States
- Volunteers
- 112 people
- Sponsor
- Palisade Bio
Intrauterine Adhesion
Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion
This study aimed To investigate the effects of estrogen in combination with aspirin and intrauterine balloon on the uterine endometrial repair and reproductive prognosis in patients after surgery for severe intrauterine adhesion .
- Trial name
- NCT02744716
- Testing
- Aspirin, intrauterine balloon
- Where
- China
- Volunteers
- 114 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Post-surgery Adhesion Formation
Safety Study Investigating Local Tolerability and Pharmacokinetics of PXL01 in Healthy Volunteers
The main purpose of this study is to determine whether three different single doses of PXL01 are safe and well tolerated by healthy volunteers. The pharmacokinetic properties of PXL01 (same doses) will also be investigated.
- Trial name
- NCT00860080
- Testing
- PXL01
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- PharmaSurgics AB