Clinical trials: Post Operative Pulmonary Complications
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Pulmonary Complications;Abdominal Surgery
Postoperative Pulmonary Complications Between Patients Undergoing Abdominal Surgery in Plateau and Plain Areas
This study aims to collect perioperative diagnosis and treatment information of patients undergoing abdominal surgery at plateau and plain areas , collect blood and others samples for laboratory testing when necessary, analyzing…
- Trial name
- NCT05131009
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lung Cancer
Concomitant Tracheostomy and Lung Resection
This protocol has been designed to determine if tracheostomy performed immediately after lung operation (i.e. concomitant tracheotomy) could improve the postoperative outcome of high risk patients.
- Trial name
- NCT01053624
- Testing
- Tracheostomy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Locally Advanced Non-small Cell Lung Cancer (NSCLC)
Effect of Pre-operative Exercise Training on Cardiorespiratory Fitness in Patients With Locally Advanced Non-small Cell Lung Cancer Undergoing Induction Chemo-immunotherapy Followed by Surgery - a Randomized Controlled Study
The PREHAB study focuses on patients with locally advanced non-small cell lung cancer (NSCLC) undergoing neoadjuvant chemotherapy and/or immunotherapy prior to surgical resection.
- Trial name
- PREHAB (NCT07479407)
- Testing
- Preoperative Exercise Training
- Where
- 3 sites in Switzerland
- Volunteers
- 74 people
- Sponsor
- Hôpital du Valais
Preoperative Fasting, Perioperative Patient Comfort / Quality of Care
Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures
This single-center quality improvement project evaluates preoperative fasting times before elective procedures requiring anesthesiology care.
- Conditions
- Preoperative Fasting, Perioperative Patient Comfort / Quality of Care, Postoperative Nausea and Vomiting (PONV), Postoperative Pulmonary Complications
- Trial name
- NCT07488468
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University of Giessen
Ventilator-Induced Lung Injury, Mechanical Ventilation Complication
Protective Mechanical Ventilation and Risk of Postoperative Complications in Abdominal Surgery
Randomized controlled trial, comparing two groups of 40 patients each scheduled for open major abdominal surgery. The intervention group was ventilated with a protective strategy consisting on a low Tidal volume (Vt) (6ml/kg of…
- Conditions
- Ventilator-Induced Lung Injury, Mechanical Ventilation Complication, Postoperative Complications
- Trial name
- NCT03165760
- Testing
- protective ventilation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Ischemic Heart Disease, Post-Operative Complications
On-Pump vs. Off-Pump CABG in High-Risk Patients (EuroSCORE 6+)
Previous studies comparing on-pump and off-pump operating strategy did only partially demonstrate benefits of the off-pump myocardial revascularisation.In primary end-points (MI, death, renal failure, and so on) there was no…
- Trial name
- PRAGUE 6+ (NCT00606372)
- Testing
- OPCAB - the off-pump coronary artery bypass
- Where
- 2 sites in Czechia
- Volunteers
- 220 people
- Sponsor
- Charles University, Czech Republic
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Robotic Surgery, Mechanical Ventilation
Assessment of Ventilatory Management During General Anesthesia for Robotic Surgery
The aim of this study is to assess the incidence of postoperative pulmonary complications in patients undergoing mechanical ventilation during general anesthesia for robotic surgery, to characterize current practices of…
- Trial name
- AVATaR (NCT02989415)
- Testing
- Mechanical Ventilation
- Where
- 12 sites in United States, Belgium and 4 more
- Volunteers
- 1,015 people
- Sponsor
- Hospital Israelita Albert Einstein
Respiratory Failure, Acute Respiratory Failure Requiring Intubation
Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications
Respiratory complications represent the second most frequent type of postoperative complications with an incidence estimated to range from 2.0% to 7.9% It has been shown that intra-operative protective ventilation is associated…
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Intubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02399878
- Testing
- Inspiratory oxygen
- Volunteers
- 70,000 people
- Sponsor
- Massachusetts General Hospital
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Lung Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT02960971
- Testing
- Thoracic surgery for lung cancer
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Danish Pain Research Center
Postoperative Pulmonary Complications (PPCs), Postoperative Atelectasis
Optimal PEEP Level for Minimizing the Risk of Postoperative Atelectasis: A Retrospective Cohort Study Based on Lung Ultrasound Monitoring
Background: After surgery with general anesthesia, it is common for parts of the lungs to collapse, a condition called atelectasis. This can lead to low blood oxygen levels and other lung complications.
- Conditions
- Postoperative Pulmonary Complications (PPCs), Postoperative Atelectasis, Lung Ultrasound
- Trial name
- ULTRASVENT-1 (NCT07211074)
- Where
- Russia
- Volunteers
- 450 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Hypoxemia, Hypercapnia
Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements
Background Intermittent Positive Pressure Ventilation is used during general anesthesia but can lead to serious complications. Respiratory parameter settings can be adjusted to minimize the detrimental effects of this…
- Conditions
- Hypoxemia, Hypercapnia, Ventilator Associated Pneumonia, Complication of Anesthesia
- Trial name
- OPTIMVSPRIME (NCT06298435)
- Testing
- Intermittent Positive pressure ventilation
- Where
- Netherlands
- Volunteers
- 20,000 people
- Sponsor
- University Medical Center Groningen
Thoracic Diseases
Mechanical Insufflator-exsufflator in Patients After Video-assisted Thoracoscopic Operations With One-lung Ventilation
Postoperative pulmonary complications (PPC) are a common problem in patients undergoing surgery using one-lung invasive ventilation.
- Trial name
- NCT06180148
- Testing
- Mechanical insufflator-exsufflator
- Where
- Russia
- Volunteers
- 31 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Lung Neoplasms, Lung Cancer
Effect of Muscle and Skin Fixation of Thoracic Drainage Tube on Postoperative Pain
Lung cancer is the leading cause of cancer-related death worldwide. Thoracoscopic pulmonary resection is a prevalent management for early stage of lung cancer.
- Conditions
- Lung Neoplasms, Lung Cancer, Pulmonary Neoplasm, Postoperative Pain
- Trial name
- NCT05202249
- Testing
- muscle layer fixation of thoracic drainage tube
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Perioperative Mechanical Ventilation and Postoperative Monitoring of IPI
This study evaluates the influence of alveolar recruitment maneuver, protocolized liberation from respiratory support and monitoring of Integrated Pulmonary Index on the duration of the mechanical ventilation and the number of…
- Trial name
- WEAN-IPI (NCT02524522)
- Testing
- INTELLiVENT-ASV mode, SIMV mode
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Spinal Cord Injuries
Effect of Suctioning by Bronchoscope on Postoperative Pulmonary Complications Among Patients With SCI in the PACU
Respiratory failure and dyspnea are common in spinal cord injury (SCI), and in acute situations, any spinal cord lesion above T11 can cause abnormal respiratory function and impair the airway clearance.
- Trial name
- NCT04879602
- Testing
- suction with bronchoscopy
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Covid-19, SARS-CoV2
SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)
Overall mortality of COVID-19 is variable and has been reported to be between less than 1% and 7%. Many authors around the world also reported data on hospitalization rate, need for intensive care unit (ICU) care and need for…
- Conditions
- Covid-19, SARS-CoV2, Surgery, Surgical Procedure; Complications, Late Effect of Complications
- Trial name
- SUROCO (NCT04458337)
- Where
- Canada
- Volunteers
- 318 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
PONV
Comparison Between Opioid-Free Anaesthesia Versus Opioid Based Anesthesia in Reduction Postoperative Nausea and Vomiting (PONV)After Thoracoscopic Lung Resection.
The invistigators hypothesized that a protocolized OFA technique would lower the occurance of PONV in patients undergoing thoracoscopic lung surgery compared to standard opioid-based anaesthesia.
- Trial name
- NCT07806162
- Testing
- Opioid Free Anaesthesia, conventential opioid-based anaesthesia (OBA,
- Volunteers
- 120 people
- Sponsor
- Sohag University