Clinical trials: Post Discharge
Depressive Disorder
Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects
The primary purpose of this study is to compare the steady-state pharmacokinetic profile of paroxetine CR (controlled-release) at the dosage of 25mg/day using the proposed final market tablet of CR 25mg in Japan with that of…
- Trial name
- NCT01000857
- Testing
- Paroxetine CR and Paroxetine IR
- Where
- Japan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Muscle Soreness
The Effects of Swedish Massage and Manual Lymph Drainage on Muscle Fatigue
12 healthy men aged 18-30 will be included in the study. Participants will be selected from students who regularly train and do active sports at the Faculty of Sports Sciences. All participants will do nordic hamstring exercise.
- Trial name
- NCT06112899
- Testing
- Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Satiety Hormones, Short-chain Fatty Acids
The Impact of Short-Chain Fatty Acids on Gut Hormone Release After Delivery in the Small and Large Intestine of Healthy Volunteers
The goal of this crossover study is to evaluate the impact of short-chain fatty acids (SCFA) on the gut hormone release after administration in the small intestine or colon in healthy participants.
- Conditions
- Satiety Hormones, Short-chain Fatty Acids, Satiety and Appetite, Intestinal Absorption
- Trial name
- Histine (NCT06686888)
- Testing
- SCFA, microcristalline cellulose
- Where
- Belgium
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy
PK Study of Pregabalin GLARS Tablet 150mg and IR Formulation After Multiple Dosing Under Fed Condition in Healthy Male Subjects
The purpose of this clinical trial is to compare the pharmacokinetic characteristics of GLA5PR GLARS tablet 150mg and Lyrica Capsule 75mg. GLA5PR GLARS tablet 150mg is a New Formulation which is made by GL Pharm Tech.
- Trial name
- GLA5PR-102 (NCT01638273)
- Testing
- Pregabalin 150mg, Pregabalin 75mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Opioid Use
Discharge Opioid Education to Decrease Opioid Use After Cesarean
Background: The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic.
- Trial name
- NCT03678870
- Testing
- Opioid Education Handout
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Lung Diseases
The Feasibility and Safety of Avoiding Chest Tube Placement After Video-assisted Thoracoscopic Surgery (VATS）of the Lung
This is a prospective randomized controlled trial.The main study content is the feasibility and safety of avoiding chest tube placement after Video-Assisted Thoracoscopic Surgery lung disease,participants were randomly divided…
- Trial name
- NCT04012554
- Testing
- avoid chest drainage tube placement after video-assisted thoracoscopic wedge resection of lung, Indewlling chest drainage tube after video-assisted thoracoscopic wedge resection of lung
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xueying Yang
Tuberculosis; Uveitis (Manifestation), Anti-Tuberculous Drug Reaction
Proportion of Clinical Improvement & Type 1 Interferon (IFN) Score Changes in Idiopathic Uveitis Patients With Interferon Gamma Release Assay (IGRA) Positive
The aim of this study is to determine the proportion of clinical improvement, the score changing of type 1 interferon selected gene expression, and analysis of transcriptomics profiling in patients with idiopathic uveitis…
- Conditions
- Tuberculosis; Uveitis (Manifestation), Anti-Tuberculous Drug Reaction, Tuberculous Uveitis
- Trial name
- NCT04088019
- Testing
- Fixed drug combination (FDC) of ATT and Oral steroid
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Allergic Rhinitis
The Effects of OC000459 on Nasal Mediators
This is the first proof of concept study for OC000459 and is undertaken to assess the effects of the compound on the development of inflammatory cytokines in a model (nasal allergen challenge model) that is validated and…
- Trial name
- NCT00290381
- Testing
- Oxagen OC000459
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Trevor Hansel
COVID-19 Respiratory Infection
Cardiovascular Disease and Outcomes Among Patients With SARS-CoV-2 Infection (COVID-19)
The coronavirus disease of 2019 (COVID-19) has affected over 2.4 million individuals worldwide and has resulted in >171,000 deaths. Cardiovascular disease (CVD) is an important contributor to death in these patients.
