Clinical trials: Post Partum
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Breastfeeding, Postpartum Depression
Pacifiers and Breastfeeding Among Mothers at Risk for Postpartum Depression
We will enroll 40 mother-infant dyads in a randomized trial exploring the effect of distribution of pacifiers during the birth hospitalization to mothers at high risk for postpartum depression on pacifier use, infant feeding, and…
- Trial name
- NCT03709004
- Testing
- Pacifier
- Where
- United States
- Sponsor
- University of California, Davis
Postpartum Psychosis
Impact of Family Psychoeducation on Psychosis
There is currently no clear involvement of families/caregivers in the care for postpartum mothers that develop postpartum psychosis.
- Trial name
- NCT01172106
- Testing
- drug compliance, Encouragement of drug compliance, Family psychoeducation
- Where
- 2 sites in Uganda
- Volunteers
- 200 people
- Sponsor
- Makerere University
Substance Use Disorders, Simulation Training
Interprofessional Simulation Program for Clinical Resilience and Empathy: Project INSPIRE
The goal of this clinical trial is to develop and evaluate INSPIRE, an intervention for healthcare teams to improve care for individuals with substance use disorder (SUD) during their peri-delivery care.
- Conditions
- Substance Use Disorders, Simulation Training, Pregnancy Related, Patient-centered Care
- Trial name
- INSPIRE (NCT07707115)
- Testing
- INSPIRE
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Post Partum Hemorrhage
The Effect of Preoperative and Post Operative Misoprostol Administration on Intraoperative Blood Loss and Postpartum Hemorrhage in CS
Patients will be divided into two groups 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby The 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby plus…
- Trial name
- NCT03680339
- Testing
- cesarean section, Misoprostol, Oxytocin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Substance Use Disorders, Pregnancy Related
Implementation of a Patient-centered, Reproductive Planning Decision Support Tool (MyPath) Among Women With Substance Use Disorder in the Immediate Postpartum Period
This is a study to determine the effect of a novel patient-centered, reproductive planning decision support tool developed by the research team called MyPath on postpartum contraceptive decision-making among women with SUDs.
- Conditions
- Substance Use Disorders, Pregnancy Related, Contraception
- Trial name
- IMPACT (NCT04939012)
- Testing
- MyPath Intervention, Usual care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Pittsburgh
Postpartum
Effects of Manual Lymph Drainage on Breast Engorgement in Postpartum Period.
There have been many studies on the treatment of breast engorgement, there is a lack of research comparing the effectiveness of manual lymph drainage with massage.
- Trial name
- NCT06168630
- Testing
- Manual lymph drainage, Control group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Persons With Psychiatric Disorders
Perinatal Peer Support for Veterans With Serious Mental Illness
Veterans with serious mental illness (SMI) are at high risk of exacerbation of mental illness in pregnancy and postpartum, with consequences including poor pregnancy outcomes, decreased functioning, and impaired child…
- Trial name
- NCT07362576
- Testing
- Perinatal peer support
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Post-Partum Hemorrhage
Fibrinogen in Haemorrhage of Delivery
The purpose of the study is to assess the benefits of a therapeutic strategy that associates an early administration of human fibrinogen concentrate in the management of PPH on the reduction of bleeding after the initiation of…
- Trial name
- FIDEL (NCT02155725)
- Testing
- Human Fibrinogen concentrate
- Where
- 31 sites in France, Martinique
- Volunteers
- 448 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Overweight and Obesity, Vitamin A Deficiency
Individualized Dietary Intervention in Breastfeeding Women: Body Weight and Vitamin A Stores
Breast milk is the best food during the first 6mo of life because it offers multiple benefits for the mother-infant pair. An inadequate maternal diet during pregnancy can lead to excess weight gain, leading to negative health…
- Conditions
- Overweight and Obesity, Vitamin A Deficiency, Dietary Modification, Breastfeeding
- Trial name
- NCT03640104
- Testing
- Intervention-Nutrition guidelines, Nutrition guidelines
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Postnatal Depression
Behavioural Interventions for Postnatal Depression: a RCT Study
Randomized-controlled trial on the effectiveness of managing postnatal depression mothers at primary care clinics using Cognitive-behavioural therapy treatment by nurses as adjunct to management by Medical Officer as compared to…
- Trial name
- NCT03196726
- Testing
- Brief Cognitive Behavioral Therapy, standard management based on Clinical Practice Guideline
- Where
- 6 sites in Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
HIV Infections
Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum
The purpose of this study was to evaluate the pharmacokinetics, feasibility, acceptability, and safety of a fixed-dose combination of emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) as oral daily pre-exposure…
- Trial name
- NCT03386578
- Testing
- Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF), Behavioral HIV risk reduction package, Enhanced adherence support
- Where
- 7 sites in Malawi, South Africa and 2 more
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Postpartum
Postural Correction and Lumbar Stabilization vs MET for Postpartum Pain
This randomized clinical trial will evaluate the effectiveness of combined postural correction and lumbar stabilization exercises compared with Muscle Energy Technique (MET) in postpartum women with sacroiliac joint dysfunction…
- Trial name
- NCT07848425
- Testing
- Postural Correction and Lumbar Stabilization Exercises, Muscle Energy Technique (MET)
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Gestational Diabetes
Is Fat in the Liver a Marker of Post-Pregnancy Glycaemic Deterioration in Women With Gestational Diabetes?
