Clinical trials: Post Traumatic Headache
Cervicogenic Headache
Specific Neck Rehabilitation for Unilateral Headache and Neck Pain, and Structural and Functional Changes in the Brain
In part 1 of the project clinical effect of specific neck rehabilitation for unilateral headache and neck pain (also termed cervicogenic headache) will be compared with standard primary health care.
- Trial name
- NCT02908984
- Testing
- Specific neck rehabilitation, Standard primary health care
- Where
- Norway
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Brain Concussion, Mild Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI).
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
- Trial name
- NCT06112093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Cervicogenic Headache, Chronic Neck Pain
Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls
The goal of this observational study is to compare physical findings across three adult groups. Cervicogenic headache (CGH) is a headache linked to a problem in the neck.
- Trial name
- NCT07776275
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Cervicogenic Headache
Pulsed Radiofrquency Targeting Mid Cervical Medial Branches Versus GON for Cervicogenic Headache
To detect the Clinical efficacy of pulsed radiofrequency treatment targeting the mid cervical medial branches versus greater occipital nerve for cervicogenic headache
- Trial name
- NCT05289414
- Testing
- Radiofrequency on mid cervical medial branches, Radiofrequency
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post-Traumatic Headache, Healthy
A Study to Evaluate Biomarker Signature to Predict the Persistence of Post-traumatic Headache
The purpose of this research study is to develop a model to help distinguish patients at high-risk for developing persistent post-traumatic headache from patients who experience headache recovery.
- Trial name
- NCT06132529
- Testing
- Brain Magnetic Resonance Imaging (MRI) Scan, Speech Sample, Electronic Daily Headache Diary
- Where
- 2 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Concussion Post Syndrome, Headaches Posttraumatic
Pediatric Concussion Outcomes
This is a randomized, placebo-controlled, double-blinded trial in which subjects with a post concussive headache meeting inclusion criterion will be assigned to one of two treatment groups: placebo or nortriptyline.
- Conditions
- Concussion Post Syndrome, Headaches Posttraumatic, Mild Traumatic Brain Injury
- Trial name
- PeCon (NCT04226365)
- Testing
- Nortriptyline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Occipital Neuralgia, Cervicogenic Headache
Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block
This study will compare the analgesic benefit of a traditional landmark-guided GON block with the ultrasound-guided approach over a four week period in patients with occipital neuralgia or cervicogenic headache.
- Conditions
- Occipital Neuralgia, Cervicogenic Headache, Migraine Without Aura
- Trial name
- NCT03478735
- Testing
- Ultrasound Guided Greater Occipital Nerve Block at C2, Landmark-Based Greater Occipital Nerve Block
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cervicogenic Headaches
Active and Passive Cervical Flexion-rotation Tests
Motion limitations have been previously reported in people with headaches originating from the neck/cervicogenic headaches. A test involving flexing and rotating the neck has been found useful to diagnose this type of headache.
- Trial name
- NCT02070172
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Des Moines University
Post-Traumatic Headache, Acute Pain
Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings
The investigators test a different technique using morphine to improve pain relief in patient visiting the emergency department with acute trauma pain, for this we are comparing three different methods of morphine administration…
- Trial name
- TIMORNEB (NCT02200185)
- Testing
- IV titrated morphine, Low dose nebulised morphine, High dose nebulised morphine
- Where
- Tunisia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Post Traumatic Headache
Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction
The purpose of this study is to determine whether naratriptan, a medication approved for treatment of migraine, is effective in the treatment of post traumatic headache associated with cognitive dysfunction.
- Trial name
- NCT00487578
- Testing
- naratriptan HCl
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cady, Roger, M.D.
Cervicogenic Headache
Additional Effects of Sternocleidomastoid Release With SNAGS in the Management of Cervicogenic Headache
Cervicogenic headache is a common type of headache in adults which causes disability and difficulty in everyday activities. According to the latest International Headache Society model, cervicogenic headache (CGH) is a secondary…
- Trial name
- NCT06534606
- Testing
- Electrotherapy and physical agents, Headache SNAGs, Sternocleidomastoid Release
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Post-Traumatic Headache
Abobotulinumtoxina Efficacy in Post-Traumatic Headache
This study will evaluate the efficacy of abobotulinumtoxina on Veterans with post-traumatic headache
- Trial name
- NCT03928496
- Testing
- AbobotulinumtoxinA, Normal saline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VA Greater Los Angeles Healthcare System
Tension-Type Headache, Cervicogenic Headache
The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.
This project comprises two studies; a cross-sectional study and a randomized controlled trial. 1. The goal of the cross-sectional study is to compare multiple outcome parameters in different headache types: tension type (TTH)…
- Conditions
- Tension-Type Headache, Cervicogenic Headache, Myofascial Headache
- Trial name
- COMPHAS_RCT (NCT06100588)
- Testing
- Dry Needling, Manual therapy
- Where
- Belgium
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University Ghent
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Headache, Cervical Pain
Comparison of Kinesiology Taping and Instrument Assisted Soft Tissue Mobilization in Cervicogenic Headache
To compare the effects of kinesiology taping and Instrument Assisted Soft Tissue Mobilization in cervicogenic headache
- Trial name
- NCT05474612
- Testing
- kinesiology taping with conventional therapy, Instrument assisted soft tissue mobilization with conventional therapy
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Post-Traumatic Headache, Concussion, Mild
Clinical Characteristics and Pathophysiology of Post-Traumatic Headache
To better understand the clinical characteristics and complex pathophysiological events that constitute persistent post-traumatic headache (PPTH) and to identify possible calcitonin gene-related peptide (CGRP) hypersensitivity in…
- Trial name
- NCT03791515
- Testing
- Calcitonin Gene-Related Peptide
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Cervicogenic Headache
The Effects of a Specific Exercise Program on Subjects With Cervicogenic Headache
This study explores with the use of MSK Ultrasound imaging if the obliquus capitis minor and the rectus capitis major can be contracted with specific exercises.
- Trial name
- NCT05500378
- Testing
- Head extension and rotation movement
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Post-Traumatic Headache, Head Trauma,Closed
Galantamine in the Treatment of Post-Traumatic Headache
Most patients with CPTH present with additional major cognitive, behavioral and somatic problems. Most drugs used currently have a negative influence on cognition.
- Conditions
- Post-Traumatic Headache, Head Trauma,Closed, Retention Disorders,Cognitive
- Trial name
- NCT00219869
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rapoport, Alan, M.D.