Clinical trials: Post Mastectomy Complications
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome
Paravertebral Versus Pectoralis Block for Post Mastectomy Pain
Post-mastectomy pain affects more than half of patients undergoing the procedure and can last for years. It has been well established that development of chronic pain is related to experienced pain in the perioperative period.
- Conditions
- Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome, Opioid Use
- Trial name
- NCT03656679
- Testing
- Pectoralis Blockade (PECs), Paravertebral Blockade
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Breast Cancer
Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery
There is little scientific data concerning the use of negative pressure therapy after immediate breast reconstruction. That strategy of treatment-reconstruction has expanded increasingly since the last years.
- Trial name
- TPN-SEIN (NCT06265558)
- Testing
- Negative pressure therapy (NPT), Dressing
- Where
- 7 sites in France
- Volunteers
- 254 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Breast Cancer Female
Cosmetic Outcome, Patient-reported Outcomes, and Reconstruction-related Complications in Breast Cancer Women Treated With or Without Post-mastectomy Radiation Therapy
This study aim to investigate the breast reconstruction outcome after mastectomy with or without radiation therapy from the patient's point of view.
- Trial name
- NCT03523078
- Testing
- Breast reconstructive surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Breast Cancer, Postoperative Pain
Comparison of Combined (Superficial and Deep) and Isolated Deep Serratus Anterior Plane Blocks After Breast Surgery
The main purpose of this study is to compare the effectiveness of two different regional anesthesia techniques for pain management after oncological breast surgeries.
- Conditions
- Breast Cancer, Postoperative Pain, Pain Management After Surgery
- Trial name
- NCT07724678
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- SBU Ankara Egitim ve Arastirma Hastanesi
Breast Cancer
Multidisciplinary Care Pathway With Electronic Patient Reported Outcomes (ePRO) Post-operative Follow-up of Breast Cancer Surgery Complications to Optimize Patient Quality of Life
This project is a follow-on study of the BEAUTIFY-2 study (NCT04957186). The "BEAUTIFY" (BrEast cAncer qUaliTy of lIfe aFter surgerY) program was built by a committee of experts on the basis of reflections carried out within 2…
- Trial name
- BEAUTIFY-3 (NCT05449340)
- Testing
- BEAUTIFY application
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Post Operative Pain
Comparing Between Ultrasound Guided Pectoral Nerve Block Versus Ultrasound Guided Mid-point Transverse Process Block for Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy
The aim of the study is to compare the effectiveness of ultrasound guided pectoral nerve block versus mid-point transverse process block for postoperative analgesia in patients undergoing modified radical mastectomy
- Trial name
- NCT06873893
- Testing
- Midpoint transverse process block, Pectoral Nerve Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Cancer, Pain
PECBLOCK for the Treatment of Pain After Breast Surgery
Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal…
- Trial name
- PECBLOC (NCT01670448)
- Testing
- PECBLOCK under echoguidance
- Where
- 2 sites in Canada, France
- Volunteers
- 128 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Magnesium Sulfate, Local Anesthetic
Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy
We aim to study the effect of adding magnesium sulfate as an adjuvant to the local anesthetic used in the combined Pectoralis Nerve Block II (PECS II) and stellate ganglion block for postoperative pain control in patients…
- Conditions
- Magnesium Sulfate, Local Anesthetic, Pectoral Nerve, Stellate Ganglion Block
- Trial name
- NCT06815887
- Testing
- Bupivacaine, Bupivacaine + Magnesium sulfate
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Skin Necrosis, Complication
Efficacy of Angiography With Indocyanine Green in the Identification of Complications After Breast Surgery
During the performance of oncoplastic surgery and skin-sparing or skin-nipple mastectomy there is a significant loss in the perfusion of the cutaneous envelope of the breast, which can produce areas of vascular suffering of the…
- Trial name
- NCT05910931
- Testing
- ICG angiography
- Where
- Spain
- Volunteers
- 221 people
- Sponsor
- University Hospital A Coruña
Post Mastectomy Lymphedema
Effect of Thera-Band Versus Swiss Ball Exercises on Postural Stability in Post Mastectomy Lymphedema
The purpose of the study is to determine the effect of Thera-band exercises versus Swiss ball exercises on postural stability in unilateral post mastectomy lymphedema.
