Clinical trials: Post Stroke Depression
Stroke
Post-stroke Psychosocial Recovery
Stroke is a neurological injury that adversely impacts psychosocial functioning and quality of life. This may occur due to direct insult to the brain circuits integral to adaptive psychosocial functioning, and/or indirectly via…
- Trial name
- NCT05380037
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Intracerebral Hemorrhage
ACT-group for Stroke Survivors (Pilot Study)
The goal of this clinical pilot trial is to test the feasibility, acceptance and preliminary efficacy of an adapted group psychotherapy manual in stroke survivors with psychological stress.
- Conditions
- Stroke, Intracerebral Hemorrhage, Depressive Symptoms, Anxiety
- Trial name
- NCT06282029
- Testing
- Group Therapy
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Bielefeld University
Post-stroke Depression
Acupuncture for Ischemic Post-stroke Depression
This is a multicentre, single Blind ,randomized controlled clinical trial in ischemic post-stroke depression patients.The participants will be allocated randomly in either of the two groups: verum acupuncture plus placebo…
- Trial name
- NCT02472613
- Testing
- acupuncture, Fluoxetine
- Where
- 3 sites in China
- Volunteers
- 208 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Stroke, Ischemic
The Efficacy of Citalopram Treatment in Acute Stroke
We wish to conduct a prospective, randomized, double blind, placebo controlled multi center study of the combined neuroprotective and antithrombotic effects of SSRI treatment after stroke.
- Trial name
- TALOS (NCT01937182)
- Testing
- Citalopram
- Where
- 3 sites in Denmark
- Volunteers
- 642 people
- Sponsor
- University of Aarhus
Post-stroke Depression
Efficacy and Safety of Jiedu Tongluo Granules for Post-stroke Depression
To explore the efficacy and safety of Jiedu Tongluo granules for post stroke depression. A randomized, double-blind, placebo-controlled clinical trial was designed.
- Trial name
- NCT03147053
- Testing
- Jiedu Tongluo granules
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Post-stroke Depression
Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke
Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive…
- Trial name
- NCT07294274
- Testing
- Group patients based on whether they have been diagnosed with PSD.
- Where
- China
- Volunteers
- 488 people
- Sponsor
- Min Su
Stroke, Post Stroke
An Ecological Momentary Assessment Based Program to Support Self-Management for Post-stroke Patients
The goal of this feasibility study is to test whether a new approach that combines real-time symptom tracking (Ecological Momentary Assessment) with machine learning can help people recovering from a stroke to better manage…
- Trial name
- NCT07691411
- Testing
- Ecological Momentary Assessment based Self-management Program
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Post-stroke Depression
Use of Transmucosal Ketamine in Post Stroke Depression
Studies have shown that ketamine is very effective and has a quick onset in treatment of depression. Most of these studies used intravenous ketamine in an inpatient setting and there are no large trials examining its use in Post…
- Trial name
- NCT04876066
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- West Virginia University
Post-stroke Depression
A Study of rTMS Personalized Precision Treatment of Post-stroke Depression
This is a multicenter, randomized trial aims to reveal the efficacy and safety of Repetitive transcranial magnetic stimulation (rTMS) individualized therapy based on the 'emotional loop destabilization' mechanism of PSD .One…
- Trial name
- NCT03256305
- Testing
- "personalized" rTMS+drug treatment, Traditional rTMS +drug treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhujiang Hospital
CVA (Cerebrovascular Accident), Ictus
Music Therapy in Post-Stroke Patients: A Clinical Trial
The goal of this clinical trial is to learn if music therapy works to optimizate sleep quality in patients who have suffered a stroke.
- Conditions
- CVA (Cerebrovascular Accident), Ictus, Stroke Acute, Insomnia
- Trial name
- NCT07899034
- Testing
- Music therapy
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Universidad de Granada
Cerebral Apoplexy, Depression Anxiety Disorder
Efficacy and Safety Evaluation of Remote Ischemic Adaptation ( Intermittent Pressure Stimulation ) in the Treatment of Insomnia After Stroke
The incidence of post-stroke depression is high, which will affect the rehabilitation of neurological function, damage cognitive function, and increase the risk of subsequent stroke recurrence.