- Trial name
- NCT05085262
- Testing
- Bloodwork, Echocardiogram, PET/MRI, Bloodwork, Echocardiogram, MRI
- Where
- Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Mental Illness
Recovery Bridge: Peer Intervention to Bridge Transition Post Discharge
The time following discharge from psychiatric hospitalization is a high-risk period and has been associated with a range of negative outcomes including high rates of hospital readmission and suicide.
- Trial name
- NCT05758376
- Testing
- Recovery Bridge
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Critical Illness, Delirium in the Intensive Care Unit
Pilot Feasibility Study of a Pragmatic Mixed-Methods Randomized Controlled Trial on a Follow-Up Bundle of Care for ICU Survivors and Caregivers
~80% of ICU survivors experience profound long-term cognitive, physical, and psychiatric impairments known as post-intensive care syndrome (PICS).
- Trial name
- IMPACT-ICU (NCT06681649)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Healthy Volunteers
Effect of Antacid on Bioavailability of Febuxostat After Administration of a Febuxostat 80 mg Extended-Release Capsule
The purpose of this study is to assess the effect of antacid administration, and its timing, on the bioavailability of a single dose of febuxostat extended-release (XR) 80 mg.
- Trial name
- NCT02382640
- Testing
- Febuxostat XR, Maalox Advance Regular Strength liquid
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Takeda
Adverse Outcomes Post-hospital Discharge
Improving Posthospital Medication Management of Older Adults Through Health IT
The incidence of drug-induced injury is high in the ambulatory geriatric population and is increased for elders upon transition from the hospital to the ambulatory setting.
- Trial name
- NCT00611091
- Testing
- Electronic delivery of enhanced discharge information to the ambulatory physician
- Where
- United States
- Volunteers
- 5,077 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
HIV-I
Innovation-TiFP4-C101: A Study to Evaluate the Pharmacokinetics of TMC114 and TMC41629 After a Single Oral Dose of 2 Controlled-release Coformulations as Compared to an Immediate-release Coformulation of TMC114/TMC41629
The purpose of this study is to compare the bioavailability (the degree to which a drug becomes available in the body after administration) of 3 different pharmaceutical preparations of a combination of two drugs, TMC114 and…
- Trial name
- NCT00854204
- Testing
- TMC114; TMC41629
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Healthy
Clinical Trial to Compare The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg and Immediate Release Formulation
The purpose of this study is to compare the pharmacokinetics profiles of pregabalin sustained release tablet (300mg) to immediate release capsule(150mg * 2) while multiple dosing.
- Trial name
- NCT02103647
- Testing
- Immediate release capsule(lyrica 150mg * 2/day), sustained release tablet
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Postoperative Period
Fast-track Discharge After Elective Cesarean Section
Cesarean section (CS) is a procedure with prolonged hospital stay compared to the routine for normal vaginal delivery in multiparas.
- Trial name
- NCT02911727
- Testing
- Fast-track discharge
- Where
- Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Infant Development
Evaluation of Preterm Infants Fed Post-Discharge Preterm Infant Formula
This single-group study will assess growth and tolerance of infants fed a post-discharge preterm infant formula containing a prebiotic.
- Trial name
- NCT03991949
- Testing
- Experimental Infant Formula
- Where
- 7 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Pharmacokinetics
Open-Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Tamoxifen When Coadministered To Healthy Post-Menopausal Female Subjects
The goal of this study is to evaluate the effect of multiple doses of Desvenlafaxine SR on the pharmacokinetics of Tamoxifen and endoxifen when coadministered to healthy post-menopausal female subjects.
- Trial name
- NCT01189500
- Testing
- Tamoxifen, Tamoxifen and Desvenlafaxine Succinate Sustained Release
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer
Fibromyalgia
Effectiveness of Myofascial Release Versus Manual Lymphatic Drainage After Breast Cancer Surgery
Objective. To compare the effectiveness of myofascial therapy against manual lymphatic drainage in the reduction of sequelae secondary to conservative surgery and radiotherapy in women who survived breast cancer. Design.
- Trial name
- MRvsMLD (NCT03182881)
- Testing
- Lymphatic Drainage, Myofascial Release
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia