Clinical trials: Post-Op Complication
Nausea, Postoperative, Vomiting, Postoperative
Optimal Dosing of Preoperative Gabapentin for Prevention of Postoperative Nausea and Vomiting
Overall incidence of postoperative nausea and vomiting (PONV) after general anesthesia is 40-90 % . gabapentin has been incorporated into "fast-track" packages and improved recovery during surgery protocols to avoid unintended…
- Conditions
- Nausea, Postoperative, Vomiting, Postoperative, Pain, Postoperative
- Trial name
- NCT04622618
- Testing
- Gabapentin
- Where
- 2 sites in Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Failed Back Surgery Syndrome
Clinical Decision Support System (CDSS) in Neurostimulation Therapy
Chronic pain is correlated with alterations in the structure and function of the brain, developed according to the phenotype of pain.
- Trial name
- CDSS (NCT04735159)
- Testing
- SCS implanted with Precision SpectraTM
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- General University Hospital of Valencia
Post-Operative Pain, Pelvic Organ Prolapse
Post-Operative Pain Control Using Direct Continuous Bupivacaine Infusion After Pelvic Organ Prolapse Repair
This prospective randomized controlled study will determine the efficacy of continuous local anesthesia at decreasing pain scores compared to patient controlled analgesia for pelvic organ prolapse procedures including posterior…
- Trial name
- NCT00695240
- Testing
- Continuous bupivacaine analgesia infusion (ON-Q PainBuster Post-Op Pain Relief System)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Kansas City, Missouri
Postoperative Pain
Efficacy of Buprenorphine on Postoperative Endodontic Analgesia
To see whether the addition of buprenorphone to local anesthesia will lengthen postoperative analgesia for endodontic pain
- Trial name
- EBPEA (NCT03268278)
- Testing
- Buprenorphine, Sterile saline, lidocaine, epinephrine (Local anesthetic)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Gender, Postoperative Pain
Acute Postthoracotomy Pain - Impact of Gender
Adequate analgesia in thoracic surgery is essential to prevent severe postoperative complications, especially respiratory problems.
- Conditions
- Gender, Postoperative Pain, Thoracotomy, Analgesia
- Trial name
- NCT03281213
- Testing
- Thoracotomy
- Where
- Austria
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Incisional Hernia
Suture Repair vs Mesh Repair for Incisional Hernia
The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques.
- Trial name
- NCT05599750
- Testing
- Incisional hernia repair
- Where
- 5 sites in United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Clayton Petro
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Post Operative Pain
Laparoscopic-guided TAP Block vs Epidural Analgesia
The LAPTAP trial will provide evidence on preferred post-operative analgesia method in elective laparoscopic colon surgery.
- Trial name
- NCT05214261
- Testing
- Safety and efficiency of post operative analgesia between laparoscopic-assisted TAP block and epidural analgesia
- Where
- Finland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Nasal Sinus; Inflammation, Opioid Abuse
Pain Management Following Sinus Surgery
This Study evaluates the effect of adding Non-steroidal anti-inflammatories (NSAIDs) to the post-operative pain management of sinus surgery patients and wether or not this addition reduces or eliminates the need for narcotic pain…
- Conditions
- Nasal Sinus; Inflammation, Opioid Abuse, Pain, Postoperative
- Trial name
- NCT03822962
- Testing
- Ibuprofen 600Mg Tablet, Standard Regimen | Tylenol
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Pain, Postoperative, Pulmonary Atelectasis
Paravertebral Block Versus Erector Spinae Plane Block for Modified Radical Mastectomy in Womens.
postoperative pain following Modified radical mastectomy is severe specially after dissection of tissues .paravertebral plane block provides an excellent postoperative analgesia for women's,but it carry the risk of pneumothorax…
- Conditions
- Pain, Postoperative, Pulmonary Atelectasis, Mastectomy
- Trial name
- NCT03614091
- Testing
- Erector spinae plane block, Paravertebral plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain After Knee Arthroscopy
Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia
arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.
- Trial name
- NCT03530280
- Testing
- pregabalin (lyrica), adductor canal block including bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Ischemia-Reperfusion Injury, Atherosclerosis
Does a Seven Day Treatment With Dipyridamole Induce Protection Against Ischemia-Reperfusion Injury?
This study is performed to determine whether a seven day treatment with dipyridamole (slow release, 200mg twice daily) can induce a protective effect against ischemia-reperfusion injury, after ischemic exercise of the…
- Trial name
- NCT00457405
- Testing
- dipyridamole
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
ACL, Postoperative Pain
Exparel vs Block for ACL Reconstruction
Liposomal bupivacaine or Exparel (Pacira Biosciences) is a long-lasting nonopioid analgesic that was initially utilized as an infiltrative agent but has more recently become U.S.
- Trial name
- NCT06006624
- Testing
- Exparel 30 mL, 0.5% bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Post Operative Pain, Inflammation
The Effect of Different Intraradicular Cryotherapy on Post-operative Pain and the Level of Substance P
The aim of this clinical trial is to evaluate the effect of using intra-radicular cryotherapy technique in the form of irrigation with cold sodium hypochlorite The main questions to answer are: 1.
- Trial name
- NCT06106386
- Testing
- cryotherapy
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain, Shoulder Pain
Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy
Postoperative shoulder pain is often reported to be particularly bothersome after laparoscopy. The benefits of local anesthetic, such as bupivacaine, applied to subcutaneous tissue for general postoperative pain management after…
- Trial name
- NCT07400146
- Testing
- Instillation of Bupivacaine with epinephrine over the diaphragm
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Pain
Continuous Lumbar Plexus Block for Postoperative Pain Control After Total Hip Arthroplasty
Continuous lumbar plexus and femoral blocks have been demonstrated to provide effective postoperative analgesia of the lower extremity following total joint arthroplasty.
- Trial name
- NCT00790179
- Testing
- continuous infusion of ropivacaine via CLPB vs. CFB vs IV PCA
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pain, Postoperative, Narcotic Use
Bupivacaine for Post-operative Pain in Mohs
Mohs micrographic surgery (MMS) is regarded as the gold standard for the treatment of high-risk nonmelanoma skin cancer (NMSC). Pain after MMS peaks on the day of surgery and slowly decreases thereafter.
- Trial name
- NCT04362566
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
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