Clinical trials: Post-Op Infection
Postoperative Infection
Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery
Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation.
- Trial name
- NCT06177444
- Testing
- Antibiotic
- Where
- Denmark
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Postoperative Infection, Abdominal Surgery
Study for Rapid Diagnosis of Postoperative Abdominal Infection
This is a prospective and exploratory study, which utilizes non-targeted metagenomic next-generation sequencing (mNGS) detecting drain fluid from patients who are suspected of postoperative abdominal infection.
- Conditions
- Postoperative Infection, Abdominal Surgery, Intra-abdominal Infection, Postoperative Fever
- Trial name
- NCT05187871
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hyperglycemia, Postoperative Infection
Hyperglycemia in Neurosurgery
Poor glycemic control is recognized as a risk factor for postoperative infection. For the neurosurgical patient, postoperative infection can lead to devastating complications such as meningitis, encephalitis and death.
- Trial name
- NCT05236751
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Perforated Appendicitis, Postoperative Infection
Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis
After appendix has been removed for perforated appendicitis, patients will receive postoperative antibiotics. In the last 5 years, the literature has transitioned from a 3 -drug therapy to 2-drug therapy.
- Trial name
- NCT03289351
- Testing
- Piperacillin, Tazobactam Drug Combination
- Where
- 2 sites in United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Cesarean Section
The Effect of Forced Air Warming During Cesarean Section on Postoperative Infectious Morbidity
The purpose of this study will be to assess whether forced air warming decreases the rate of surgical site infections following cesarean section.
- Trial name
- NCT00696462
- Testing
- forced-air warming
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University
Postoperative Infection, Geriatrics
Elderly Patients Surgical Site Infection Phenotypes Identification
This study utilizes Latent Class Analysis (LCA) to identify phenotypes of Surgical Site Infection (SSI) in elderly patients following non-cardiac surgery.
- Conditions
- Postoperative Infection, Geriatrics, Prediction, Surgical Site Infection
- Trial name
- NCT06612177
- Where
- China
- Volunteers
- 42,532 people, healthy volunteers welcome
- Sponsor
- Weidong Mi
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Hyperoxia
Hyperoxygenation in Anesthetized Children
This study is aiming at assessing the effect of inspired oxygen fraction during general anesthesia on children's lung mechanics and volume.
- Trial name
- OXPED (NCT02384616)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Walid HABRE
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
C. Acnes, Phototherapy
Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis
This is a prospective, randomized controlled trial to evaluation the ability of 5-aminolevulinic acid HCL topical solution photodynamic therapy to decrease the colonization of Cutibacterium acnes (C.
- Conditions
- C. Acnes, Phototherapy, Postoperative Infection, Arthroscopic Rotator Cuff Repair
- Trial name
- NCT04636242
- Testing
- Skin Biopsy, 5 Aminolevulinic Acid + Phototherapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Root Canal Infection, Endodontic Disease
Occurrence of Post-op Pain Following Gentlewave
This is a clinical study that will investigate the occurrence of post-operative discomfort following the use of the Gentlewave System for root canal disinfection and irrigation.
- Conditions
- Root Canal Infection, Endodontic Disease, Endodontic Inflammation, Post-Operative Pain
- Trial name
- NCT03635515
- Testing
- Gentlewave, Standard Endodontic Protocol
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Post-Op Complication
A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery
The purpose and objectives of this study is to investigate whether reducing the existing arm restrictions on patients who receive Cardiac Implantable Electronic Devices (CIED) will result in an improved patient experience post…
- Trial name
- LENIENT (NCT04915261)
- Testing
- Lenient Arm Restriction, Strict Arm Restriction
- Where
- Canada
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Preventative Laparoscopic Hysterectomy
Chlorhexidine vs Povidone Iodine Vaginal Prep in Decreasing Postoperative Infection in Total Laparoscopic Hysterectomy
This is a randomized control trial which will randomize patients who will be undergoing laparoscopic (conventional or robotic assisted) total hysterectomy to vaginal prep with 4% chlorhexidine gluconate vs 10% povidone iodine.
- Trial name
- NCT05692986
- Testing
- A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections
Postpartum infection if a major cause of maternal morbidity and mortality and surgical site infections are some of the common complications following cesarean section.
- Conditions
- Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
- Trial name
- NCT05392400
- Testing
- Steri3X, Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Organ Transplantation, Immunosuppressive Agents
Immunosuppressants to Postoperative Infection and Death
The goal of this observational study is to explore the different immunosuppressive agents and related outcomes in organ transplantation patients in Taiwan.
- Conditions
- Organ Transplantation, Immunosuppressive Agents, Cohort Study
- Trial name
- NCT06121804
- Testing
- Immunosuppressive Agents
- Where
- Taiwan
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Surgical Site Infection, Post-Op Complication
Perioperative Immunonutrition in Patients Undergoing Gynecologic or General Elective Surgery (PURPOSE)
The objective of the implementation pilot is to assess the practicality of introducing a perioperative immunonutrition protocol into a hospital environment as well as a true measure of impact on the rate of surgical site…
- Trial name
- PURPOSE (NCT04057092)
- Testing
- Dietary Supplement INergy-FLD
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation