Clinical trials: Post Operative Analgesia
Acute Pain
Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy
Living donor organ transplantation has increased in recent years due to an increased need for organs. The objective of this study was to investigate the effects of a TAP block on postoperative analgesia and opioid consumption in…
- Trial name
- NCT02645903
- Testing
- Transversus Abdominis Plane Block, standard general anesthesia
- Volunteers
- 50 people
- Sponsor
- Inonu University
Post Operative Analgesia
Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy
TAH, being a large scale gynaecological operation, is a construction bound to cause serious postoperative pain to the patient in that the procedure will inevitably entail massive tissue dissection.
- Trial name
- NCT07480499
- Testing
- Erector Spinae Plane Block, Quadratus Lumborum Block (QLB)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Chronic Pain
Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
The goal of this research proposal is to determine if the intraoperative administrative of Ketamine and Magnesium during laparoscopic gynecologic surgery improves postoperative pain in patients on chronic opioid therapy for…
- Trial name
- NCT02940509
- Testing
- Ketamine plus Magnesium sulfate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Lung Diseases, Lung Cancers
Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients
This prospective, observational study included ASA class II-III patients aged 18-70 years who underwent elective unilateral lobectomy via a thoracotomy.
- Trial name
- NCT06964698
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain, Postoperative, Satisfaction
Superficial Cervical Plexus Blockade for Clavicle Fracture Analgesia
The goal of the study is to determine if the addition of a superficial cervical plexus block to a traditional interscalene plexus block will provide superior perioperative analgesia to an interscalene brachial plexus blockade…
- Trial name
- NCT03187899
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post-operative Surgical Pain
Regional Anesthesia (Supra-Orbital and Infra-Orbital Nerve Block) (SION) for Pain Management in Trans-sphenoidal Hypophysectomy
This is a prospective, randomized, blinded, sham controlled regional anesthetic (supra-orbital and infra-orbital nerve block) pain study to compare the systemic postoperative pain medication requirements in patients having…
- Trial name
- SION (NCT04670614)
- Testing
- Nerve Block with ropivicaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain
Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Burn pain is known to be one the most severe forms of acute pain often requiring large amounts of narcotics in addition to other adjuvants.
- Trial name
- LidocaineBurn (NCT02229578)
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Total Hip Arthroplasty, Postoperative Pain
PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty
To compare the impact of pericapsular nerve group (PENG) block to intrathecal morphine on postoperative analgesia, motor function and side effects in patients undergoing primary total hip arthroplasty under spinal anesthesia.
- Trial name
- NCT05308420
- Testing
- Pericapsular nerve group (PENG) block, Spinal anesthesia, Intrathecal morphine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Kresimir Oremus, MD
Pain, Postoperative, Genetic Predisposition
COMT Activity and Hypnotizability
Hypnosis is an effective pain management tool for surgery that can reduce opioid use up to 40%. COMT single nucleotide polymorphisms (SNPs) can predict pain sensitivity and opioid use perioperatively, and may also be associated…
- Trial name
- NCT04624880
- Testing
- Giant magnetoresistive sensor (GMR)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Post Operative Pain, Acute
A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Serrartus Anterior Muscle Block in VATS as Regard Their Effectiveness in Post-operative Analgesia
A comparative study between ultrasound guided thoracic paravertebral block VS ultrasound guided serrartus anterior muscle block in video-assisted thoracoscopic surgeries as regard their effectiveness in post-operative analgesia
- Trial name
- NCT05971368
- Testing
- thoracic paravertebal block, serratus anterior muscle block
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis
Patient-controlled Intermittent epidural bolus versus epidural infusion for posterior spinal fusion after adolescent idiopathic scoliosis. Scoliosis surgery is commonly performed in adolescent due to idiopathic scoliosis.
- Trial name
- NCT02669004
- Testing
- Intermittent bolus epidural morphine, continuous epidural morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Inonu University
Uterine Diseases
Comparison Between Erector Spinae Plane Block and Transversus Abdominis Plane Block on Postoperative Analgesia After Total Abdominal Hysterectomy
This study aims to compare the ultrasound-guided bilateral erector spinae block versus the ultrasound-guided bilateral transversus abdominis plane block on postoperative analgesia after total abdominal hysterectomy.
- Trial name
- NCT05533710
- Testing
- erector spinae plane block, transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Postoperative Analgesia After Disc Surgery
Evaluation of Thoracolumbar Interfascial Plane Block for Postoperative Analgesia After Herniated Lumbar Disc Surgery
Several regional anesthesia have been shown to improve postoperative outcomes in many studies. The transversus abdominis plane (TAP) block provides anesthesia to the abdominal wall by introducing local anesthetic to the anterior…
- Trial name
- NCT03285282
- Testing
- Thoracolumber interfascial plane block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Postoperative Pain
Personalizing Perioperative Analgesia in Children
In the United States alone, each year approximately 5 million children undergo painful surgery, many of them experience serious side-effects with opioids and inadequate pain relief.
- Trial name
- NCT01140724
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Senthil Sadhasivam
Quadratus Lumborum Block, Surgical Wound Infiltration
Surgeon Infiltration QL Block Comparison
The purpose of this study is to learn if using a Quadratus Lumborum (QL) plane injection technique (also called a "nerve block") that numbs the nerves going to the abdominal area improve pain control after surgery compared to…
- Trial name
- NCT03496610
- Testing
- Liposomal Bupivicaine, QL Block
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Postoperative Pain Management, Analgesia, Postoperative
Superficial vs Deep Serratus Anterior Plane Block for Analgesia After Mammoplasty
The serratus anterior plane block (SAPB) is an ultrasound-guided fascial plane block used for perioperative analgesia in thoracic and breast surgeries.
- Conditions
- Postoperative Pain Management, Analgesia, Postoperative, Breast Surgery, Mammoplasty Patient
- Trial name
- DSAPvsSSAP (NCT07502846)
- Testing
- Superficial Serratus Anterior Plane Block, Deep Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain, Postoperative
Spinal Morphine for Postoperative Analgesia in Urology
The study was performed in urology patients elicited for open prostatectomy or open nephrectomy. Comparison of analgesic effect between group (M) with spinal morphine before general anaesthesia and group without this intervention…
- Trial name
- NCT03675646
- Testing
- Morphine
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Charles University, Czech Republic
Postoperative Pain
Sufentanil for Anesthesia Induction in Continuous Remifentanil Anesthesia
The appropriate management of postoperative pain is recognized as an important clinical challenge with implications beyond humanitarian issues.
- Trial name
- SAIRA (NCT01777100)
- Testing
- Sufentanil
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic