Clinical trials: Post-COVID-19 Syndrome
COVID-19
BREATHE: Virtual Self-management for Long COVID-19
A mixed-methods evaluation of a virtual self-management program for people living with long COVID in Alberta.
- Trial name
- NCT05107440
- Testing
- BREATHE
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Calgary
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Long COVID-19
Effects of Exercise Training on Patients With Long COVID-19
Effects of Exercise training on Patients With Long COVID-19, is a single-center, randomized, controlled trial designed to evaluate the effects of 4- week aerobic exercise administered to patients with long COVID-19 symptoms.
- Trial name
- NCT05961462
- Testing
- Exercise training
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Guangdong Provincial People's Hospital
Xerostomia, COVID-19
The Use of Photobiomodulation in the Treatment of Oral Complaints of Long COVID-19.A Randomized Controlled Trial.
Coronavirus (COVID-19) is a newly emerging zoonotic agent that emerged in December 2019 in China (2019-nCoV) as a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV -2).
- Conditions
- Xerostomia, COVID-19, Long COVID, Persistent COVID-19
- Trial name
- NCT05760092
- Testing
- Institutional standard treatment for xerostomia and Long Covid, Photobiomodulation Therapy
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Nove de Julho
Sars-CoV-2 Infection, Long Covid19
Long Term Outcomes in COVID-19 Patients Recruited in the CORIST Project
Months after seemingly recovering from COVID-19, many patients continue to suffer from major long-term effects. Interestingly, the existence of direct link between the severity of the disease in its acute phase and the severity…
- Trial name
- CORIST-2 (NCT04907890)
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Long COVID-19 Syndrome, Post COVID Syndrome Long Covid
Inspiratory Muscle Pressure and Diaphragmatic Strength in Women With Long COVID-19: A Pressure Biofeedback-Guided Training Study
COVID-19 is an infectious disease that can cause long-term health problems even after the acute infection has resolved. Many people who have recovered from COVID-19 continue to experience breathing difficulties, fatigue, and…
- Conditions
- Long COVID-19 Syndrome, Post COVID Syndrome Long Covid, Post COVID-19 Syndrome
- Trial name
- NCT07397130
- Testing
- Pressure Biofeedback Unit
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- RSUP Persahabatan
Post-intensive Care Syndrome, COVID-19
Clinical and Functional Characteristics of Patients Admitted for Severe COVID-19 Pneumonia
This research protocol aims to evaluate the impact of severe COVID-19 pneumonia requiring invasive mechanical ventilation (IMV) on health-related quality of life (HRQoL), functional capacity, muscle strength, and nutritional…
- Trial name
- EQOL-COVID (NCT06727474)
- Testing
- Health-Related Quality of Life (HRQoL) with EQ-5D-3L
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Long COVID, Post-Acute Sequelae of COVID-19
Mind Body Intervention for Long COVID-19
The goal of this study is to determine if a mind-body intervention can help people suffering from symptoms associated with Long COVID.
- Conditions
- Long COVID, Post-Acute Sequelae of COVID-19, COVID Long-Haul
- Trial name
- NCT06045338
- Testing
- Mind Body Intervention #1
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Beth Israel Deaconess Medical Center
Long COVID
Study of LAU-7b for the Treatment of Long COVID in Adults
ESSOR is a double-blind, placebo-controlled study of the orally-administered antiviral and inflammation-controlling LAU-7b for the treatment of adults with Long COVID and moderate to severe symptoms.
- Trial name
- ESSOR (NCT05999435)
- Testing
- LAU-7b for 3 cycles
- Where
- 5 sites in Canada
- Volunteers
- 272 people
- Sponsor
- Laurent Pharmaceuticals Inc.
ME/CFS, Fibromyalgia (FM)
Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study
Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.