- Conditions
- Cerebral Apoplexy, Depression Anxiety Disorder, Cerebrovascular Disease
- Trial name
- NCT07401784
- Testing
- Automatic ischemic preconditioning therapeutic apparatus
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Post-stroke Depression, Remote Ischemic Conditioning
Efficacy of Remote Ischemic Conditioning in Preventing Post-Stroke Depression
Post-stroke depression (PSD) is characterized primarily by low mood and loss of interest following a stroke. It is one of the most common and serious complications of stroke, with an incidence of 11% to 41% within two years…
- Trial name
- NCT06920706
- Testing
- RIC
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Xuanwu Hospital, Beijing
Depression, Stroke
Electroacupuncture Combined With Antidepressants for Post-stroke Depression
This is a randomized, assessor-blind, placebo controlled study in post stroke depression patients. Subjects receiving antidepressant drug would be assigned to either active or placebo scalp electro-acupuncture treatment, on the…
- Trial name
- NCT01174394
- Testing
- DCEAS (Hwato®/ Dongbang®), Body electro-acupuncture (Hwato®/ Dongbang®), n-CEA (Strietberger®)
- Where
- 3 sites in Hong Kong
- Volunteers
- 43 people
- Sponsor
- The University of Hong Kong
Stroke, Intervention
The Effectiveness and Mechanism of Character Strengths-based STEP Programme on Rehabilitation of Stroke Patients
There is an urgent need for educational and psychological adjustment to stimulate the post-stroke patients' motivation to actively carry out rehabilitation.
- Conditions
- Stroke, Intervention, Rehabilitation, Depression
- Trial name
- STEP (NCT05738499)
- Testing
- Character strengths-based structured treatment and education programme (CSSTEP), Structured treatment and education programme (STEP)
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Peking University
Stroke, Acute Stroke
Inflammation and Post-Stroke Depression
This study is being done to see if there is a relationship between stroke, post-stroke depression, and measures of inflammatory and/or stress compounds in the blood.
- Trial name
- NCT02368145
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Alexander Kusnecov, Ph.D.
Post-stroke Depression
The Antidepressant Effects of rTMS After Ischemic Stroke
This is a multicenter, randomized, double-blind, placebo-controlled trial aims to assess the effectiveness of repetitive transcranial magnetic stimulation(rTMS) in treating depression after basal ganglia ischemic stroke and to…
- Trial name
- NCT03159351
- Testing
- active rTMS treatment
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhujiang Hospital
Depression, Stroke
Ecosystem Focused Therapy in Post Stroke Depression
Older adults who are stroke survivors can experience many challenges, including depression, cognitive dysfunction, and physical disability.
- Trial name
- NCT01624402
- Testing
- Education on Stroke and Depression (ESD), Ecosystem Focused Therapy (EFT)
- Where
- 3 sites in United States
- Volunteers
- 151 people
- Sponsor
- Weill Medical College of Cornell University
Stroke Recurrence, Cardiovascular Events
Post-stroke Depression Treatment Effect on Stroke Recurrence
It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.
- Conditions
- Stroke Recurrence, Cardiovascular Events, Depression
- Trial name
- STROKE (NCT04776226)
- Testing
- Citalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 1,230 people
- Sponsor
- Ege University
Stroke, Stroke, Ischemic
Virtual Reality, Mood, and Sedentary Behaviour After Stroke
The purpose of this study is to: 1) evaluate the feasibility (e.g. recruitment and retention, administrative and participant burden) of a VR program to improve mood and sedentary behaviour in inpatient stroke survivors; and 2)…
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Lacunar
- Trial name
- NCT04011202
- Testing
- Virtual reality gaming program (VR-gaming program)
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of British Columbia