The aim of this study is to utilise ultrasound, using an established method for detecting NAFLD, to determine whether the presence of NAFLD in women with GDM, detected during routine scanning, is a marker of deterioration in…
- Trial name
- FLiP-GD2 (NCT04362540)
- Testing
- MRI scan
- Where
- United Kingdom
- Volunteers
- 189 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Postpartum Hemorrhage
TRAnexamic Acid for Preventing Blood Loss Following a Cesarean Delivery in Women With Placenta pREVIA
Several randomized, controlled trials, mostly involving women undergoing cesarean delivery, have shown that the prophylactic intravenous administration of 1 g of tranexamic acid after childbirth reduced blood loss.
- Trial name
- TRAAPrevia (NCT04304625)
- Testing
- Tranexamic Acid / Sodium chloride
- Where
- France
- Volunteers
- 1,380 people
- Sponsor
- University Hospital, Bordeaux
Depression, Postpartum, Postpartum Depression
A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression
The purpose of this research study is to test the study drug, NORA520, as a possible treatment for severe postpartum depression (PPD).
- Conditions
- Depression, Postpartum, Postpartum Depression, Post-partum Depression, Postnatal Depression
- Trial name
- NuMom (NCT06285916)
- Testing
- NORA520 Dose 1, NORA520 Dose 2
- Where
- 18 sites in United States
- Volunteers
- 93 people
- Sponsor
- TWi Biotechnology, Inc.
HIV Infections, Tuberculosis
Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women
Tuberculosis (TB) is a leading cause of death among HIV-infected persons in low-income settings and can be a serious complication for HIV-infected pregnant women and their infants.
- Trial name
- NCT01494038
- Testing
- Isoniazid (INH)
- Where
- 13 sites in Botswana, Haiti and 6 more
- Volunteers
- 956 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Opioid Use Disorder, Pregnancy Related
Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD
The primary objective of this study is to evaluate the ability of TOME to increase Medication for Opioid Use Disorder (MOUD) and opioid-overdose knowledge in pregnant and postpartum persons.
- Conditions
- Opioid Use Disorder, Pregnancy Related, Substance Use, Drug Abuse
- Trial name
- TOME (NCT06262347)
- Testing
- Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME), Control
- Where
- 6 sites in United States
- Volunteers
- 131 people
- Sponsor
- T. John Winhusen, PhD
Fear of Birth, Birth Memory
Emotional Freedom Technique During Pregnancy
Emotional Freedom Technique (EFT), also known as "Tapping Therapy" and "Needleless Acupuncture", is a new and emerging complementary and energy-based therapy.
- Conditions
- Fear of Birth, Birth Memory, Postpartum Sense of Security
- Trial name
- NCT07000552
- Testing
- EFT intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Postpartum Hemorrhage, Simulation Based Medical Education
Effect of Simulation-Based Postpartum Hemorrhage Training on Team Performance in Senior Anesthesiology Teams
This prospective interventional study aims to evaluate the effect of simulation-based postpartum hemorrhage (PPH) training on team performance and crisis resource management skills among senior anesthesiology residents.
- Trial name
- PPH-SIM (NCT07519252)
- Testing
- Simulation-Based Postpartum Hemorrhage Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mehmet Kırıköz