- Conditions
- ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
- Trial name
- NCT07874217
- Testing
- Cryotherapy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Post-Acute COVID-19, Post Acute COVID-19 Syndrome
Safety and Dosage of a Computerized Cognitive Training Program for Cognitive Dysfunction After COVID-19
The goal of this Phase I/II clinical trial is to assess the safety and maximum tolerated training time of a self-administered computerized cognitive training (CCT) in individuals with cognitive dysfunction as a consequence of…
- Conditions
- Post-Acute COVID-19, Post Acute COVID-19 Syndrome, Cognitive Dysfunction, Cognitive Impairment
- Trial name
- CCTLongCOVID (NCT05582603)
- Testing
- CCT Long COVID
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio de Nebrija
Post-COVID-19 Syndrome, Back Pain
Kinesiotaping Versus Physiotherapy for Post-Covid-19 Back Pain
Objective: This study aims to compare and evaluate the effectiveness of kinesiotaping and traditional physiotherapy methods, which are frequently used in the treatment of musculoskeletal diseases, on mid-back pain (MBP) developed…
- Conditions
- Post-COVID-19 Syndrome, Back Pain, Musculoskeletal Pain
- Trial name
- NCT07744451
- Testing
- Kinesiotaping, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Medipol University
Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Diagnostic and Clinical Management of Non-Obstructive Myocardial Ischemia in Patients With Long Covid-19 Syndrome and New Onset Chest Pain
Long Covid-19 INOCA is an investigator-initiated, prospective, randomized, sham-controlled, single center study. Its objective is to investigate the benefits of tailored medical therapy according to the results of the coronary…
- Conditions
- Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Long COVID-19 Syndrome
- Trial name
- NCT07559994
- Testing
- Coronary functional test
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Post COVID-19 Syndrome, Rehabilitation
Implementation of Rehabilitation Program for Post COVID-19
Many people who have suffered from the effects of this disease might now be at risk of long-term impairment and disability. The extent of this impairment and disability is yet unknown, but it is clear from early research that…
- Trial name
- NCT04694768
- Testing
- Rehabilitation
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection, COVID-19
A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection
This is a Phase 2, randomized, parallel-group, double-blind, placebo-controlled, 14-week study designed to evaluate the efficacy and safety of TNX-102 SL 5.6 mg (2 x 2.8 mg tablets) taken once daily at bedtime for the management…
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection, COVID-19, Long COVID, Long Haul COVID
- Trial name
- PREVAIL (NCT05472090)
- Testing
- TNX-102 SL
- Where
- 29 sites in United States
- Volunteers
- 63 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Severe Acute Respiratory Syndrome, Coronavirus
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
This study aims to evaluate the safety and reactogenicity profile after 1 and 2 dose administrations of CVnCoV at different dose levels.
- Conditions
- Severe Acute Respiratory Syndrome, Coronavirus, SARS-CoV-2, COVID-19
- Trial name
- NCT04449276
- Testing
- CVnCoV Vaccine
- Where
- 4 sites in Belgium, Germany
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- CureVac
COVID-19, Chronic Heart Failure
Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection.
Aim of this prospective, interventional, single-center, randomized study is to evaluate the efficacy and safety of intermittent hypoxic-hyperoxic training (IHHT) as a rehabilitation method in patients with cardiovascular…
- Conditions
- COVID-19, Chronic Heart Failure, Hypertension, Arrhythmia
- Trial name
- NCT05379608
- Testing
- Intermittent hypoxic-hyperoxic training, Intermittent hypoxic-hyperoxic training/control
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Tachycardia, Dyspnea
Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study
Most patients with acute COVID-19 (Coronavirus 19) recover within weeks, however a significant number of individuals will develop the post-acute COVID 19 syndrome (PASC).
- Conditions
- Tachycardia, Dyspnea, COVID-19
- Trial name
- PEACE (NCT05096884)
- Testing
- Metoprolol Succinate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hackensack Meridian Health
Long COVID Syndrome
Effectiveness of a Personalized In-home Telerehabilitation Program on Self-Care in Patients With Long COVID
The goal of this clinical trial is to evaluate whether a 12-week tele-rehabilitation programme roduces medium-term improvements in self-management, fatigue and quality of life in patients affected by persistent COVID.
- Trial name
- RESPICARE (NCT06822179)
- Testing
- Education for self-management, Personalised exercise program, Usual Care
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- CEU San Pablo University
Post COVID Condition
Sonlicromanol in Post-COVID
The aim of this randomized, double-blind, placebo-controlled, phase II trial, is to study the effect of sonlicromanol on fatigue in patients with post-COVID who experience post-exertional malaise (PEM).
- Trial name
- SON4PEM (NCT07298005)
- Testing
- Sonlicromanol
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Michele van Vugt