- Trial name
- NCT07019311
- Testing
- Thera-Band exercises, Swiss ball exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD
Lymphedema of Upper Limb, Breast Cancer
Evaluation of the Treatment Response in Breast Cancer Related Lymphedema
This study aims to evaluate the effects of the treatment for breast cancer lymphedema. After taking a detailed history and giving a physical examination, breast cancer related lymphedema patients(n:30) will be informed and will…
- Conditions
- Lymphedema of Upper Limb, Breast Cancer, Breast Cancer Lymphedema
- Trial name
- NCT04766489
- Testing
- Complete Decongtestive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ege University
Post Operative Pain
Postoperative Anelgesic Effect of Rhomboid Intercostal Nerve Block Versus Erector Spinae Plane Block
Despite of analgesic effect of intravenous analgesic medications at intraoperative and postoperative time , The regional anesthetic techniquehas more benefits suchbetter control of Acute pain and hence less chronic pain and…
- Trial name
- NCT05452369
- Testing
- Rhomboid intercostal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- ghada fouad
Chronic Postsurgical Pain
Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain
The study utilizes a 3-arm placebo-controlled RCT to study the effectiveness of ketamine in reducing chronic post-mastectomy pain.
- Trial name
- KALPAS (NCT05037123)
- Testing
- Continuous ketamine infusion, Ketamine + Saline
- Where
- 14 sites in United States
- Volunteers
- 765 people
- Sponsor
- NYU Langone Health
Breast Cancer - Female
Effects of Negative Pressure Wound Bandaging After Mastectomy
Participant information sheet: Mastectomy is a surgical method used to treat breast cancer. A mastectomy involves the removal of the entire breast. A common postoperative complication after a mastectomy is seroma, i.e.
- Trial name
- NEPTAM (NCT07607366)
- Testing
- PICO negative pressure wound therapy by Smith and Nephew
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Dalarna County Council, Sweden
Post Operative Pain, Quality of Recovery After Mastectomy
Quality of Recovery From Mastectomy With and Without PECS Blocks
This is a prospective observational study. Investigators want to understand post-operative recovery for patients undergoing mastectomy at NorthShore University HealthSystem.
- Trial name
- NCT05795413
- Testing
- Mastectomy with PECS blocks, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Surgery Date, Age
Quality of Life of Patients Who Have Undergone Bilateral Mastectomy
The investigators therefore aim to determine whether the type of mastectomy (preventive in a high-risk patient or therapeutic in a patient with a history of cancer), as well as the timing (immediate or delayed) and type of breast…
- Conditions
- Surgery Date, Age, BMI, Height
- Trial name
- RM BREAST Q (NCT07699913)
- Volunteers
- 115 people
- Sponsor
- University Hospital, Grenoble
Pain, Postoperative
Serratus Anterior Plane (SAP) Block vs SAP Block Combined With Transverus Thoracic Plane (TTP) Block, for Post-mastectomy Pain Control.
a comparison shall be conducted between Serratus anterior plane block, on one hand, and transversus thoracic plane block combined with Serratus anterior plane block, on the other hand for management of post-mastectomy pain.
- Trial name
- NCT04375111
- Testing
- Serratus anterior plane block, Transversus thoracic plane block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Assiut University
Postoperative Pain
Erector Spinae Plane Block Versus Paravertebral Block in Mastectomy
In this randomized, controlled, observer-blinded study the investigators plan to evaluate ultrasound-guided thoracic paravertebral block (TPVB) and ultrasound-guided thoracic erector spinae plane (TESP) block for postoperative…
- Trial name
- NCT03490006
- Testing
- Erector Spinae Plane Block, Paravertebral Block
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Post Mastectomy Lymphedema
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.
- Trial name
- NCT07576270
- Testing
- Resisted Deep Breathing, Myofascial release
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University