Clinical trials: Post-Op Infection
Coronary Artery Disease, Postoperative Complications
Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery
This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery.
- Conditions
- Coronary Artery Disease, Postoperative Complications, Aortic Valve Stenosis, Mitral Valve Disease
- Trial name
- PREFER-CABG (NCT03574311)
- Testing
- Ferric carboxymaltose, Physiological saline
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- Turku University Hospital
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
C. Acnes, Phototherapy
Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis
This is a prospective, randomized controlled trial to evaluation the ability of 5-aminolevulinic acid HCL topical solution photodynamic therapy to decrease the colonization of Cutibacterium acnes (C.
- Conditions
- C. Acnes, Phototherapy, Postoperative Infection, Arthroscopic Rotator Cuff Repair
- Trial name
- NCT04636242
- Testing
- Skin Biopsy, 5 Aminolevulinic Acid + Phototherapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Tooth Extraction, Post-Op Complication
Antibiotic Therapy in Erupted Tooth Extractions
Evaluation of the efficacy of amox+clav and of a probiotic after tooth extraction. the aim is to evaluate efficacy of antibiotic therapy after tooth extractions in preventing infections as compared to no therapy, and efficacy of…
- Conditions
- Tooth Extraction, Post-Op Complication, Amoxicillin
- Trial name
- NCT04082598
- Testing
- Amoxicillin Clavulanate, Bifidobacterium longum and Lactoferrin
- Volunteers
- 165 people
- Sponsor
- Antonio Barone
Root Canal Infection, Endodontic Disease
Occurrence of Post-op Pain Following Gentlewave
This is a clinical study that will investigate the occurrence of post-operative discomfort following the use of the Gentlewave System for root canal disinfection and irrigation.
- Conditions
- Root Canal Infection, Endodontic Disease, Endodontic Inflammation, Post-Operative Pain
- Trial name
- NCT03635515
- Testing
- Gentlewave, Standard Endodontic Protocol
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Body Temperature, Postoperative Infection
Steadysense -Early Detection of Postoperative Infections Through Continuous Temperature Measurement
The goal of this observational study is to review whether postoperative infections can be detected earlier by a continuous measurement of body temperature of patients compared to single daily measurements.
- Conditions
- Body Temperature, Postoperative Infection, Pneumonia
- Trial name
- NCT06044428
- Testing
- Steadytemp®
- Where
- Austria
- Volunteers
- 103 people
- Sponsor
- Medical University of Graz
Severe Hyperglycemia, Postoperative Infection
Intraoperative Hyperglycemia and Infections After Orthopedic Surgery
Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy.
- Conditions
- Severe Hyperglycemia, Postoperative Infection, Orthopedic Patients
- Trial name
- NCT03903354
- Testing
- Incidence of infections within 7 days postoperatively
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Federico Bilotta
Lumbar Vertebrae, Surgical Site Infection
Dixon MRI Imaging Histology for Predicting Postoperative Infection in Posterior Lumbar Fusion for Myasthenia Gravis
Sarcopenia is an age-related condition that manifests itself as a persistent decrease in muscle mass and function, which may lead to decreased physical function, increased risk of disease, and reduced quality of life.
- Conditions
- Lumbar Vertebrae, Surgical Site Infection, Radiomics
- Trial name
- NCT06805643
- Volunteers
- 1,300 people
- Sponsor
- The First People's Hospital of Yunnan
Surgical Site Infections, Post Operative Complication
2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients
Surgical site infection (SSI) following spinal surgery is a frequent complication and results in higher morbidity, mortality and healthcare costs.
- Trial name
- DeSSI (NCT02490631)
- Testing
- 2% chlorhexidine gluconate cloths
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Vanderbilt University
Bacterial Infection, Postoperative Infection
Neutrophil CD64 and Procalcitonin as Novel Biomarkers for Postoperative Infections
Postoperative complications, especially bacterial infections, are relatively common and cause increased morbidity and mortality.
- Conditions
- Bacterial Infection, Postoperative Infection, Abdominal Infection
- Trial name
- NCT01250574
- Testing
- CD64 and Procalcitonin
- Where
- Norway
- Volunteers
- 173 people
- Sponsor
- University Hospital, Akershus
Hyperglycemia, Craniotomy
Impact of Severe Intraoperative Hyperglycemia on Infection Rate After Elective Intracranial Interventions
Severe intraoperative hyperglycemia (SIH) is recognized as one of the important risk factors for the increasing of the postoperative infections rate, which can negatively affect the final outcome of surgical treatment.
- Conditions
- Hyperglycemia, Craniotomy, Infection Post Op
- Trial name
- NCT04285359
- Testing
- Intracranial Interventions
- Where
- 2 sites in Italy, Russia
- Volunteers
- 514 people
- Sponsor
- Burdenko Neurosurgery Institute
Periodontitis, Heart Valve Disease
Effect of Preoperative Periodontal Treatment on Postoperative Infection and Mortality After Aortic and Mitral Valve Surgery
This retrospective observational study aims to evaluate the effect of preoperative periodontal treatment on postoperative infection and mortality in patients undergoing aortic and mitral valve surgery.
- Conditions
- Periodontitis, Heart Valve Disease, Postoperative Infection, Cardiovascular Disease
- Trial name
- Perio-CVS (NCT07626801)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University - Cerrahpasa
Sepsis, Septic Shock
The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients
Surgical trauma elicits an immune response aiming to initiate healing and remove debris and damaged tissue locally at the wound site (1).
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe, Post-Op Complication
- Trial name
- NCT04117568
- Testing
- Blood sampling
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Göteborg University
Post-Op Complication
A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery
The purpose and objectives of this study is to investigate whether reducing the existing arm restrictions on patients who receive Cardiac Implantable Electronic Devices (CIED) will result in an improved patient experience post…
- Trial name
- LENIENT (NCT04915261)
- Testing
- Lenient Arm Restriction, Strict Arm Restriction
- Where
- Canada
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Cataract, Endophthalmitis
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision).
- Trial name
- NCT00730938
- Testing
- cefuroxime
- Where
- Kenya
- Volunteers
- 45 people
- Sponsor
- Presbyterian Church East Africa Kikuyu Hospital
Kidney Stones
Effect of Negative Pressure Suction on Fluid Absorption and Infection in Flexible Ureteroscopy
The goal of this observational study is to learn about the effects of using negative pressure suction during retrograde intrarenal surgery (RIRS) in patients aged 18 and older with kidney stones.
- Trial name
- NCT07492147
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Lanzhou University Second Hospital
Surgery, Covid19
GlobalSurg-CovidSurg Week
Observational study to determine the optimal timing for surgery following SARS-CoV-2 infection and assess key global surgery indicators.
- Conditions
- Surgery, Covid19, Post-Op Complication
- Trial name
- NCT04509986
- Volunteers
- 1,000 people
- Sponsor
- University of Birmingham
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
Intra-abdominal Infection, Critical Illness
Innate Immune Response Monitoring Via Monocyte HLA-DR in Severe Intra-abdominal Infections at Risk of Fungal Infection
Intra-abdominal candidiasis (IAC) is a frequent and severe fungal infection in critically ill patients, often diagnosed late. Its pathophysiology remains unclear, particularly regarding why some patients develop invasive…
- Conditions
- Intra-abdominal Infection, Critical Illness, Post-Op Infection, Immunization; Sepsis
- Trial name
- CANDIRIS (NCT07130799)
- Testing
- Immunomonitoring
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Intestinal Obstruction, Colorectal Cancer
Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel Obstruction
Despite modern approaches to the diagnosis and treatment of acute bowel obstruction (ABO), postoperative mortality ranges from 5 to 32%, and complications occur up 23% of cases.
- Conditions
- Intestinal Obstruction, Colorectal Cancer, Post-Op Complication, Systemic Inflammatory Response Syndrome
- Trial name
- NCT05229822
- Testing
- LBP, sCD14-ST, 16s rRNA
- Where
- Kazakhstan
- Volunteers
- 150 people
- Sponsor
- Karaganda Medical University